Ewch i’r prif gynnwys

Infection and immunity

Mae'r cynnwys hwn ar gael yn Saesneg yn unig.

We conduct high quality basic and translational research that is internationally recognised, widely referenced and globally exploited for the benefit of human health.

Our research is grouped into four themes, each led by an integrated team of non-clinical and clinical academic staff who deliver fundamental and applied research of translational relevance. Many of our clinical research leads have joint NHS appointments combined with protected research time.

We deliver a large component of teaching within undergraduate medical and pharmacology teaching programmes in the form of lectures, practicals, tutorials and demonstrations, with an emphasis on small group teaching within years 2 - 4. We are also involved in postgraduate teaching, teaching administration, assessment and curriculum development.

The majority of our research is conducted through the Systems Immunity Research Institute.

Aims

  • To understand the underlying biology of infectious diseases.
  • To understand immune system function and dysfunction during health and disease.
  • To exploit this understanding to develop novel therapeutic and diagnostic approaches.
  • To disseminate this knowledge to the public, patients, professionals and students.

Themes

Mae'r cynnwys hwn ar gael yn Saesneg yn unig.

Infection

We have a broad portfolio of research interests with particular strengths in virology, viral immunology, antimicrobial resistance and diagnosis of fungal infection.

Close links with the NHS and industrial partners facilitate translational research and allow clinical evaluation of novel methodologies and diagnostics.

Theme lead

Professor Ian Humphreys

Yr Athro Ian Humphreys

Wellcome Trust Senior Research Fellow

Email:
humphreysir@caerdydd.ac.uk

Area of interest

Cytokine immunology.

Principal members of staff

NameArea of interest
Professor Tim WalshAntibiotic resistance in bacteria
Professor Gavin Wilkinson 
Dr Brad (Owen) Spiller  
Dr Mark Toleman Antibiotic resistance in bacteria
Professor Sailesh Kotecha Clinical paediatrics and infection in babies
Dr Edward Wang Cellular immunology
Dr Richard Stanton Virology
Dr Kristin Ladell Mechanisms of adaptive immunity
Professor David Price Mechanisms of adaptive immunity

Research Groups

Mae'r cynnwys hwn ar gael yn Saesneg yn unig.

Inflammation

Inflammation represents the coordinated immune response to infection, trauma and injury.

When appropriately controlled, inflammation ensures competent host defence and prevents excessive damage of the affected tissue or organ structure.

In chronic inflammatory diseases, this process is disrupted and instead of offering protection, drives disease progression.

Theme lead

Dr Ann Ager

Yr Athro Ann Ager

Reader

Email:
agera@caerdydd.ac.uk
Telephone:
+44 (0)29 2068 8872

Area of interest

Cytokine immunology in chronic disease progression.

Principal members of staff

NameArea of interest
Professor Ernest ChoyClinical rheumatology and biologic drug therapies
Dr Charlotte Rawlings Clinical rheumatology
Professor Andrew Finlay Infection
Professor Paul MartinCancer and wound healing
Dr John Ingram Clinical dermatology
Professor Valerie O'DonnellLipidomics
Professor Peter Collins Clinical haematology and clotting
Professor Paul Morgan Complement biology, neuroimmunology
Professor Kathy Triantafilou 
Dr Martha Triantafilou Innate sensing mechanisms
Dr Timothy Hughes Complement biology, cardiovascular disease
Professor Donald Fraser Clinical nephrology and fibrosis
Dr Timothy Bowen MicroRNA
Dr Mario Labeta Innate sensing mechanisms
Dr Anne-Catherine RabyInnate sensing mechanisms
Professor Aled Phillips Clinical nephrology and renal scarring
Dr Robert Steadman Clinical nephrology and renal scarring
Dr Soma MeranClinical nephrology and fibrosis
Professor Philip Taylor Monocytic cell biology
Professor Anwen WilliamsExperimental rheumatology
Dr Gareth JonesCytokine immunology in chronic disease progression
Dr Selinda Orr Innate sensing mechanisms

Research Groups

Mae'r cynnwys hwn ar gael yn Saesneg yn unig.

Immunology

Our immunology research spans the gamut from basic molecular studies through to clinical trials and new patient treatments.

We are particularly strong in the areas of conventional and unconventional T-cell immunity, cancer immunotherapy, autoimmune disease, homing and trafficking of immune cells and the structure biology of antigen receptors and the ligands they recognise.

Theme lead

Andrew Sewell

Yr Athro Andrew Sewell

Professor

Email:
sewellak@caerdydd.ac.uk
Telephone:
+44 (0)29 2068 7055

Area of interest

T-cell ligands and the receptors that recognise them during infection, autoimmune disease, organ transplant and cancer immunotherapy.

Principal members of staff

NameArea of interest
Professor Jamie RossjohnStructure and biophysics of innate and adaptive immune recognition
Dr Pierre Rizkallah Protein structure biology
Professor Colin DayanAutoimmune disease
Professor Susan Wong Type 1 diabetes
Professor Marian Ludgate Graves’ disease
Professor Bernhard Moser Immune cell migration
Professor Andrew Godkin MHC class II and cancer immunotherapy
Professor Awen Gallimore Immune tolerance and cancer immunotherapy
Professor Matthias Eberl Unconventional T-cells
Professor Ann Ager Lymphocyte homing

Research Groups