Yr Athro Sailesh Kotecha

2020

• Lowe, J.et al. 2020. Study protocol: azithromycin therapy for chronic lung disease of prematurity (AZTEC) - a randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants. BMJ Open 10(10), article number: e041528. (10.1136/bmjopen-2020-041528)
• Kotecha, S. . J.et al. 2020. Differential association of air pollution exposure with neonatal and postneonatal mortality in England and Wales: A cohort study. PLoS Medicine 17(10), article number: e1003400. (10.1371/journal.pmed.1003400)
• Gallacher, D.et al. 2020. Dissimilarity of the gut-lung axis and dysbiosis of the lower airways in ventilated preterm infants. European Respiratory Journal 55(5), article number: 1901909. (10.1183/13993003.01909-2019)

2019

• Poon, C. Y.et al. 2019. Longitudinal evaluation of myocardial function in preterm infants with respiratory distress syndrome. Echocardiography 36(9), pp. 1713-1726. (10.1111/echo.14462)
• Course, C. W., Kotecha, S. and Kotecha, S. J. 2019. Fractional exhaled nitric oxide in preterm-born subjects: A systematic review and meta-analysis. Pediatric Pulmonology 54(5), pp. 595-601. (10.1002/ppul.24270)

2018

• Kotecha, S., Lowe, J. and Kotecha, S. 2018. Effect of foetal and infant growth and body composition on respiratory outcomes in preterm-born children. Paediatric Respiratory Reviews 28, pp. 55-62. (10.1016/j.prrv.2017.12.001)
• Urs, R.et al. 2018. Persistent and progressive long-term lung disease in survivors of preterm birth. Paediatric Respiratory Reviews 28, pp. 87-94. (10.1016/j.prrv.2018.04.001)
• Lowe, J.et al. 2018. Effect of fetal and infant growth on respiratory symptoms in preterm-born children. Pediatric Pulmonology 53(2), pp. 189-196. (10.1002/ppul.23920)
• Cousins, M.et al. 2018. Long-term respiratory outcomes following preterm birth. Revista Médica Clínica Las Condes 29(1), pp. 87-97. (10.1016/j.rmclc.2018.02.002)

2017

• Kotecha, S. J., Chakraborty, M. and Kotecha, S. 2017. Nasal continuous positive airway pressure outperforms heated high-flow nasal cannula therapy as primary respiratory therapy in preterm infants. Evidence-Based Medicine 22(2), pp. 63. (10.1136/ebmed-2016-110618)
• Lowe, J.et al. 2017. Physical activity outcomes following preterm birth. Paediatric Respiratory Reviews 22, pp. 76-82. (10.1016/j.prrv.2016.08.012)

2016

• Kotecha, S.et al. 2016. Effect of early-term birth on respiratory symptoms and lung function in childhood and adolescence. Pediatric Pulmonology 51(11), pp. 1212-1221. (10.1002/ppul.23448)
• Stuchfield, P., Kotecha, S. and Doull, I. 2016. Antenatal Betamethasone for women at risk for late preterm delivery. New England Journal of Medicine 375(5), pp. 485-487. (10.1056/NEJMc1605902)
• Poon, C. Y.et al. 2016. Pulmonary arterial response to hypoxia in survivors of chronic lung disease of prematurity. Archives of Disease in Childhood-Fetal and Neonatal Edition 101(4), pp. F309-F313. (10.1136/archdischild-2015-309015)
• Kotecha, S. J., Gallacher, D. J. and Kotecha, S. 2016. The respiratory consequences of early-term birth and delivery by caesarean sections. Paediatric Respiratory Reviews 19, pp. 49-55. (10.1016/j.prrv.2015.12.002)
• Edwards, M.et al. 2016. Management of prematurity-associated wheeze and its association with atopy. PLoS ONE 11(5), article number: e0155695. (10.1371/journal.pone.0155695)
• Lowe, J.et al. 2016. Physical activity and sedentary behavior in preterm-born 7-year old children. PLoS ONE 11(5), article number: e0155229. (10.1371/journal.pone.0155229)
• Watkins, W. J., Kotecha, S. J. and Kotecha, S. 2016. All-cause mortality of low birthweight infants in infancy, childhood, and adolescence: population study of England and Wales. PLOS MEDICINE 13(5), article number: e1002018. (10.1371/journal.pmed.1002018)
• Gallacher, D., Hart, K. and Kotecha, S. 2016. Common respiratory conditions of the newborn. Breathe 12(1), pp. 30-42. (10.1183/20734735.000716)
• Gallacher, D. J. and Kotecha, S. 2016. Respiratory microbiome of new-born infants. Frontiers in Pediatrics 4(10), pp. 794-802., article number: 10. (10.3389/fped.2016.00010)

2015

• Smith, C.et al. 2015. Use and safety of azithromycin in neonates: a systematic review. BMJ Open 5(12), article number: e008194. (10.1136/bmjopen-2015-008194)
• Bolton, C. E.et al. 2015. Republished: Lung consequences in adults born prematurely. Postgraduate Medical Journal 91(1082), pp. 712-718. (10.1136/postgradmedj-2014-206590rep)
• Kotecha, S. J.et al. 2015. Safety and efficacy of high-flow nasal cannula therapy in preterm infants: a meta-analysis. Pediatrics 136(3), pp. 542-555. (10.1542/peds.2015-0738)
• Edwards, M. O.et al. 2015. Early-term birth is a risk factor for wheezing in childhood: A cross-sectional population study. Journal of Allergy and Clinical Immunology 136, pp. 581-587.e2. (10.1016/j.jaci.2015.05.005)
• Bolton, C. E.et al. 2015. Lung consequences in adults born prematurely. Thorax 70, pp. 574-580. (10.1136/thoraxjnl-2014-206590)
• Kotecha, S. J.et al. 2015. The effect of birth weight on lung spirometry in white, school-aged children and adolescents born at term: a longitudinal population based observational cohort study. The Journal of Pediatrics 166(5), pp. 1163-1167. (10.1016/j.jpeds.2015.01.002)
• Lowe, J.et al. 2015. Physical activity in school-age children born preterm. The Journal of Pediatrics 166(4), pp. 877-883. (10.1016/j.jpeds.2014.12.013)
• Pansieri, C.et al. 2015. European survey evaluating the use of azithromycin in neonates. Fundamental and Clinical Pharmacology 29(S1), pp. 43-43., article number: PM2-039. (10.1111/fcp.12106)
• Kotecha, S.et al. 2015. Effect of bronchodilators on forced expiratory volume in 1 s in preterm-born participants aged 5 and over: a sytematic review. Neonatology 107(3), pp. 231-240. (10.1159/000371539)
• Edwards, M.et al. 2015. Effect of preterm birth on exercise capacity: a systematic review and meta-analysis. Pediatric Pulmonology 50(3), pp. 293-301. (10.1002/ppul.23117)

2014

• Chakraborty, M.et al. 2014. Role of serine proteases in the regulation of interleukin-877 during the development of bronchopulmonary dysplasia in preterm ventilated infants. PLoS ONE 9(12), article number: e114524. (10.1371/journal.pone.0114524)
• Legrand, T.et al. 2014. An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples. Bioanalysis 6(17), pp. 2317-2328. (10.4155/bio.14.81)
• Paranjothy, S.et al. 2014. Perinatal outcomes and travel time from home to hospital: Welsh data 1995 to 2009. Acta Paediatrica 103(12), pp. e522-e527. (10.1111/apa.12800)
• Joshi, S.et al. 2014. Cardiovascular function in children who had chronic lung disease of prematurity. Archives of Disease in Childhood. Fetal and neonatal edition 99(5), pp. F373-F379. (10.1136/archdischild-2013-305185)
• Edwards, M.et al. 2014. Higher systolic blood pressure with normal vascular function measurements in preterm-born children. Acta Paediatrica 103(9), pp. 904-912. (10.1111/apa.12699)
• Prince, L. R.et al. 2014. Macrophage phenotype is associated with disease severity in preterm infants with chronic lung dsease. PLoS ONE 9(8), article number: e103059. (10.1371/journal.pone.0103059)
• Lowe, J.et al. 2014. Association between pulmonary Ureaplasma colonization and bronchopulmonary dysplasia in preterm infants: updated systematic review and meta-analysis. The Pediatric Infectious Disease Journal 33(7), pp. 697-702. (10.1097/INF.0000000000000239)
• Cherian, S.et al. 2014. Oxygen therapy in preterm infants. Paediatric Respiratory Reviews 15(2), pp. 135-141. (10.1016/j.prrv.2012.12.003)
• Kotecha, S. 2014. Mini-symposium: oxygen and infancy. Paediatric Respiratory Reviews 15(2), pp. 119. (10.1016/j.prrv.2014.04.012)
• Pickerd, N.et al. 2014. Tidal breathing in preterm infants receiving and weaning from continuous positive airway pressure. The Journal of Pediatrics 164(5), pp. 1058-1063.e1. (10.1016/j.jpeds.2013.12.049)
• Pansieri, C.et al. 2014. Ureaplasma, bronchopulmonary dysplasia, and azithromycin in European neonatal intensive care units: a survey. Scientific Reports 4, article number: 4076. (10.1038/srep04076)

2013

• Poon, C., Edwards, M. and Kotecha, S. 2013. Long term cardiovascular consequences of chronic lung disease of prematurity. Paediatric Respiratory Reviews 14(4), pp. 242-249. (10.1016/j.prrv.2012.08.003)
• Poon, C. Y.et al. 2013. Assessment of pulmonary artery pulse wave velocity in children: An MRI pilot study. Magnetic Resonance Imaging 31(10), pp. 1690-1694. (10.1016/j.mri.2013.08.006)
• Kotecha, S.et al. 2013. Functional heterogeneity of pulmonary surfactant protein-D in cystic fibrosis. Biochimica et Biophysica Acta - Molecular Basis of Disease 1832(12), pp. 2391-2400. (10.1016/j.bbadis.2013.10.002)
• Kotecha, S. 2013. Should asymptomatic congenital cystic adenomatous malformations be removed? The case against. Paediatric Respiratory Reviews 14(3), pp. 171-172. (10.1016/j.prrv.2013.06.002)
• Kotecha, S. J.et al. 2013. Effect of preterm birth on later FEV1: a systematic review and meta-analysis. Thorax 68(8), pp. 760-766. (10.1136/thoraxjnl-2012-203079)
• Triantafilou, M.et al. 2013. Synergic activation of Toll-Like Receptor (TLR) 2/6 and 9 in response to ureaplasma parvum & urealyticum in human amniotic epithelial cells. PLoS ONE 8(4), article number: e61199. (10.1371/journal.pone.0061199)
• Edwards, M., Kotecha, S. J. and Kotecha, S. 2013. Respiratory distress of the term newborn infant. Paediatric Respiratory Reviews 14(1), pp. 29-37. (10.1016/j.prrv.2012.02.002)
• Pickerd, N., Williams, E. M. and Kotecha, S. 2013. Electromagnetic inductance plethysmography to measure tidal breathing in preterm and term infants. Pediatric Pulmonology 48(2), pp. 160-167. (10.1002/ppul.22584)
• Kotecha, S.et al. 2013. Increased prevalence of low oligomeric state surfactant protein D with restricted lectin activity in bronchoalveolar lavage fluid from preterm infants. Thorax 68(5), pp. 460-467. (10.1136/thoraxjnl-2012-202729)
• Francis, R. J., Kotecha, S. and Hallett, M. B. 2013. Ca2+ activation of cytosolic calpain induces the transition from apoptosis to necrosis in neutrophils with externalized phosphatidylserine. Journal of Leukocyte Biology 93(1), pp. 95-100. (10.1189/jlb.0412212)
• Triantafilou, K.et al. 2013. Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation. Thorax 68(1), pp. 66-75. (10.1136/thoraxjnl-2012-202182)
• Parris, T.et al. 2013. Inversion upstream of FOXF1 in a case of lethal alveolar capillary dysplasia with misalignment of pulmonary veins. American Journal of Medical Genetics Part A 161(4), pp. 764-770. (10.1002/ajmg.a.35832)
• Chakraborty, M.et al. 2013. Role of interleukin-6, its receptor and soluble gp130 in chronic lung disease of prematurity. Neonatology 104(3), pp. 161-167. (10.1159/000351015)

2012

• Bolton, C. E.et al. 2012. Are early life factors considered when managing respiratory disease? A British Thoracic Society survey of current practice [Letter]. Thorax 67(12), pp. 1110. (10.1136/thoraxjnl-2012-202637)
• Joshi, S.et al. 2012. Exercise-induced bronchoconstriction in school-aged children who had chronic lung disease in infancy. The Journal of Pediatrics 162(4), pp. 813-818. (10.1016/j.jpeds.2012.09.040)
• Kotecha, S.et al. 2012. Antenatal and postnatal management of congenital cystic adenomatoid malformation. Paediatric Respiratory Reviews 13(3), pp. 162-171. (10.1016/j.prrv.2012.01.002)
• Kotecha, S. and Kotecha, S. J. 2012. Long term respiratory outcomes of perinatal lung disease [Editorial]. Seminars in Fetal and Neonatal Medicine 17(2), pp. 65-66. (10.1016/j.siny.2012.01.001)
• Beeton, M. L.et al. 2012. Serum killing of 'ureaplasma parvum' shows serovar-determined susceptibility for normal individuals and common variable immuno-deficiency patients. Immunobiology 217(2), pp. 187-194. (10.1016/j.imbio.2011.07.009)
• Kotecha, S.et al. 2012. Congenital diaphragmatic hernia. European Respiratory Journal 39(4), pp. 820-829. (10.1183/09031936.00066511)
• Kotecha, S. J., Dunstan, F. D. and Kotecha, S. 2012. Long term respiratory outcomes of late preterm-born infants. Seminars in Fetal and Neonatal Medicine 17(2), pp. 77-81. (10.1016/j.siny.2012.01.004)

2011

• Beeton, M. L.et al. 2011. Role of pulmonary infection in the development of chronic lung disease of prematurity. European Respiratory Journal 37(6), pp. 1424-1430. (10.1183/09031936.00037810)
• Francis, R. J., Kotecha, S. and Hallett, M. B. 2011. Ca2+ events in apoptosis and necrosis of neutrophils [Abstract]. European Journal of Clinical Investigation 41(s1), pp. 46-47. (10.1111/j.1365-2362.2011.02508.x)
• Williams, E. M.et al. 2011. Estimation of tidal ventilation in preterm and term newborn infants using electromagnetic inductance plethysmography. Physiological Measurement 32(11), pp. 1833-1845. (10.1088/0967-3334/32/11/001)
• Poon, C.et al. 2011. Optimization of myocardial deformation imaging in term and preterm infants. European Journal of Echocardiography 12(3), pp. 247-254. (10.1093/ejechocard/jeq192)
• Turner, M. A., Jacqz-Aigrain, E. and Kotecha, S. 2011. Azithromycin, ureaplasma and chronic lung disease of prematurity: a case study for neonatal drug development. Archives of Disease in Childhood 97(6), pp. 573-577. (10.1136/adc.2010.195180)
• Clark, S. R.et al. 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117(6), pp. 2033-2043. (10.1182/blood-2010-04-278887)
• Kotecha, S. J.et al. 2011. Effect of late preterm birth on longitudinal lung spirometry in school age children and adolescents. Thorax 67(1), pp. 54-61. (10.1136/thoraxjnl-2011-200329)
• McGreal, E. P.et al. 2011. Dynamic expression of IL-6 trans-signalling molecules in the lungs of preterm baboons undergoing mechanical ventilation. Neonatology 100(2), pp. 130-138. (10.1159/000322148)

2010

• Chakraborty, M., McGreal, E. P. and Kotecha, S. 2010. Acute lung injury in preterm newborn infants: mechanisms and management. Paediatric Respiratory Reviews 11(3), pp. 162-170. (10.1016/j.prrv.2010.03.002)
• Kotecha, S.et al. 2010. An analysis of the effect of intrauterine growth retardation on spirometric lung function measures of 8-year-old children [Abstract]. Journal of Epidemiology & Community Health 64(Supp 1), pp. A24. (10.1136/jech.2010.120956.60)
• Kotecha, S. J.et al. 2010. Spirometric lung function in school-age children: Effect of intrauterine growth retardation and catch-up growth. American Journal of Respiratory and Critical Care Medicine 181(9), pp. 969-974. (10.1164/rccm.200906-0897OC)
• McGreal, E. P.et al. 2010. Inactivation of IL-6 and soluble IL-6 receptor by neutrophil derived serine proteases in cystic fibrosis. Biochimica et Biophysica Acta - Molecular Basis of Disease 1802(7-8), pp. 649-658. (10.1016/j.bbadis.2010.04.005)
• Davies, P. L.et al. 2010. Relationship of proteinases and proteinase inhibitors with microbial presence in chronic lung disease of prematurity. Thorax 65(3), pp. 246-251. (10.1136/thx.2009.116061)
• Poon, C. and Kotecha, S. 2010. Assessment of pulmonary arterial haemodynamics by MRI in children born preterm. Welsh Paediatric Journal 33, pp. 6-8.

2009

• Beeton, M. L.et al. 2009. Concurrent titration and determination of antibiotic resistance in 'ureaplasma' species with identification of novel point mutations in genes associated with resistance. Antimicrobial Agents and Chemotherapy 53(5), pp. 2020-2027. (10.1128/AAC.01349-08)
• Wall, S. R.et al. 2009. The viral aetiology of croup and recurrent croup. Archives of Disease in Childhood 94(5), pp. 359-360. (10.1136/adc.2008.142984)
• Maxwell, N. C., Nuttall, D. and Kotecha, S. 2009. Does Ureaplasma spp. cause chronic lung disease of prematurity: ask the audience?. Early Human Development 85(5), pp. 291-296. (10.1016/j.earlhumdev.2008.12.002)
• Beeton, M. L.et al. 2009. Comparison of full gyrA, gyrB, parC and parE gene sequences between all Ureaplasma parvum and Ureaplasma urealyticum serovars to separate true fluoroquinolone antibiotic resistance mutations from non-resistance polymorphism. Journal of Antimicrobial Chemotherapy 64(3), pp. 529-538. (10.1093/jac/dkp218)
• Joshi, S.et al. 2009. Reproducibility of myocardial velocity and deformation imaging in term and preterm infants. European Journal of Echocardiography 11(1), pp. 44-50. (10.1093/ejechocard/jep161)
• Barbato, A.et al. 2009. Paediatrics in Berlin. European Respiratory Journal 34(2), pp. 436-443. (10.1183/09031936.00038809)
• Pickerd, N. and Kotecha, S. 2009. Pathophysiology of respiratory distress syndrome. Paediatrics and Child Health 19(4), pp. 153-157. (10.1016/j.paed.2008.12.010)

2008

• Kotecha, S. 2008. Chronic lung disease of prematurity. In: McIntosh, N. et al. eds. Forfar & Arneil's textbook of pediatrics. 7th ed. Edinburgh: Churchill Livingstone Elsevier, pp. 727-743.
• Davies, P. L.et al. 2008. Monoclonal anti-neutrophil elastase antibody characterisation: ability to block function, detect free versus serpin-complexed enzyme and stain intracellular granules. Journal of Immunological Methods 336(2), pp. 175-182. (10.1016/j.jim.2008.04.010)
• Miralles, R., Hodge, R. and Kotecha, S. 2008. Fetal cortisol response to intrauterine microbial colonisation identified by the polymerase chain reaction and fetal inflammation. Archives of Disease in Childhood. Fetal and neonatal edition 93(1), pp. F51-F54. (10.1136/adc.2006.110130)

2006

• Greenough, K., Kotecha, S. and Vrijlandt, E. 2006. Bronchopulmonary dysplasia, current models and concepts. In: Frey, U. and Gerritsen, J. eds. Respiratory Diseases in Infants and Children. Respiratory Society Monograph Vol. 37. European Respiratory Society, pp. 217-233., (10.1183/1025448x.00037014)

2004

• Kotecha, S.et al. 2004. Pulmonary Ureaplasma urealyticum is associated with the development of acute lung inflammation and chronic lung disease in preterm infants. Pediatric Research 55(1), pp. 61-8. (10.1203/01.PDR.0000100757.38675.50)

2003

• Kotecha, S.et al. 2003. The role of neutrophil apoptosis in the resolution of acute lung injury in newborn infants. Thorax 58(11), pp. 961-7. (10.1136/thorax.58.11.961)
• Kotecha, S. 2003. Chronic lung disease of prematurity. In: Mackintosh, N., Helms, P. and Smyth, R. eds. Forfar and Arneil Textbook of Paediatrics (6th ed.). Edinburgh: Churchill Livingstone, pp. 793-798.

2001

• Kotecha, S.et al. 2001. Repeatability of cellular constituents and cytokine concentration in fluid obtained by non-bronchoscopic bronchoalveolar lavage of infants receiving extracorporeal oxygenation. Thorax 56(12), pp. 924-31. (10.1136/thorax.56.12.924)
• Currie, A. E.et al. 2001. Epidermal growth factor in the lungs of infants developing chronic lung disease. European Respiratory Journal 18(5), pp. 796-800. (10.1183/09031936.01.00088201)

1999

• Kotecha, S. 1999. Chronic respiratory complications of neonatal disorders. In: Landau, L. I. and Taussig, L. M. eds. Textbook of paediatric respiratory medicine. Mosby, pp. 488-521.

1994

• Kotecha, S., Taylor, I. K. and Shaw, R. J. 1994. Pharmalogical modulation of platlet derived growth factor (B) mRNA expresion in human alveolar macrophages. Pulmonary Pharmacology 7(6), pp. 383-391.
• Taylor, I. K.et al. 1994. Platelet derived growth factor (B) mRNA expression in alveolar macrophages in vivo in human asthma. European Respiratory Journal 7(11), pp. 1966-1972.