Dr Kristin Ladell

2023

• Shepherd, F. R. et al. 2023. The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4+ memory T cells. Communications Biology 6, article number: 78. (10.1038/s42003-023-04420-1)
• Shepherd, F. R. et al. 2023. The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4 + memory T cells. Communications Biology 6(1), article number: 78. (10.1038/s42003-023-04420-1)

2022

• Goncharov, M. et al. 2022. VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2. Nature Methods 19(9), pp. 1017–1019. (10.1038/s41592-022-01578-0)
• Fielding, C. A. et al. 2022. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. eLife 11 (10.7554/eLife.74489)
• Pymm, P. et al. 2022. Epitope length variants balance protective immune responses and viral escape in HIV-1 infection. Cell Reports 38(9), article number: 110449. (10.1016/j.celrep.2022.110449)

2021

• Campion, S. L. et al. 2021. Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial. Journal of Clinical Investigation 131(23), article number: e150823. (10.1172/JCI150823)
• Man, S. et al. 2021. Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells. Journal of Immunology 207(4), pp. 1009-1017. (10.4049/jimmunol.2000756)
• Clement, M. et al. 2021. CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences 118(29), article number: e2019639118. (10.1073/pnas.2019639118)
• Vlachava, V. et al. 2021. Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus. Journal of Clinical Investigation 131(4), article number: e139296. (10.1172/JCI139296)
• Hanna, S. J. et al. 2021. T cell phenotypes in COVID-19 - a living review. Oxford Open Immunology 2(1) (10.1093/oxfimm/iqaa007)

2020

• Galletti, G. et al. 2020. Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans. Nature Immunology 21, pp. 1552-1562. (10.1038/s41590-020-0791-5)
• Kasatskaya, S. A. et al. 2020. Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs. eLife 9, article number: e57063. (10.7554/eLife.57063)
• Ahmed, R. et al. 2020. CD57+ Memory T Cells Proliferate In Vivo. Cell Reports 33(11), article number: 108501. (10.1016/j.celrep.2020.108501)
• Narayanan, G. A. et al. 2020. The MAIT TCRβ chain contributes to discrimination of microbial ligand. Immunology and Cell Biology 98(9), pp. 770-781. (10.1111/imcb.12370)
• Hanna, S. J. et al. 2020. Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype. Diabetologia 63, pp. 1174-1185., article number: Diabetologia volume 63, pages1174–1185(2020). (10.1007/s00125-020-05114-7)
• Pearson, F. E. et al. 2020. Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells. Clinical and Translational Immunology 9 (10.1002/cti2.1141)
• Edwards, S. C. et al. 2020. A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans. Journal of Experimental Medicine 217(5), article number: e20190834. (10.1084/jem.20190834)
• Starke, C. E. et al. 2020. SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues. Journal of Clinical Investigation 130(2), pp. 789-798. (10.1172/JCI129161)
• Brenna, E. et al. 2020. CD4+ T follicular helper cells in human tonsils and blood are clonally convergent but divergent from Non-Tfh CD4+ cells. Cell Reports 30(1), pp. 137-152. (10.1016/j.celrep.2019.12.016)
• Smith, C. J. et al. 2020. Stochastic expansions maintain the clonal stability of CD8+ T cell populations undergoing memory inflation driven by murine cytomegalovirus. Journal of Immunology 204(1), pp. 112-121. (10.4049/jimmunol.1900455)

2019

• Appanna, G. D., Pembroke, T. P. I., Miners, K. L., Price, D. A., Gallimore, A. M., Ladell, K. and Godkin, A. J. 2019. Rituximab depletion of intrahepatic B cells to control refractory hepatic autoimmune overlap syndrome. QJM: An International Journal of Medicine 112(10), pp. 793-795. (10.1093/qjmed/hcz161)
• Meckiff, B. J. et al. 2019. Primary EBV infection induces an acute wave of activated antigen-specific cytotoxic CD4+ T cells. Journal of Immunology 203(3), article number: ji1900377. (10.4049/jimmunol.1900377)
• Wong, E. B. et al. 2019. TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology 2(1), pp. -., article number: 203. (10.1038/s42003-019-0442-2)
• Mohammed, R. N. et al. 2019. ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells. Scientific Reports 9, article number: 5487. (10.1038/s41598-019-41811-z)
• Li, N. et al. 2019. Memory CD4+ T cells are generated in the human fetal intestine. Nature Immunology 20, pp. 301-312. (10.1038/s41590-018-0294-9)
• Mayassi, T. et al. 2019. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Cell 176(5), pp. 967-981.e19. (10.1016/j.cell.2018.12.039)
• McLaren, J. et al. 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202(3), pp. 943-955. (10.4049/jimmunol.1701757)
• Shimauchi, T. et al. 2019. Dendritic cells promote the spread of human T-cell leukemia virus type 1 via bidirectional interactions with CD4+ T cells. Journal of Investigative Dermatology 139(1), pp. 157-166. (10.1016/j.jid.2018.06.188)

2018

• Boelen, L. et al. 2018. Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1. Science Immunology 3(29), article number: eaao2892. (10.1126/sciimmunol.aao2892)
• Powell, W. E. et al. 2018. Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes. Diabetologia 61, pp. 1794-1803. (10.1007/s00125-018-4651-x)
• Pogorelyy, M. V. et al. 2018. Exploring the pre-immune landscape of antigen-specific T cells. Genome Medicine 10, article number: 68. (10.1186/s13073-018-0577-7)
• Costa del Amo, P. et al. 2018. Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness. PLoS Biology 16(6), article number: e2005523. (10.1371/journal.pbio.2005523)
• Wun, K. S. et al. 2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19, pp. 397-406. (10.1038/s41590-018-0065-7)
• Miles, J. J. et al. 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. Journal of Clinical Investigation 128(4), pp. 1569-1580. (10.1172/JCI91512)
• McCully, M. L. et al. 2018. CCR8 expression defines tissue-resident memory T cells in human skin. Journal of Immunology 200(5), pp. 1639-1650. (10.4049/jimmunol.1701377)
• James, E. A. et al. 2018. Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop. Diabetologia 61(3), pp. 658-670. (10.1007/s00125-017-4508-8)
• Culina, S. et al. 2018. Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors. Science Immunology 3(20), article number: eaao4013. (10.1126/sciimmunol.aao4013)
• Shugay, M. et al. 2018. VDJdb: a curated database of T-cell receptor sequences with known antigen specificity. Nucleic Acids Research 46(D1), pp. D419-D427. (10.1093/nar/gkx760)
• Lissina, A. et al. 2018. Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions. Scientific Reports 8(1), article number: 2534. (10.1038/s41598-017-18062-x)

2017

• Van Braeckel-Budimir, N. et al. 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47(5), pp. 835-847.e4. (10.1016/j.immuni.2017.10.013)
• Culshaw, A. et al. 2017. Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response. Nature Immunology 18, pp. 1228-1237. (10.1038/ni.3850)
• Anguille, S. et al. 2017. Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia. Blood 130(15), pp. 1713-1721. (10.1182/blood-2017-04-780155)
• Murrell, I. et al. 2017. The pentameric complex drives immunologically covert cell -cell transmission of wild-type human cytomegalovirus. Proceedings of the National Academy of Sciences 114(23), pp. 6104-6109. (10.1073/pnas.1704809114)
• Davey, M. S. et al. 2017. Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance. Nature Communications 8, article number: 14760. (10.1038/ncomms14760)
• Dockree, T. et al. 2017. CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold. Immunology and Cell Biology 95(1), pp. 68-76. (10.1038/icb.2016.85)

2016

• Ahmed, R. et al. 2016. Human stem cell-like memory T cells are maintained in a state of dynamic flux. Cell Reports 17(11), pp. 2811-2818. (10.1016/j.celrep.2016.11.037)
• Watson, H. A. et al. 2016. Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1. Immunology and Cell Biology 94(8) (10.1038/icb.2016.45)
• Caucheteux, S. M. et al. 2016. Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. Journal of Investigative Dermatology 136(6), pp. 1172-1181. (10.1016/j.jid.2016.01.033)
• Pearson, J. A. et al. 2016. Proinsulin expression shapes the TCR repertoire but fails to control the development of low-avidity insulin-reactive CD8+ T cells. Diabetes 65(6), pp. 1679-1689. (10.2337/db15-1498)
• Du, V. Y. et al. 2016. HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection. The Journal of Immunology 196(8), pp. 3276-3286. (10.4049/jimmunol.1502411)
• Ridley, A. et al. 2016. Activation-induced killer cell immunoglobulin-like receptor 3DL2 binding to HLA-B27 licenses pathogenic T cell differentiation in spondyloarthritis. Arthritis and Rheumatology 68(4), pp. 901-914. (10.1002/art.39515)

2015

• Holland, C. J. et al. 2015. Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers. Journal of Immunology 195(12), pp. 5827-5836. (10.4049/jimmunol.1402787)
• Ladell, K. et al. 2015. Continuous antigenic stimulation of DO11.10 TCR transgenic mice in the presence or absence of IL-1: possible implications for mechanisms of T cell depletion in HIV disease. Journal of Immunology 195(9), pp. 4096-4105. (10.4049/jimmunol.1500799)
• Colbeck, E. et al. 2015. Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors. Oncotarget 6(28), pp. 24649-24659. (10.18632/oncotarget.5584)
• Neller, M. A. et al. 2015. Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics. Immunology and Cell Biology 93, pp. 625-633. (10.1038/icb.2015.17)
• Petersen, J. et al. 2015. Determinants of gliadin-specific T cell selection in celiac disease. The Journal of Immunology 194(12), pp. 6112-6122. (10.4049/jimmunol.1500161)
• Kloverpris, H. N. et al. 2015. CD8+ TCR bias and immunodominance in HIV-1 infection. The Journal of Immunology 194(11), pp. 5329-5345. (10.4049/jimmunol.1400854)
• Roberto, A. et al. 2015. Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation. Blood 125(18), pp. 2855-2864. (10.1182/blood-2014-11-608406)
• Skowera, A. et al. 2015. β-Cell-specific CD8 T Cell phenotype in Type 1 diabetes reflects chronic autoantigen exposure. Diabetes 64(3), pp. 916-925. (10.2337/db14-0332)
• Parkinson, N. J. et al. 2015. Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes. Genome Research 25(2), pp. 226-234. (10.1101/gr.179770.114)
• Costa, A. I. et al. 2015. Complex T-cell receptor repertoire dynamics underlie the CD8+T-cell response to HIV-1. Journal of Virology 89(1), pp. 110-119. (10.1128/JVI.01765-14)

2014

• Willis, G. R. et al. 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29(12), pp. 2756-2763. (10.1093/humrep/deu281)
• Tan, M. et al. 2014. T cell receptor binding affinity governs the functional profile of cancer-specific CD8+T cells. Clinical and Experimental Immunology 180(2), pp. 255-270. (10.1111/cei.12570)
• Pearson, J., Thayer, T. C., McLaren, J. E., Miners, K. L., Ladell, K. I., Price, D. and Wong, F. S. 2014. Analysis of the repertoire of insulin-reactive CD8(+) T cells [Abstract]. Immunology 143(S2), pp. 152-152. (10.1111/imm.12406)
• Connolly, K. D. et al. 2014. Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. Journal of Lipid Research 55, pp. 2064-2072. (10.1194/jlr.M049726)
• Taylor, G. S. et al. 2014. A recombinant modified vaccinia Ankara vaccine encoding Epstein-Barr virus (EBV) target antigens: a phase I trial in UK patients with EBV-positive cancer. Clinical Cancer Research 20(19), pp. 5009-5022. (10.1158/1078-0432.CCR-14-1122-T)
• Bengsch, B. et al. 2014. Identification of a TSCM phenotype HCV-specific CD8+T cell response with superior functionality in chronic HCV infection [Abstract]. Hepatology 60, pp. 1071A-1072A., article number: 1815.
• Kløverpris, H. N. et al. 2014. Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load. AIDS 28(14), pp. 2007-2021. (10.1097/QAD.0000000000000362)
• Gold, M. C. et al. 2014. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. Journal of Experimental Medicine 211(8), pp. 1601-1610. (10.1084/jem.20140507)
• Dolton, G. M. et al. 2014. Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells. Clinical and Experimental Immunology 177(1), pp. 47-63. (10.1111/cei.12339)
• Ondondo, B. et al. 2014. Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cellsviablood vessels and lymphatics. International Journal of Cancer 134(9), pp. 2156-2167. (10.1002/ijc.28556)
• Melamed, A. et al. 2014. Clonality of HTLV-2 in natural infection. PLoS Pathogens 10(3), pp. e1004006. (10.1371/journal.ppat.1004006)
• Bridgeman, J. S., Ladell, K. I., Sheard, V. E., Miners, K. L., Hawkins, R. E., Price, D. and Gilham, D. E. 2014. CD3ζ-based chimeric antigen receptors mediate T cell activation viacis- andtrans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy. Clinical and Experimental Immunology 175(2), pp. 258-267. (10.1111/cei.12216)
• Lissina, A. et al. 2014. The link between CD8+ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate. AIDS 28(4), pp. 477-486. (10.1097/QAD.0000000000000175)

2013

• Bernasconi, M. et al. 2013. Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases. International Journal of Cancer 133(10), pp. 2341-2350. (10.1002/ijc.28239)
• Scurr, M. J. et al. 2013. Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3- T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells. Mucosal Immunology n/a (10.1038/mi.2013.62)
• van den Berg, H. A. et al. 2013. Cellular-level versus receptor-level response threshold hierarchies in T-cell activation. Frontiers in Immunology 4, article number: 250. (10.3389/fimmu.2013.00250)
• Ladell, K. I. et al. 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38(3), pp. 425-436. (10.1016/j.immuni.2012.11.021)
• Koning, D. et al. 2013. CD8+ TCR repertoire formation is guided primarily by the peptide component of the antigenic complex. The Journal of Immunology 190(3), pp. 931-939. (10.4049/jimmunol.1202466)
• Chattopadhyay, P. et al. 2013. Holoendemic malaria exposure is associated with altered epstein-barr virus-specific CD8+ T-cell differentiation. Journal of Virology 87(3), pp. 1779-1788. (10.1128/JVI.02158-12)
• Ladell, K. I. 2013. Antigen-specific T cell turnover and expansion in vivo during chronic immune stimulation. PhD Thesis, Cardiff University.

2012

• Humphreys, I. R. et al. 2012. Avidity of influenza-specific memory CD8+T-cell populations decays over time compromising antiviral immunity. European Journal of Immunology 42(12), pp. 3235-3242. (10.1002/eji.201242575)
• McCully, M. L., Ladell, K. I., Hakobyan, S., Mansel, R. E., Price, D. and Moser, B. 2012. Epidermis instructs skin homing receptor expression in human T cells. Blood 120(23), pp. 4591-4598. (10.1182/blood-2012-05-433037)
• Hindley, J. P. et al. 2012. T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T cell depletion. Cancer Research 72(21), pp. 5473-5482. (10.1158/0008-5472.CAN-12-1912)
• Ekeruche, J. et al. 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287(44), pp. 37269-37281. (10.1074/jbc.M112.386409)
• Ekeruche-Makinde, J. et al. 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287(44), pp. 37269-37281. (10.1074/jbc.M112.386409)
• Liddy, N. et al. 2012. Monoclonal TCR-redirected tumor cell killing. Nature Medicine 18(6), pp. 980-987. (10.1038/nm.2764)
• Cole, D. et al. 2012. Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4+ T-cell repertoire selection. Nature Communications 3, article number: 665. (10.1038/ncomms1665)
• Doherty, T. M. et al. 2012. A T Cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years. PLoS ONE 7(10), article number: e48322. (10.1371/journal.pone.0048322)

2011

• Clement, M. et al. 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187(2), pp. 654-663. (10.4049/jimmunol.1003941)
• Kreutzman, A. et al. 2011. Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation. Leukemia 25(10), pp. 1587-1597. (10.1038/leu.2011.135)
• Hindley, J. P. et al. 2011. Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors. Cancer Research 71(3), pp. 736-746. (10.1158/0008-5472.CAN-10-1797)

2010

• van Bockel, D. J. et al. 2010. Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response. The Journal of Immunology 186(1), pp. 359-371. (10.4049/jimmunol.1001807)
• Jones, M. et al. 2010. IL-10 restricts memory T cell inflation during cytomegalovirus infection. The Journal of Immunology 185(6), pp. 3583-3592. (10.4049/jimmunol.1001535)
• Cole, D. et al. 2010. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. The Journal of Immunology 185(4), pp. 2600-2610. (10.4049/jimmunol.1000629)
• Wooldridge, L. et al. 2010. MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. Journal of Immunology 184(7), pp. 3357-3366. (10.4049/jimmunol.0902398)
• Van Tendeloo, V. F. et al. 2010. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proceedings of the National Academy of Sciences of the United States of America 107(31), pp. 13824-13829. (10.1073/pnas.1008051107)
• Harris, L. D. et al. 2010. Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques. Blood 116(20), pp. 4148-4157. (10.1182/blood-2010-05-283549)
• Subramanya, S. et al. 2010. Enhanced induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic cell-targeted delivery of SOCS-1 siRNA. Molecular Therapy 18(11), pp. 2028-2037. (10.1038/mt.2010.148)

2009

• Melenhorst, J. J. et al. 2009. High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow. Blood 113(10), pp. 2238-2244. (10.1182/blood-2008-04-151969)
• Lissina, A. et al. 2009. Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. Journal of Immunological Methods 340(1), pp. 11-24. (10.1016/j.jim.2008.09.014)

2008

• Venturi, V. et al. 2008. TCR β-Chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV. Journal of Immunology 181(11), pp. 7853-7862. (10.4049/​jimmunol.181.11.7853)
• Chattopadhyay, P. K. et al. 2008. Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+T cells with peptide-major histocompatibility complex class I tetramers. Cytometry Part A 73A(11), pp. 1001-1009. (10.1002/cyto.a.20642)
• Ladell, K. I., Hellerstein, M. K., Cesar, D., Busch, R., Boban, D. and McCune, J. M. 2008. Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression. The Journal of Immunology 180(12), pp. 7907-7918. (10.4049/jimmunol.180.12.7907)

2007

• Ladell, K. et al. 2007. Immune activation suppresses initiation of lytic Epstein-Barr virus infection. Cellular Microbiology 9(8), pp. 2055. (10.1111/j.1462-5822.2007.00937.x)

2004

• Giger, B. et al. 2004. Human tonsillar tissue block cultures differ from autologous tonsillar cell suspension cultures in lymphocyte subset activation and cytokine gene expression. Journal of Immunological Methods 289(1-2), pp. 179-190. (10.1016/j.jim.2004.04.015)
• Keyser, J., Schultz, J., Ladell, K. I., Elzaouk, L., Heinzerling, L., Pavlovic, J. and Moelling, K. 2004. IP-10-encoding plasmid DNA therapy exhibits anti-tumor and anti-metastatic efficiency. Experimental Dermatology 13(6), pp. 380-390. (10.1111/j.0906-6705.2004.00191.x)

2003

• Ladell, K. I., Heinrich, J., Schweneker, M. and Moelling, K. 2003. A combination of plasmid DNAs encoding murine fetal liver kinase 1 extracellular domain, murine interleukin-12, and murine interferon-y inducible protein-10 leads to tumor regression and survival in melanoma-bearing mice. Journal of Molecular Medicine 81(4), pp. 271-278. (10.1007/s00109-003-0425-z)