Yr Athro Matthias Eberl

Bywgraffiad

Anrhydeddau a Dyfarniadau

• 2015: Promotion to Reader, Cardiff University
• 2011: Promotion to Senior Lecturer, Cardiff University
• 2009: Best Free Communications Prize at 9th European Peritoneal Dialysis Meeting, Strasbourg, France
• 2007: RCUK Fellowship in Translational Research in Experimental Medicine
• 2007: Wellcome Trust 'VIP' Award
• 1995: PhD Studentship, "Graduiertenkolleg Molekulare Biologie und Pharmakologie", German Research Foundation (DFG)

Aelodaethau proffesiynol

Ymrwymiadau siarad cyhoeddus

Pwyllgorau ac adolygu

• since 08/2015: Engagement Lead, Systems Immunity Research Institute
• since 04/2014: Chair of PhD Appraisal Panel, Infection & Immunity
• since 05/2011: Founder and Administrator, γδ T Cell Forum
• since 11/2009: Web Editor, Infection & Immunity

Reviewer experience

Funding bodies

• AERES - Evaluation Agency for Research and Higher Education, France
• Barts and The London Charity
• BBSRC - Biotechnology and Biological Sciences Research Council
• Cancer Research UK
• Crohn’s in Childhood Research Association (CICRA)
• Crohn's and Colitis UK
• European Research Council (ERC)
• Fondation pour la Recherche Médicale, France
• German-Israeli Foundation for Scientific Research and Development
• Institut National du Cancer (INCa), France
• Kay Kendall Leukaemia Fund
• Kidney Research UK
• King’s Health Partners R&D Challenge Fund
• MRC - Medical Research Council
• Ministry of Science, Technology and Space, Israel
• Multiple Sclerosis Society, UK
• Research Grants Council, Hong Kong
• Wellcome Trust
• Wilhelm Sander Foundation, Germany

PhD examiner

• Cardiff University
• King's College London
• National University of Ireland, Maynooth
• University of Lisbon, Portugal
• University of Palermo, Italy
• Medical University of Vienna, Austria
• University of Bordeaux, France

International journals

• American Journal of Physiology – Renal Physiology
• Blood
• Bone
• BMC Immunology
• Breast Cancer Research
• Cancer Immunology Immunotherapy
• Cancer Research
• Carcinogenesis
• Cell Biochemistry & Function
• Cellular Immunology
• Chronobiology International
• Clinical Cancer Research
• Clinical and Developmental Immunology
• Clinical and Experimental Immunology
• Clinical and Experimental Medicine
• Current Cancer Drug Targets
• Current Immunology Reviews
• Cytokine
  
• EMBO Reports
• European Journal of Immunology
• Experimental Parasitology
• FASEB Journal
• FEBS Journal
• Frontiers in Immunology
• Haematologica
• Human Immunology
• Immunology
• Immunology and Cell Biology
• Immunology Letters
• Infection and Immunity
• International Immunology
• International Journal of Artificial Organs
• International Journal of Immunogenetics
• International Urology and Nephrology
• Journal of the American Chemical Society
• Journal of the American Society of Nephrology
  
• Journal of Biological Chemistry
• Journal of Biological Regulators and Homeostatic Agents
• Journal of Clinical Investigation
• Journal of Immunology
• Journal of Infectious Diseases
• Journal of Leukocyte Biology
• Journal of Medicinal Chemistry
• Journal of Molecular Medicine
• Journal of Translational Medicine
• Kidney International
• Microbes and Infection
• Molecular Immunology
• Mucosal Immunology
• Nephrology, Dialysis, Transplantation
• OncoImmunology
• Oncology Reviews
• Parasite Immunology
• Peritoneal Dialysis International
• PLoS ONE
• PLoS Pathogens
• Science Translational Medicine
• Scientific Reports
  
• Trends in Immunology
• Trends in Parasitology

Cyhoeddiadau

• Date
• Type
• Selected

Addysgu

Teaching

In order to overcome the awe-inspiring complexity of the immune system and press it into digestible portions, immunology teaching is often in the danger to over-simplify scenarios and/or follow temporary fashions.  The main challenges are to keep up abreast with the latest literature and incorporate recent advances into the lessons; to transport one’s own enthusiasm for science to the students; to demonstrate that even the most complex mechanisms can be of enormous clinical relevance in health and disease; and to confront students with standard methods in diagnostic and research labs, but also to make them aware of the possibilities of modern technology.  My goal is to educate open-minded and critical students that are provided with all the scientific but also interpersonal tools required for being capable of questioning contemporary points of view and solving new problems.

Undergraduate teaching

I have been participating in the Year 2 SSC module “Interactive Immunology” for eight consecutive years, which comprises lectures, student lab paracticals and an assessment of student presentations. From 2017 on I will be lecturing in a new module on Biomarkers and Diagnostics developments.

I have trained undergraduate summer students as well as internship and Erasmus students.

Since 2010 I have acted as Personal Tutor for Medicine students, since 2013 as Academic Mentor. 

Postgraduate teaching

I have supervised or co-supervised more than ten PhD students, all of whom completed, or are on course to complete, their PhD within four years. 

I serve as Chair of approx. 20 appraisal panels for PhD and MD students per year, and have been appointed as internal examiner or viva chair of PhD theses at Cardiff University and as external examiner of PhD theses in the UK, Ireland, Italy and Portugal.

Public engagement and involvement

As Engagement Lead and member of the Steering Group of the Systems Immunity Research Institute, I aim to reach out to all stake-holders and engage with patients, health care providers, schools, policy makers, media, funding bodies and industry, and have set up a Lay Faculty of members of the public who help us reach our goals.

Supervision

Goruchwyliaeth gyfredol

Past projects

PhD – Chris J Tyler
"Control of CD4+ T cell responses by γδ T-APCs"
Supervisor (Co-supervisor: Prof. Bernhard Moser)
Awarded in 2016

PhD – Anna Rita Liuzzi
"Unconventional T-cell driven inflammatory responses during acute peritonitis: implications for diagnosis and therapy of peritoneal dialysis patients"
Supervisor (Co-supervisor: Dr. Tim Bowen)
Awarded in 2015

PhD – Hung-Chang Chen
"Human γδ T cell-based immune therapy for breast cancer"
Supervisor (Co-supervisor: Dr. Richard Clarkson)
Awarded in 2015

PhD – Matt P Morgan
"Immune fingerprinting in acute severe sepsis"
Co-supervisor (Supervisor: Prof. Judith Hall)
Awarded in 2014

PhD – Luke Piggott
"Investigating the therapeutic potential of cellular FLICE-like inhibitory protein and TRAIL in preclinical models of breast cancer"
Co-supervisor (Supervisor: Dr. Richard Clarkson)
Awarded in 2012

PhD – Chan-Yu Lin
"The role of γδ T cells in peritoneal dialysis-associated bacterial infection"
Supervisor (Co-supervisor: Prof. Nicholas Topley)
Awarded in 2012

PhD – Martin S Davey
"Cellular crosstalk of human Vγ9/Vδ2 T cells, neutrophils and monocytes in response to bacterial infections"      
Supervisor (Co-supervisor: Prof. Bernhard Moser)
Awarded in 2012

PhD – Raj R Bansal
"B cell help provided by human γδ T cells"
Supervisor (Co-supervisor: Prof. Bernhard Moser)
Awarded in 2012

Ymgysyllty

I am passionate about engaging and involving the public in my research and disseminate relevant findings to specialist and lay audiences.

As Engagement Lead of the Systems Immunity Research Institute, I conceive, oversee and coordinate a wide range of engagement and involvement activities, and aim to reach out to all stake-holders in our research - patients, health care providers, schools, policy makers, media, funders, industry and the general public.

I established and chair a Lay Faculty for the Systems Immunity Research Institute consisting of members of the public who provide valuable feedback on research proposals, study protocols, consent forms, news items and press releases, and help foster a close dialogue between local scientists and the wider public. This Lay Faculty has developed into a flagship involvement activity at Cardiff University and has received very positive feedback from Health and Care Research Wales and the Wellcome Trust.

In addition to facilitating and promoting engagement activities by colleagues across the Systems Immunity Research Institute and the College of Biomedical and Life Sciences, over the past 3 years I directly developed and contributed to activities such as 1) showcasing Cardiff research twice at Techniquest, the local Science museum; 2) promoting the importance of international research and collaboration for Cardiff University, Wales and the UK at receptions in the National Assembly for Wales and the House of Commons; 3) hosting the MP for Cardiff Central, Jo Stevens, at the Annual Infection & Immunity Meeting 2017; 4) creating educational computer games for primary schools; 5) developing a Welsh-medium philosophy/immunology workshop for primary school children; 6) establishing contacts with Radio Glamorgan, the local hospital radio station; 7) designing a Cardiff-wide bus stop poster campaign; 8) running a university-wide picture/artwork competition; 9) celebrating diversity and equality across Infection & Immunity, the School of Medicine and the University as a whole, and promoting the importance of international collaboration and training for local research and innovation; and 10) collaborating with BBC Wales on a programme about sepsis involving BBC weatherman Derek Brockway, and on sourcing laboratory equipment and props for the Dr Who Christmas Special 2014.

As Web Editor of the Systems Immunity URI (and its predecessors, the i3-IRG and the Institute of Infection & Immunity, since 2009), I have substantially improved the visibility of local research, teaching, innovation and engagement, accompanied by successful social media accounts (>1,600 Twitter followers). I also created an interactive ‘γδ T cell Forum’, which has >1,000 followers from >50 countries and has developed into a key networking resource in the field. 

Through my participation in the core activities of the British Society for Immunology (BSI), the largest immunological society in Europe, I directly promote immunology-related research, public engagement and education in Wales, the UK and beyond. I was elected as BSI Trustee in 2017, after serving two terms as Regional Representative for Wales on the BSI Forum (2010-2016), the Society’s ‘think tank’. As one of only 12 Trustees, I am directly responsible for the effective operation of the Society, with regard to finance, governance, strategy and supervision of its CEO. As Chairman of the BSI South Wales regional group (2007-2015), I established Cardiff as one of the most active and visible regional groups in the UK, increased its annual budget eight-fold, and created the prestigious annual Jonathan Boulter Memorial Lecture given by the leading immunologists in the world.