Targeting Metastasis
Mae'r cynnwys hwn ar gael yn Saesneg yn unig.
The Clarkson group focuses on identifying novel therapeutic strategies to eliminate or modify the cancer cells responsible for the spread of tumours around the body.
According to the cancer stem cell hypothesis, only a limited proportion of tumour cells with stem-like properties are capable of seeding new tumours at distal sites. These cells also appear to be highly adaptable and are resistant to conventional therapeutic agents.
Using breast and prostate cancer as their principal platforms, the Clarkson lab aims to understand the mechanisms of this cellular plasticity and drug resistance in order to identify new therapeutic strategies to target this minority cell population within cancers.