Cyhoeddiadau academaidd
Fel yr unig sefydliad yn Ewrop sydd wedi ei neilltuo ar gyfer ymchwilio i bôn-gelloedd cancr, mae gwaith ein ymchwilwyr yn cael ei gyhoeddi'n reolaidd.
Ar y dudalen hon, fe ddewch chi o hyd i restr o erthyglau a phapurau diweddar a fydd, gobeithio, yn ddefnyddiol i chi. Nodwch bod y cynnwys isod yn Saesneg.
2023
- Edmunds, G., Beck, S., Umakant Kale, K., Spasic, I., O'Neill, D., Brodbelt, D. and Smalley, M. J. 2023. Associations between dog breed and clinical features of mammary epithelial neoplasia in bitches: an epidemiological study of submissions to a single diagnostic pathology centre between 2008-2021. Journal of Mammary Gland Biology and Neoplasia 28(6) (10.1007/s10911-023-09531-3)
- Michael, D., Kerry-Smith, J., Webberley, T., Murphy, K., Plummer, S., Parry, L. and Marchesi, J. 2023. Does flow culture impact upon gut-probiotic interactions: a comparison with static culture. Journal of Functional Foods
- Shorning, B., Trent, N., Griffiths, D. F., Worzfeld, T., Offermanns, S., Smalley, M. J. and Williamson, M. 2023. Plexin-B1 mutation drives metastasis in prostate cancer mouse models. Cancer Research Communications 3(3), pp. 444-458. (10.1158/2767-9764.CRC-22-0480)
2022
- May, S. et al. 2022. Modification of diet to reduce the stemness and tumourigenicity of murine and human intestinal cells. Molecular Nutrition & Food Research 66(19), article number: 2200234. (10.1002/mnfr.202200234)
- Owen, J. S., Clayton, A. and Pearson, H. B. 2022. Cancer-associated fibroblast heterogeneity, activation and function: implications for prostate cancer. Biomolecules 13(1), article number: 67. (10.3390/biom13010067)
2021
- Abdelfattah, A. M. et al. 2021. Gata2 haploinsufficiency promotes proliferation and functional decline of HSCs with myeloid bias during aging. Blood Advances 5(20), pp. 4285-4290. (10.1182/bloodadvances.2021004726)
- Almotiri, A. et al. 2021. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. Journal of Clinical Investigation 131(1), article number: e129115. (10.1172/JCI129115)
- Dimitriou, P., Li, J., Tornillo, G., McCloy, T. and Barrow, D. 2021. Droplet microfluidics for tumor drug-related studies and programmable artificial cells. Global Challenges 5(7), article number: 2000123. (10.1002/gch2.202000123)
- Edmunds, G. L. et al. 2021. Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine Medicine and Genetics 8, article number: 2. (10.1186/s40575-021-00100-7)
- Gupta, B. et al. 2021. The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus. Cell Reports 36(8), article number: 109588. (10.1016/j.celrep.2021.109588)
- Jukes, Z. et al. 2021. Lipid profiling of mouse intestinal organoids for studying APC mutations. Bioscience Reports 41(3), article number: BSR20202915. (10.1042/BSR20202915)
- Kermanizadeh, A., Jacobsen, N. R., Murphy, F., Parry, L., Zhang, H. and Møller, P. 2021. A review of the current state of nanomedicines for targeting and treatment of cancers - achievements and future challenges. Advanced Therapeutics 4(2), article number: 2000186. (10.1002/adtp.202000186)
- Lawson, H. et al. 2021. JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells. Blood Advances 5(3), pp. 889-899. (10.1182/bloodadvances.2020002702)
- Lawson, H. et al. 2021. CITED2 coordinates key haematopoietic regulatory pathways to maintain the HSC pool in both steady-state haematopoiesis and transplantation. Stem Cell Reports 16(11), pp. 2784-2797. (10.1016/j.stemcr.2021.10.001)
- Mian, S. A., Dos Anjos-Afonso, F. and Bonnet, D. 2021. Advances in human immune system mouse models for studying human hematopoiesis and cancer immunotherapy. Frontiers in Immunology 11, article number: 619236. (10.3389/fimmu.2020.619236)
- Ordonez, L. D. et al. 2021. Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model. Disease Models and Mechanisms 14(5), article number: dmm048736. (10.1242/dmm.048736)
- Stott, K. J., Phillips, B., Parry, L. and May, S. 2021. Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer. Bioscience Reports 41(7), article number: BSR20204113. (10.1042/BSR20204113)
- Tran, B. M., Flanagan, D. J., Phesse, T. J., Vincan, E. and Phesse, T. 2021. Frizzled7 activates β-catenin-dependent and β-catenin-independent Wnt signalling pathways during developmental morphogenesis: implications for therapeutic targeting in colorectal cancer. In: Handbook of Experimental Pharmacology.
2020
- Badder, L. M. et al. 2020. 3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors. PLoS ONE 15(8), article number: e0235319. (10.1371/journal.pone.0235319)
- Jardé, T. et al. 2020. Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium. Cell Stem Cell 27(4), pp. 646-662.E7., article number: VOLUME 27, ISSUE 4, P646-662.E7, OCTOBER 01, 2020. (10.1016/j.stem.2020.06.021)
- Kiraga, L. et al. 2020. Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice. International Journal of Molecular Sciences 21(14), article number: 4991. (10.3390/ijms21144991)
- Koushyar, S., Powell, A. G., Vincan, E. and Phesse, T. J. 2020. Targeting Wnt signaling for the treatment of gastric cancer. International Journal of Molecular Sciences 21(11), article number: 3927. (10.3390/ijms21113927)
- May, S., McDermott, G., Marchesi, J. and Parry, L. 2020. Impact of black raspberries on the normal and malignant Apc deficient murine gut microbiome. Journal of Berry Research 10(1), pp. 61-76. (10.3233/JBR-180372)
- May, S., Parry, C. and Parry, L. 2020. Berry chemoprevention: do berries decrease the window of opportunity for tumourigenesis. Food Frontiers 1(3) (10.1002/fft2.32)
- Queiroz, C. J. et al. 2020. NAP1L1: a novel human colorectal cancer biomarker derived from animal models of Apc inactivation. Frontiers in Oncology 10, article number: 1565. (10.3389/fonc.2020.01565)
- Regan, J. L. and Smalley, M. J. 2020. Integrating single-cell RNA-sequencing and functional assays to decipher mammary cell states and lineage hierarchies. NPJ Breast Cancer 6, article number: 32. (10.1038/s41523-020-00175-8)
- Shorning, B. Y., Dass, M. S., Smalley, M. J. and Pearson, H. B. 2020. The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT signaling. International Journal of Molecular Sciences 21(12), article number: 4507. (10.3390/ijms21124507)
- Tran, B. M. et al. 2020. The hepatitis B virus pre-core protein p22 activates Wnt sgnaling. Cancers 12(6), article number: 1435. (10.3390/cancers12061435)
- Turnham, D. J., Yang, W. W., Davies, J., Varnava, A., Ridley, A. J., Conlan, R. S. and Clarkson, R. W. E. 2020. Bcl-3 promotes multi-modal tumour cell migration via NF-kB1 mediated regulation of Cdc42. Carcinogenesis 41(10), pp. 1432-1443. (10.1093/carcin/bgaa005)
2019
- Flanagan, D. J., Vincan, E. and Phesse, T. J. 2019. Wnt signaling in cancer: not a binary ON:OFF switch. Cancer Research (10.1158/0008-5472.CAN-19-1362)
- French, R. and Tornillo, G. 2019. Heterogeneity of mammary stem cells. Advances in Experimental Medicine and Biology 1169, pp. 119-140. (10.1007/978-3-030-24108-7_7)
- Jimenez-Pascual, A. and Siebzehnrubl, F. A. 2019. Fibroblast growth factor receptor functions in glioblastoma. Cells 8(7), article number: 715. (10.3390/cells8070715)
- Kannen, V., Parry, L. and Martin, F. L. 2019. Phages enter the fight against colorectal cancer. Trends in Cancer 5(10), pp. 577-579. (10.1016/j.trecan.2019.08.002)
- Menendez Gonzalez, J. B. et al. 2019. Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. Scientific Reports 9, article number: 12212. (10.1038/s41598-019-48589-0)
- Mohamed, N., Hay, T., Reed, K. R., Smalley, M. J. and Clarke, A. R. 2019. APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression. BMC Cancer 19, article number: 677. (10.1186/s12885-019-5867-y)
- Young, M. A., May, S., Damo, A., Yoon, Y. S., Hur, M., Swat, W. and Parry, L. 2019. Epigenetic regulation of Dlg1, via Kaiso, alters mitotic spindle polarity and promotes intestinal tumourigenesis. Molecular Cancer Research 17(3), pp. 686-696. (10.1158/1541-7786.MCR-18-0280)
2018
- Burke, Z. D., Reed, K. R., Yeh, S., Meniel, V. S., Sansom, O. J., Clarke, A. R. and Tosh, D. 2018. Spatiotemporal regulation of liver development by the Wnt/β- catenin pathway. Scientific Reports 8, article number: 2735. (10.1038/s41598-018-20888-y)
- Flanagan, D., Austin, C., Vincan, E. and Phesse, T. 2018. Wnt Signalling in gastrointestinal epithelial stem cells. Genes 9(4), article number: 178. (10.3390/genes9040178)
- Greenow, K. R., Zverev, M., May, S., Kendrick, H., Williams, G. T., Phesse, T. and Parry, L. 2018. Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis. Oncotarget 9(92), pp. 36430-36443. (10.18632/oncotarget.26335)
- Hill, W. 2018. Heterotypic cell-cell interactions between KrasG12D cells and normal neighbours in early pancreatic cancer. PhD Thesis, Cardiff University.
- Hoang-Minh, L. B. et al. 2018. Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. EMBO Journal 37(23), article number: e98772. (10.15252/embj.201798772)
- May, S. et al. 2018. Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation. Journal of Pathology 245(3), pp. 270-282. (10.1002/path.5074)
- Morgan, H. 2018. Elucidating the role of TGFβ signalling in drug resistant Hh driven cancers. PhD Thesis, Cardiff University.
- Pearson, H. B. et al. 2018. Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth. Cancer Discovery 8(6), pp. 764-779. (10.1158/2159-8290.CD-17-0867)
- Piggott, L. et al. 2018. Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through post-translational downregulation of c-FLIP. Clinical Cancer Research 24(10), pp. 2452-2463. (10.1158/1078-0432.CCR-17-1381)
- Prim Padilha, A. 2018. Molecular and functional characterization of the role of Foxp3+ regulatory T (Treg) cells in the development of intestinal cancer. PhD Thesis, Cardiff University.
- Puig Barbe, A. 2018. A network of bHLH factors controls self-renewal and bipotential differentiation in the Drosophila intestine. PhD Thesis, Cardiff University.
- Siebzehnrubl, F. A. et al. 2018. Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition. Proceedings of the National Academy of Sciences 115(37), pp. E8765-E8774. (10.1073/pnas.1807962115)
- Tornillo, G. et al. 2018. Dual mechanisms of LYN kinase dysregulation drive aggressive behaviour in breast cancer cells. Cell Reports 25(13), pp. 3674-3692. (10.1016/j.celrep.2018.11.103)
- Vincan, E., Schwab, R. H., Flanagan, D. J., Moselen, J. M., Tran, B. M., Barker, N. and Phesse, T. 2018. The central role of Wnt signaling and organoid technology in personalizing anticancer therapy. Progress in Molecular Biology and Translational Science 153, pp. 299-319. (10.1016/bs.pmbts.2017.11.009)
2017
- Badder, L. 2017. Developing stem-cell containing organoids as a pre-clinical model for colorectal cancer therapeutics. PhD Thesis, Cardiff University.
- Berenjeno, I. M. et al. 2017. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications 8(1), article number: 1773. (10.1038/s41467-017-02002-4)
- Flanagan, D. J., Barker, N., Nowell, C., Clevers, H., Ernst, M., Phesse, T. J. and Vincan, E. 2017. Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo. Disease Models and Mechanisms 10(8), pp. 971-980. (10.1242/dmm.029876)
- Hwang, H. S., Parfitt, G. J., Brown, D. J. and Jester, J. V. 2017. Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD). Experimental Eye Research 163, pp. 37-45. (10.1016/j.exer.2017.02.008)
- Konstantinou, M. 2017. Characterising In-111-anti-γH2AX-TAT in targeting the DNA damage signal associated with Wnt activated colorectal cancer. PhD Thesis, Cardiff University.
- Lanfredini, S. et al. 2017. HPV8 field cancerization in a transgenic mouse model is due to Lrig1+Keratinocyte stem cell expansion. Journal of Investigative Dermatology 137(10), pp. 2208-2216. (10.1016/j.jid.2017.04.039)
- May, S., Evans, S. and Parry, L. 2017. Organoids, organs-on-chips and other systems, and microbiota. Emerging Topics in Life Sciences 1(4), pp. 385-400. (10.1042/ETLS20170047)
- Menendez Gonzalez, J. B. 2017. Exploring the role of GATA2 in normal and malignant haematopoiesis. PhD Thesis, Cardiff University.
- Mohamed, N. 2017. Characterizing the roles of APC2 protein in ovarian homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
- Planells-Palop, V. et al. 2017. Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Molecular Cancer 16, article number: 84. (10.1186/s12943-017-0653-4)
- Yeo, S. K., French, R., Filomena, S. and Clarkson, R. 2017. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment 162(3), pp. 465-477. (10.1007/s10549-017-4149-0)
2016
- Abraham, T. et al. 2016. Ellipsoid segmentation model for analyzing light-attenuated 3D confocal image stacks of fluorescent multi-cellular spheroids. PLoS ONE 11(6), article number: e0156942. (10.1371/journal.pone.0156942)
- Estrada, M. F. et al. 2016. Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression. Biomaterials 78, pp. 50-61. (10.1016/j.biomaterials.2015.11.030)
- Fang, H. Y., Martinez-Arias, A. and De Navascues Melero, J. 2016. Autocrine and paracrine Wingless signalling in the Drosophila midgut by both continuous gradient and asynchronous bursts of wingless expression. F1000Research 5, article number: 317. (10.12688/f1000research.8170.1)
- Flanagan, D. J., Schwab, R. H. M., Tran, B. M., Phesse, T. J. and Vincan, E. 2016. Isolation and culture of adult intestinal, gastric, and lver organoids for cre-recombinase-mediated gene deletion. In: Methods in Molecular Biology. Humana Press, pp. 1-11., (10.1007/7651_2016_14)
- Griessinger, E. et al. 2016. Frequency and dynamics of leukemia-initiating cells during short-term ex vivo culture informs outcomes in acute myeloid leukemia patients. Cancer Research 76(8), pp. 2082-2086. (10.1158/0008-5472.CAN-15-2063)
- Hollins, A. J. and Parry, L. 2016. Long-term culture of intestinal cell progenitors: an overview of their development, application, and associated technologies. Current Pathobiology Reports 4(4), pp. 209-219. (10.1007/s40139-016-0119-1)
- Jurado, J., De Navascues Melero, J. and Gorfinkiel, N. 2016. α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction. Journal of Cell Science, article number: jcs.193268. (10.1242/jcs.193268)
- Parfitt, G. J., Brown, D. J. and Jester, J. V. 2016. Transcriptome analysis of aging mouse meibomian glands. Molecular Vision 22, pp. 518-527.
- Reed, K. R. et al. 2016. Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. Oncotarget 7(32), pp. 51665-51673. (10.18632/oncotarget.10076)
- Togel, L. et al. 2016. Dual targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Molecular Cancer Therapeutics 15(6), pp. 1217-1226. (10.1158/1535-7163.MCT-15-0724)
- Zhao, C. et al. 2016. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nature Communications 7, article number: 10883. (10.1038/ncomms10883)
2015
- Freeman, J. et al. 2015. A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. Molecular Cancer 14, article number: 206. (10.1186/s12943-015-0475-1)
- Huels, D. J. et al. 2015. E-cadherin can limit the transforming properties of activating β‐catenin mutations. EMBO Journal 34(18), pp. 2321-2333. (10.15252/embj.201591739)
- Iglesias, J. M. et al. 2015. Annexin A8 identifies a subpopulation of transiently quiescent c-Kit positive luminal progenitor cells of the ductal mammary epithelium. Plos One 10(3), article number: e0119718. (10.1371/journal.pone.0119718)
- Jester, J. V., Parfitt, G. J. and Brown, D. J. 2015. Meibomian gland dysfunction: hyperkeratinization or atrophy?. BMC Ophthalmology 15(S1), article number: 156. (10.1186/s12886-015-0132-x)
- Leal, M. d. P. C., Sciortino, M., Tornillo, G., Colombo, S., Defilippi, P. and Cabodi, S. 2015. p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis. Gene 562(1), pp. 1-7. (10.1016/j.gene.2015.02.027)
- Lio, K. I. 2015. Characterising the role of Cbx3/HP1γ in normal intestinal homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
- Meniel, V., Megges, M., Young, M., Cole, A., Sansom, O. J. and Clarke, A. R. 2015. Apc and p53 interaction in DNA damage and genomic instability in hepatocytes. Oncogene 34, pp. 4118-4129. (10.1038/onc.2014.342)
- Miraki-Moud, F. et al. 2015. Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo. Blood 125(26), pp. 4060-4068. (10.1182/blood-2014-10-608133)
- Parfitt, G. J., Geyfman, M., Xie, Y. and Jester, J. V. 2015. Characterization of quiescent epithelial cells in mouse meibomian glands and hair follicle/sebaceous glands by immunofluorescence tomography. Journal of Investigative Dermatology 135(4), pp. 1175-1177. (10.1038/jid.2014.484)
- Parfitt, G. J., Kavianpour, B., Wu, K. L., Xie, Y., Brown, D. J. and Jester, J. V. 2015. Immunofluorescence tomography of mouse ocular surface epithelial stem cells and their niche microenvironment. Investigative Ophthalmology & Visual Science 56(12), pp. 7338. (10.1167/iovs.15-18038)
- Parry, L., Young, M., El Marjou, F. and Clarke, A. R. 2015. Protocols for analyzing the role of Paneth cells in regenerating the murine intestine using conditional cre-lox mouse models. Journal of Visualized Experiments(105), article number: e53429. (10.3791/53429)
- Piggott, L., Omidvar, N., Martí Pérez, S., French, R., Eberl, M. and Clarkson, R. W. E. 2015. Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 17(1), pp. 96. (10.1186/s13058-015-0597-9)
- Reed, K. R. et al. 2015. Correction for Reed et al., B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proceedings of the National Academy of Sciences of the United States of America 112(10), pp. E1168. (10.1073/pnas.1502294112)
- Reed, K. R. et al. 2015. Hunk/Mak-v is a negative regulator of intestinal cell proliferation. BMC Cancer 15, article number: 110. (10.1186/s12885-015-1087-2)
- Siebzehnrubl, F. 2015. Application of an RNA amplification method for reliable single-cell transcriptome analysis. Biotechniques 59(3), pp. 137-148. (10.2144/000114331)
- Soady, K. J. et al. 2015. Mouse mammary stem cells express prognostic markers for triple-negative breast cancer. Breast Cancer Research 17, article number: 31. (10.1186/s13058-015-0539-6)
- Tangudu, N. K. et al. 2015. RNA interference using c-Myc-conjugated nanoparticles suppresses breast and colorectal cancer models. Molecular Cancer Therapeutics 14(5), pp. 1259-1269. (10.1158/1535-7163.MCT-14-0970)
2014
- Cowley, M. et al. 2014. Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup. PLoS Biology 12(2), pp. e1001799. (10.1371/journal.pbio.1001799)
- Davies, E. J., Marsh Durban, V., Meniel, V., Williams, G. T. and Clarke, A. R. 2014. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine. The Journal of Pathology 233(1), pp. 27-38. (10.1002/path.4312)
- Greenow, K. R., Clarke, A. R., Williams, G. T. and Jones, R. 2014. Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency. Oncogene 33, pp. 4089-4096. (10.1038/onc.2013.371)
- Hickman, J. A. et al. 2014. Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo. Biotechnology Journal 9(9), pp. 1115-1128. (10.1002/biot.201300492)
- Holik, A. Z., Young, M., Krzystyniak, J., Williams, G. T., Metzger, D., Shorning, B. Y. and Clarke, A. R. 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10(7), article number: e1004453. (10.1371/journal.pgen.1004453)
- Khurana, R. et al. 2014. OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer. BMC Bioinformatics 15(1), pp. 15. (10.1186/1471-2105-15-15)
- Koh, D. -. et al. 2014. KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Proceedings of the National Academy of Sciences of the United States of America 111(42), pp. 15078-15083. (10.1073/pnas.1318780111)
- Krzystyniak, J. 2014. Epigenetic modulation of intestinal homeostasis and tumorigenesis by Brm SWI/SNF chromatin remodelling factor. PhD Thesis, Cardiff University.
- Marsh Durban, V., Jansen, M., Davies, E. J., Morsink, F. H., Offerhaus, G. J. A. and Clarke, A. R. 2014. Epithelial-specific loss of PTEN results in colorectal juvenile polyp formation and invasive cancer. American Journal of Pathology 184(1), pp. 86-91. (10.1016/j.ajpath.2013.10.003)
- Melchor, L. et al. 2014. Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models. Journal of Pathology 233(2), pp. 124-137. (10.1002/path.4345)
- Phesse, T. J. et al. 2014. Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo. Cell Death and Differentiation 21(6), pp. 956-966. (10.1038/cdd.2014.15)
- Sarkisian, M. R. et al. 2014. Detection of primary cilia in human glioblastoma. Journal of Neuro-Oncology 117(1), pp. 15-24. (10.1007/s11060-013-1340-y)
- Suhalim, J. L. et al. 2014. Effect of desiccating stress on mouse meibomian gland function. Ocular Surface 12(1), pp. 59-68. (10.1016/j.jtos.2013.08.002)
- Tanguay, J. S. et al. 2014. Limited stage small cell lung cancer (LS SCLC) South East Wales experience. Lung Cancer 88(Supp 1), pp. S66. (10.1016/S0169-5002(14)70180-1)
- Tornillo, G. and Cabodi, S. 2014. 3D mammary colony-forming cell assay. Bio-Protocol 4(7)
- Vedam-Mai, V. et al. 2014. Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study. PLoS ONE 9(3), article number: e88770. (10.1371/journal.pone.0088770)
2013
- Anjos-Afonso, F., Currie, E., Palmer, H., Foster, K., Taussig, D. and Bonnet, D. 2013. CD34− cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures. Cell Stem Cell 13(2), pp. 161-174. (10.1016/j.stem.2013.05.025)
- Colmont, C. S., Ben Ketah, A., Errington, R. J., Reed, S. H., Udey, M. C. and Patel, G. K. 2013. Human basal cell carcinoma tumor-initiating cells are resistant to etoposide [Letter]. Journal of Investigative Dermatology 134(3), pp. 867-870. (10.1038/jid.2013.377)
- Colmont, C. S. et al. 2013. CD200-expressing human basal cell carcinoma cells initiate tumor growth. Proceedings of the National Academy of Sciences of the United States of America 110(4), pp. 1434-1439. (10.1073/pnas.1211655110)
- Daly, C. S. 2013. The roles of the APC proteins in homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
- Eccles, S. A. et al. 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research 15(5), pp. R92. (10.1186/bcr3493)
- Gui, L. and Homer, H. 2013. Hec1-dependent cyclin B2 stabilization regulates the G2-M transition and early prometaphase in mouse oocytes. Developmental Cell 25(1), pp. 43-54. (10.1016/j.devcel.2013.02.008)
- Hammoudi, A. et al. 2013. Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC). Biochemical and Biophysical Research Communications 440(3), pp. 364-370. (10.1016/j.bbrc.2013.08.076)
- Holik, A. et al. 2013. Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner. Stem Cells 31(11), pp. 2457-2466. (10.1002/stem.1498)
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