Cyhoeddiadau academaidd
Fel yr unig sefydliad yn Ewrop sydd wedi ei neilltuo ar gyfer ymchwilio i bôn-gelloedd cancr, mae gwaith ein ymchwilwyr yn cael ei gyhoeddi'n reolaidd.
Ar y dudalen hon, fe ddewch chi o hyd i restr o erthyglau a phapurau diweddar a fydd, gobeithio, yn ddefnyddiol i chi. Nodwch bod y cynnwys isod yn Saesneg.
2025
- Farrell, L. et al. 2025. Organoids with a type 1 collagen scaffold to model bacterial cancer therapy. Cells 14(7), article number: 524. (10.3390/cells14070524)
- Hodson, K. et al. 2025. Targeting cancer with Paris' arrow: An updated perspective on targeting Wnt Receptor Frizzled 7. Sci 7(2), article number: 61. (10.3390/sci7020061)
2024
- Badder, L. et al. 2024. The αvβ6 integrin specific virotherapy, Ad5NULL-A20.FCU1, selectively delivers 2 potent “in-tumour” chemotherapy to Pancreatic Ductal Adenocarcinoma. British Journal of Cancer 131, pp. 1694-1706. (10.1038/s41416-024-02869-3)
- de Paula do Nascimento, R. et al. 2024. Myrciaria jaboticaba fruit peel: Bioactive composition as determined by distinct harvest seasons and in vitro anti-cancer activity. Plants 13(20), article number: 2907. (10.3390/plants13202907)
- Hill, L. 2024. Unravelling the early responses to KrasG12D activation in the adult lung epithelium. PhD Thesis, Cardiff University.
- Lovatt, C. et al. 2024. Pigment epithelium derived factor drives melanocyte proliferation and migration in neurofibromatosis café au lait macules. Skin Health and Disease 4(5), article number: e394. (10.1002/ski2.394)
- Padilha, A., Jones, E., Cutting, S., Godkin, A., Gallimore, A. and Parry, L. 2024. Regulatory T cells play a role in determining the tumourigenicity of the Intestinal Stem Cell Niche. Gastro Hep Advances 4(2), article number: 100559. (10.1016/j.gastha.2024.09.014)
- Seaton, G., Smith, H., Brancale, A., Westwell, A. D. and Clarkson, R. 2024. Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age. Molecular Cancer 23(1), article number: 7. (10.1186/s12943-023-01922-8)
- Tornillo, G., Warrington, L., Kendrick, H., Higgins, A. T., Hay, T., Beck, S. and Smalley, M. J. 2024. Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model. Disease Models and Mechanisms 17(1), article number: dmm050211. (10.1242/dmm.050211)
- Vaiasicca, S. et al. 2024. Transcriptomic analysis reveals the anti-cancer effect of gestational mesenchymal stem cell secretome. Stem Cells Translational Medicine 13(7), pp. 693-710. (10.1093/stcltm/szae024)
2023
- Almotiri, A., Boyd, A. S. and Rodrigues, N. P. 2023. Zeb1 Regulates the function of lympho-myeloid primed progenitors after transplantation. Biomolecules 13(9), article number: 1386. (10.3390/biom13091386)
- Alshahrany, N., Begum, A., Siebzehnrubl, D., Jimenez-Pascual, A. and Siebzehnrubl, F. A. 2023. Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion. Cancer Letters 571, article number: 216349. (10.1016/j.canlet.2023.216349)
- Arana Echarri, A., Struszczak, L., Beresford, M., Campbell, J. P., Jones, R. H., Thompson, D. and Turner, J. E. 2023. Immune cell status, cardiorespiratory fitness and body composition among breast cancer survivors and healthy women: a cross sectional study. Frontiers in Physiology 14, article number: 1107070. (10.3389/fphys.2023.1107070)
- Bates, E. A., Lovatt, C., Plein, A. R., Davies, J. A., Siebzehnrubl, F. A. and Parker, A. L. 2023. Engineering adenoviral vectors with improved GBM selectivity. Viruses 15(5), article number: 1086. (10.3390/v15051086)
- Brown, J. et al. 2023. A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance. Biochemical Pharmacology 208, article number: 115410. (10.1016/j.bcp.2023.115410)
- Chan, Y. et al. 2023. (+)-catechin attenuates multiple atherosclerosis-associated processes in vitro, modulates disease-associated risk factors in C57BL/6J mice and reduces atherogenesis in LDL receptor deficient mice by inhibiting inflammation and increasing markers of plaque stability. Molecular Nutrition & Food Research 67(14), article number: 2200716. (10.1002/mnfr.202200716)
- Edmunds, G., Beck, S., Umakant Kale, K., Spasic, I., O'Neill, D., Brodbelt, D. and Smalley, M. J. 2023. Associations between dog breed and clinical features of mammary epithelial neoplasia in bitches: an epidemiological study of submissions to a single diagnostic pathology centre between 2008-2021. Journal of Mammary Gland Biology and Neoplasia 28(6) (10.1007/s10911-023-09531-3)
- Jones, R. et al. 2023. A Phase I/II trial of Oral SRA737 (a Chk1 Inhibitor) given in combination with low-dose gemcitabine in patients with advanced cancer. Clinical Cancer Research 29(2), pp. 331-340. (10.1158/1078-0432.CCR-22-2074)
- Kristeleit, R. et al. 2023. A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer. British Journal of Cancer (10.1038/s41416-023-02279-x)
- Michael, D. R., Kerry-Smith, J., Webberley, T. S., Murphy, K., Plummer, S. F., Parry, L. and Marchesi, J. R. 2023. Does flow culture impact upon gut-probiotic interactions: a comparison with static culture. Journal of Functional Foods 104, article number: 105519. (10.1016/j.jff.2023.105519)
- Moore, J. W., Dale, T. C. and Woolley, T. E. 2023. Modelling polarity-driven laminar patterns in bilayer tissues with mixed signalling mechanisms. SIAM Journal on Applied Dynamical Systems 22(4), pp. 2945-2990. (10.1137/22M1522565)
- Ordonez, L., Tornillo, G., Kendrick, H., Hay, T. and Smalley, M. J. 2023. NOTCH and AKT signalling interact to drive mammary tumour heterogeneity. Cancers 15(17), article number: 4324. (10.3390/cancers15174324)
- Rastogi, N. et al. 2023. Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia 37, pp. 276-287. (10.1038/s41375-022-01801-z)
- Sanz-Castillo, B. et al. 2023. The MASTL/PP2A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner. The EMBO Journal 42(2), article number: e110833. (10.15252/embj.2022110833)
- Shorning, B., Trent, N., Griffiths, D. F., Worzfeld, T., Offermanns, S., Smalley, M. J. and Williamson, M. 2023. Plexin-B1 mutation drives metastasis in prostate cancer mouse models. Cancer Research Communications 3(3), pp. 444-458. (10.1158/2767-9764.CRC-22-0480)
- Singh, N., Siebzehnrubl, F. A. and Martinez Garay, I. 2023. Transcriptional control of embryonic and adult neural progenitor activity. Frontiers in Neuroscience 17, article number: 1217596. (10.3389/fnins.2023.1217596)
- Varney, D. et al. 2023. Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016. Veterinary Record 193(5), article number: e3054. (10.1002/vetr.3054)
2022
- Almotiri, A., Abdelfattah, A. and Rodrigues, N. P. 2022. Flow cytometry analysis of hematopoietic stem/progenitor cells and mature blood cell subsets in atherosclerosis. In: Ramji, D. ed. Atherosclerosis., Vol. 2419. Methods in Molecular Biology Springer, pp. 583-595., (10.1007/978-1-0716-1924-7_36)
- Anjos-Afonso, F. et al. 2022. Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population. Nature Communications 13, article number: 2048. (10.1038/s41467-022-29675-w)
- Banerjee, S. et al. 2022. A phase I trial of CT900, a novel α-folate receptor-mediated thymidylate synthase inhibitor, with expansion cohorts in patients with high grade serous ovarian cancer. Clinical Cancer Research 22, article number: 1268. (10.1158/1078-0432.CCR-22-1268)
- Bates, E. A. et al. 2022. Development of a low seroprevalence, αvβ6 integrin selective virotherapy based on human adenovirus type 10. Molecular Therapy - Oncolytics 25, pp. 43-56. (10.1016/j.omto.2022.03.007)
- D'Ambrogio, J., Hill, L. and Hogan, C. 2022. Cell competition: Clonal competition protects against early tumorigenesis. Current Biology 32(1), pp. PR52-R54. (10.1016/j.cub.2021.11.029)
- Dimitriou, P., Li, J., Tornillo, G., Smalley, M. and Barrow, D. 2022. Droplet incubator: a new droplet-based model to investigate living cell-synthetic cell interactions. Presented at: MicroTAS 2022, Hangzhou, China, 23-27 October 2022.
- Engel, R. M. et al. 2022. Modeling colorectal cancer: A bio-resource of 50 patient-derived organoid lines. Journal of Gastroenterology and Hepatology 37(5), pp. 898-907. (10.1111/jgh.15818)
- Hidalgo, M. et al. 2022. A preclinical and phase Ib study of palbociclib plus nab-paclitaxel in patients with metastatic adenocarcinoma of the pancreas. Cancer Research Communications 2(11), pp. 1326–1333. (10.1158/2767-9764.CRC-22-0072)
- Howell, S. J. et al. 2022. Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial. The Lancet Oncology 23(7), pp. 851-864. (10.1016/s1470-2045(22)00284-4)
- Koushyar, S., Meniel, V. S., Phesse, T. J. and Pearson, H. B. 2022. Exploring the Wnt pathway as a therapeutic target for prostate cancer. Biomolecules 12(2), article number: 309. (10.3390/biom12020309)
- May, S. et al. 2022. Modification of diet to reduce the stemness and tumourigenicity of murine and human intestinal cells. Molecular Nutrition & Food Research 66(19), article number: 2200234. (10.1002/mnfr.202200234)
- Menendez-Gonzalez, J. B., Strange, K. E., Bassetto, M., Brancale, A., Rodrigues, N. P. and Ferla, S. 2022. Ligand-based discovery of a novel GATA2 inhibitor targeting acute myeloid leukemia cells. Frontiers In Drug Discovery 2, article number: 1013229. (10.3389/fddsv.2022.1013229)
- Menendez-Gonzalez, J. B. and Rodrigues, N. P. 2022. Exploring the associations between clonal hematopoiesis of indeterminate potential, myeloid malignancy, and atherosclerosis. In: Ramji, D. ed. Atherosclerosis., Vol. 2419. Methods in Molecular Biology Springer, pp. 73-88., (10.1007/978-1-0716-1924-7_5)
- Moore, J. W., Dale, T. C. and Woolley, T. E. 2022. Polarity driven laminar pattern formation by lateral-inhibition in 2D and 3D bilayer geometries. IMA Journal of Applied Mathematics 87(4), pp. 568-606.
- Morgan, H. J. et al. 2022. CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis. Journal of Clinical Investigation 132(21), article number: e150750. (10.1172/JCI150750)
- Owen, J. S., Clayton, A. and Pearson, H. B. 2022. Cancer-associated fibroblast heterogeneity, activation and function: implications for prostate cancer. Biomolecules 13(1), article number: 67. (10.3390/biom13010067)
- Parry, L. 2022. Stemming the flow toward disease: A research profile of Lee Parry. eFood 3(6), article number: e46. (10.1002/efd2.46)
- Petrik, D., Jorgensen, S., Eftychidis, V. and Siebzehnrubl, F. A. 2022. Singular adult neural stem cells do not exist. Cells 11(4), article number: 722. (10.3390/cells11040722)
- Routledge, D. et al. 2022. The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer. eLife 11, article number: e77376. (10.7554/elife.77376)
- Saad, F. et al. 2022. Patient-reported outcomes with olaparib plus abiraterone versus placebo plus abiraterone for metastatic castration-resistant prostate cancer: a randomised, double-blind, phase 2 trial. The Lancet Oncology 23(10), pp. 1297-1307. (10.1016/S1470-2045(22)00498-3)
- Siebzehnrubl, F. A. 2022. Isolating and culturing of precursor cells from the adult human brain. In: Deleyrolle, L. P. ed. Neural Progenitor Cells: Methods and Protocols., Vol. 2389. Methods in Molecular Biology New York, NY: Springer, pp. 95-102., (10.1007/978-1-0716-1783-0_9)
- Williams, N. G. and Parry, L. 2022. Balancing the scales: Do healthy lifestyle choices offset the colorectal cancer risk of unhealthy choices?. eFood 3(6), article number: e45. (10.1002/efd2.45)
- Woolley, T., Hill, W. and Hogan, C. 2022. Accounting for dimensional differences in stochastic domain invasion with applications to precancerous cell removal. Journal of Theoretical Biology 541, article number: 111024. (10.1016/j.jtbi.2022.111024)
2021
- Abdelfattah, A. M. et al. 2021. Gata2 haploinsufficiency promotes proliferation and functional decline of HSCs with myeloid bias during aging. Blood Advances 5(20), pp. 4285-4290. (10.1182/bloodadvances.2021004726)
- Almotiri, A. et al. 2021. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. Journal of Clinical Investigation 131(1), article number: e129115. (10.1172/JCI129115)
- Arana Echarri, A. et al. 2021. A phenomic perspective on factors influencing breast cancer treatment: integrating aging and lifestyle in blood and tissue biomarker profiling. Frontiers in Immunology 11, article number: 616188. (10.3389/fimmu.2020.616188)
- Castro, J. et al. 2021. A nuclear-directed ribonuclease variant targets cancer stem cells and inhibits migration and invasion of breast cancer cells. Cancers 13(17), article number: 4350. (10.3390/cancers13174350)
- Davies, J. A. et al. 2021. Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20. Viruses 13(5), article number: 864. (10.3390/v13050864)
- Dimitriou, P., Li, J., Tornillo, G., McCloy, T. and Barrow, D. 2021. Droplet microfluidics for tumor drug-related studies and programmable artificial cells. Global Challenges 5(7), article number: 2000123. (10.1002/gch2.202000123)
- Edmunds, G. L. et al. 2021. Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine Medicine and Genetics 8, article number: 2. (10.1186/s40575-021-00100-7)
- Gupta, B. et al. 2021. The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus. Cell Reports 36(8), article number: 109588. (10.1016/j.celrep.2021.109588)
- Hill, W. et al. 2021. EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neigbors in the adult pancreas. Current Biology 31(12), pp. 2550-2560., article number: E5. (10.1016/j.cub.2021.03.094)
- Jukes, Z. et al. 2021. Lipid profiling of mouse intestinal organoids for studying APC mutations. Bioscience Reports 41(3), article number: BSR20202915. (10.1042/BSR20202915)
- Kermanizadeh, A., Jacobsen, N. R., Murphy, F., Parry, L., Zhang, H. and Møller, P. 2021. A review of the current state of nanomedicines for targeting and treatment of cancers - achievements and future challenges. Advanced Therapeutics 4(2), article number: 2000186. (10.1002/adtp.202000186)
- Lawson, H. et al. 2021. JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells. Blood Advances 5(3), pp. 889-899. (10.1182/bloodadvances.2020002702)
- Lawson, H. et al. 2021. CITED2 coordinates key haematopoietic regulatory pathways to maintain the HSC pool in both steady-state haematopoiesis and transplantation. Stem Cell Reports 16(11), pp. 2784-2797. (10.1016/j.stemcr.2021.10.001)
- Mian, S. A., Dos Anjos-Afonso, F. and Bonnet, D. 2021. Advances in human immune system mouse models for studying human hematopoiesis and cancer immunotherapy. Frontiers in Immunology 11, article number: 619236. (10.3389/fimmu.2020.619236)
- Moore, J. W., Lau, Z., Kaouri, K., Dale, T. C. and Woolley, T. E. 2021. A general computational framework for COVID-19 modelling with applications to testing varied interventions in education environments. COVID 1(4), pp. 674-703. (10.3390/covid1040055)
- Moss, J. W. E. et al. 2021. Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. Food and Function 12(8), pp. 3657-3671. (10.1039/D0FO02867C)
- O'Morain, V. L. et al. 2021. The Lab4P consortium of probiotics attenuates atherosclerosis in LDL receptor deficient mice fed a high fat diet and causes plaque stabilization by inhibiting inflammation and several pro-atherogenic processes. Molecular Nutrition & Food Research 65(17), article number: 2100214. (10.1002/mnfr.202100214)
- Ordonez, L. D. et al. 2021. Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model. Disease Models and Mechanisms 14(5), article number: dmm048736. (10.1242/dmm.048736)
- Pope, I. et al. 2021. Identifying subpopulations in multicellular systems by quantitative chemical imaging using label-free hyperspectral CARS microscopy. Analyst 146(7), pp. 2277-2291. (10.1039/D0AN02381G)
- Rastogi, N. et al. 2021. Use of an anti-CD200 blocking antibody improves immune responses to AML in vitro and in vivo. British Journal of Haematology 193(1), pp. 155-159. (10.1111/bjh.17125)
- Seligmann, J. F. et al. 2021. Inhibition of WEE1 is effective in TP53- and RAS-mutant metastatic colorectal cancer: a randomized trial (FOCUS4-C) comparing adavosertib (AZD1775) with active monitoring. Journal of Clinical Oncology 39(33), pp. 3705-3715. (10.1200/JCO.21.01435)
- Soukupova, J. et al. 2021. The discovery of a novel anti-metastatic Bcl3 inhibitor. Molecular Cancer Therapeutics 10(5), pp. 775-786. (10.1158/1535-7163.MCT-20-0283)
- Stott, K. J., Phillips, B., Parry, L. and May, S. 2021. Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer. Bioscience Reports 41(7), article number: BSR20204113. (10.1042/BSR20204113)
- Tran, B. M., Flanagan, D. J., Phesse, T. J., Vincan, E. and Phesse, T. 2021. Frizzled7 activates β-catenin-dependent and β-catenin-independent Wnt signalling pathways during developmental morphogenesis: implications for therapeutic targeting in colorectal cancer. In: Handbook of Experimental Pharmacology.
2020
- Adams-Smith, R., Colmont, C., Mukhtar, A., Morgan, H. and Patel, G. K. 2020. A novel oncostatin M/interleukin-31 receptor mutation in familial primary localized cutaneous amyloidosis. Clinical and Experimental Dermatology 45(2), pp. 254-256. (10.1111/ced.14059)
- Alanazi, B. et al. 2020. Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. Leukemia 34(2), pp. 427-440. (10.1038/s41375-019-0596-4)
- Badder, L. M. et al. 2020. 3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors. PLoS ONE 15(8), article number: e0235319. (10.1371/journal.pone.0235319)
- Badr, C. E., Silver, D. J., Siebzehnrubl, F. A. and Deleyrolle, L. P. 2020. Metabolic heterogeneity and adaptability in brain tumors. Cellular and Molecular Life Sciences 77, pp. 5101-5119. (10.1007/s00018-020-03569-w)
- Caye, A. et al. 2020. Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment. Leukemia 34, pp. 1658-1668. (10.1038/s41375-019-0662-y)
- Hong, D. S. et al. 2020. Tisotumab vedotin in previously treated recurrent or metastatic cervical cancer. Clinical Cancer Research 26(6), pp. 1220-1228. (10.1158/1078-0432.CCR-19-2962)
- Jardé, T. et al. 2020. Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium. Cell Stem Cell 27(4), pp. 646-662.E7., article number: VOLUME 27, ISSUE 4, P646-662.E7, OCTOBER 01, 2020. (10.1016/j.stem.2020.06.021)
- Jimenez-Pascual, A., Mitchell, K., Siebzehnrubl, F. A. and Lathia, J. D. 2020. FGF2: a novel druggable target for glioblastoma?. Expert Opinion on Therapeutic Targets 24(4), pp. 311-318. (10.1080/14728222.2020.1736558)
- Jones, R. H. et al. 2020. Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial. Lancet Oncology 21(3), pp. 345-347. (10.1016/S1470-2045(19)30817-4)
- Kiraga, L. et al. 2020. Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice. International Journal of Molecular Sciences 21(14), article number: 4991. (10.3390/ijms21144991)
- Koushyar, S., Powell, A. G., Vincan, E. and Phesse, T. J. 2020. Targeting Wnt signaling for the treatment of gastric cancer. International Journal of Molecular Sciences 21(11), article number: 3927. (10.3390/ijms21113927)
- May, S., McDermott, G., Marchesi, J. and Parry, L. 2020. Impact of black raspberries on the normal and malignant Apc deficient murine gut microbiome. Journal of Berry Research 10(1), pp. 61-76. (10.3233/JBR-180372)
- May, S., Parry, C. and Parry, L. 2020. Berry chemoprevention: do berries decrease the window of opportunity for tumourigenesis. Food Frontiers 1(3) (10.1002/fft2.32)
- Morgan, H. J. et al. 2020. Human basal cell carcinoma: the induction of anagen hair follicle differentiation. Clinical and Experimental Dermatology 45(3), pp. 309-317. (10.1111/ced.14108)
- Peltola, K. J. et al. 2020. ODM-204, a novel dual Inhibitor of CYP17A1 and androgen receptor: early results from phase I dose escalation in men with castration-resistant prostate cancer. European Urology Focus 6(1), pp. 63-70. (10.1016/j.euf.2018.08.022)
- Pires, A. et al. 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8(12), pp. 1520 - 1531. (10.1158/2326-6066.CIR-20-0070)
- Queiroz, C. J. et al. 2020. NAP1L1: a novel human colorectal cancer biomarker derived from animal models of Apc inactivation. Frontiers in Oncology 10, article number: 1565. (10.3389/fonc.2020.01565)
- Regan, J. L. and Smalley, M. J. 2020. Integrating single-cell RNA-sequencing and functional assays to decipher mammary cell states and lineage hierarchies. NPJ Breast Cancer 6, article number: 32. (10.1038/s41523-020-00175-8)
- Robinson, A. J. et al. 2020. Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3. Cancer Research 80(5), pp. 937-949. (10.1158/0008-5472.CAN-19-1920)
- Salvador, B. et al. 2020. CDK4/6 inhibitors impair recovery from cytotoxic chemotherapy in pancreatic adenocarcinoma. Cancer Cell 37(3), pp. 340-353. (10.1016/j.ccell.2020.01.007)
- Scholz, N., Kurian, K. M., Siebzehnrubl, F. A. and Licchesi, J. D. F. 2020. Targeting the ubiquitin system in glioblastoma. Frontiers in Oncology 10, article number: 574011. (10.3389/fonc.2020.574011)
- Shorning, B. Y., Dass, M. S., Smalley, M. J. and Pearson, H. B. 2020. The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT signaling. International Journal of Molecular Sciences 21(12), article number: 4507. (10.3390/ijms21124507)
- Tran, B. M. et al. 2020. The hepatitis B virus pre-core protein p22 activates Wnt sgnaling. Cancers 12(6), article number: 1435. (10.3390/cancers12061435)
- Turnham, D. J., Bullock, N., Dass, M. S., Staffurth, J. N. and Pearson, H. B. 2020. The PTEN conundrum: how to target PTEN-deficient prostate cancer. Cells 9(11), article number: 2342. (10.3390/cells9112342)
- Turnham, D. J., Yang, W. W., Davies, J., Varnava, A., Ridley, A. J., Conlan, R. S. and Clarkson, R. W. E. 2020. Bcl-3 promotes multi-modal tumour cell migration via NF-kB1 mediated regulation of Cdc42. Carcinogenesis 41(10), pp. 1432-1443. (10.1093/carcin/bgaa005)
- Valle-Encinas, E. and Dale, T. C. 2020. Wnt ligand and receptor patterning in the liver. Current Opinion in Cell Biology 62, pp. 17-25. (10.1016/j.ceb.2019.07.014)
2019
- de Bono, J. S. et al. 2019. Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial. Lancet Oncology 20(3), pp. 383-393. (10.1016/S1470-2045(18)30859-3)
- Eissman, M. F. et al. 2019. IL-33 mediated mast cell activation promotes gastric cancer through macrophage mobilization. Nature Communications 10, article number: 2735. (10.1038/s41467-019-10676-1)
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- Flanagan, D. J., Vincan, E. and Phesse, T. J. 2019. Wnt signaling in cancer: not a binary ON:OFF switch. Cancer Research (10.1158/0008-5472.CAN-19-1362)
- French, R. and Tornillo, G. 2019. Heterogeneity of mammary stem cells. Advances in Experimental Medicine and Biology 1169, pp. 119-140. (10.1007/978-3-030-24108-7_7)
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2018
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2017
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2016
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2015
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2013
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2012
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2011
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2010
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2009
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2008
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2007
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