The Intestinal Cancer Research Group models colorectal cancer in the mouse and assesses pathway synergies and antagonisms in-vivo and validating therapeutic targets.
Led by Deputy Director, Dr Matt Smalley, this research group is trying to understand why tumours which originate in a single tissue can have very different appearances, biology and behaviour.
The Targeting Metastasis group focuses on identifying novel therapeutic strategies to eliminate or modify the cancer cells responsible for the spread of tumours around the body.
Led by Dr Joaquin de Navascués, this research group focuses on understanding the molecular mechanisms whereby tissue stem cells balance differentiation and self-renewal.
The Cancer and Cell Signalling research group investigates the requirement of cell signalling during homeostasis, to identify novel therapeutic targets and strategies for the treatment of cancer.
