Ewch i’r prif gynnwys

Cardiff University Nanosome Network

Measuring Extracellular Vesicles, Liposomes and other nanoparticles and their interactions with cells and biological fluids.

This new University-funded research network aims to support greater interaction between researchers across disciplines in the challenging research area of nanometre sized colloidal agents and their measurement and manipulation in medicine.

By this we mean:

  • extracellular vesicles (exosomes and microvesicles)
  • liposomes
  • synthetic nanoparticles (such as polymer-gold conjugates, quantum dots, and many others).

There is enormous global interest in the application of such colloids in medicine, as a modality to deliver drugs/macromolecules in a better-targeted fashion. There is also major expansion in the use of natural, cell-derived vesicles as drug delivery systems or as disease biomarkers.

Studying nano-particulates and their application in disease model systems is very challenging. This is because these entities are so small, and because the way particles interact in biological systems is complex.

This topic area therefore requires the pooling of infrastructural resources, as well as varied scientific approaches and expertise, in order to bring about greater understanding and enhance Cardiff University and UK capabilities in this area.

Our mission is to build upon established knowledge in manufacture of nano-particulates, nano-measurement and nano-sorting devices, cell, tissue and whole body model systems, and to bring together this collective expertise across seven Schools through a series of networking events.

In addition to workshops, involving external internationally renowned  experts, and focussed sandpit discussions, the network will drive new, creative thinking through short lab-exchange visits. This will provide early career researchers with first hand experience of a range of nano-related methods and devices, with the aim of escalating our activities in this topic area.

Amcanion

The Nanosome network has a broad remit, with the overarching goal of increasing research activities and research publication outputs relating to nanoparticles. We aim to:

  • foster greater inter-School communication and collaboration relating to the manufacture, measurement and application of nanoparticles
  • identify basic technical, clinical and ethical challenges and unmet needs through our network
  • apply existing tools to the challenge of nanoscale measurement or nano-sorting, and examine their utility in  medically relevant applications (eg biomarkers)
  • develop new protocols or devices for improved reproducibility in nano-particle production, and systems to quality assure this
  • apply nanoparticles in varied formations to biological model systems, including single cell, tissue and whole body distribution studies.

Our goal is to be inclusive and expand the network, including by bringing in early career researchers, throughout the two-year funding period. We also aim to seek further funding in this area.

Get in touch

To find out more about our work and how you can get involved, please contact our Network leaders:

Staff academaidd

Yr Athro Aled Clayton

Yr Athro Aled Clayton

Senior Lecturer

Email
claytona@caerdydd.ac.uk
Telephone
+44 (0)29 2251 0589
Yr Athro Rachel Errington

Yr Athro Rachel Errington

Professor

Email
erringtonrj@caerdydd.ac.uk
Telephone
+44 (0)29 2068 7301
Dr Jason Webber

Dr Jason Webber

Research Fellow

Email
webberjp@caerdydd.ac.uk
Telephone
+44 (0)29 2068 7306
Dr Zsuzsanna Tabi

Dr Zsuzsanna Tabi

Senior Lecturer

Email
tabiz@caerdydd.ac.uk
Telephone
+44 (0)29 2251 0550
Yr Athro Donald Fraser

Yr Athro Donald Fraser

Clinical Reader

Email
fraserdj@caerdydd.ac.uk
Telephone
+44 (0)29 2074 8449
Dr Robert Steadman

Dr Robert Steadman

Senior Lecturer

Email
steadmanr@caerdydd.ac.uk
Telephone
+44 (0)29 2074 8390
Dr Timothy Bowen

Dr Timothy Bowen

Senior Lecturer

Email
bowent@caerdydd.ac.uk
Telephone
+44 (0)29207 48389
Dr Dafydd Alwyn Dart

Dr Dafydd Alwyn Dart

Senior Research Fellow

Email
dartd@caerdydd.ac.uk
Telephone
+44 (0)29 2068 7069
Yr Athro Christopher Marshall

Yr Athro Christopher Marshall

Cyfarwyddwr Canolfan Delweddu Tomograffeg Gollwng Positronau (PET) at ddibenion Ymchwil a Diagnostig

Email
marshallc3@caerdydd.ac.uk
Telephone
+44 (0)29 2074 8164
Dr Stephen Paisey

Dr Stephen Paisey

Research Fellow

Email
paiseysj@caerdydd.ac.uk
Telephone
+44 (0)29 2074 3676
Yr Athro Yves Barde

Yr Athro Yves Barde

Professor / Sêr Cymru Research Chair in Neurobiology

Email
bardey@caerdydd.ac.uk
Telephone
+44 (0)29 2087 0987
Yr Athro Paola Borri

Yr Athro Paola Borri

Professor

Email
borrip@caerdydd.ac.uk
Telephone
+44 (0)29 2087 9356
Dr Peter Watson

Dr Peter Watson

Director for Postgraduate Education, Reader, Academic lead of imaging facilities, Postgraduate Research Teaching Co-ordinator

Email
watsonpd@caerdydd.ac.uk
Telephone
+44 (0)29 2087 9042
Yr Athro Arwyn Tomos Jones

Yr Athro Arwyn Tomos Jones

Professor of Membrane Traffic and Drug Delivery

Siarad Cymraeg
Email
jonesat@caerdydd.ac.uk
Telephone
+44 (0)29 2087 6431
Yr Athro James Birchall

Yr Athro James Birchall

Professor of Pharmaceutical Sciences

Email
birchalljc@caerdydd.ac.uk
Telephone
+44 (0)29 2087 5815
Dr Julie Albon

Dr Julie Albon

Lecturer, Optic Nerve Head Group Leader, Person designate, Cathays Park HTA satellite licence

Email
albonj@caerdydd.ac.uk
Telephone
+44 29208 75427
Yr Athro Keith Meek

Yr Athro Keith Meek

Head of Biophysics Research Group, Senior Mentor

Email
meekkm@caerdydd.ac.uk
Telephone
+44 (0)29 2087 6317
Dr Philip Lewis

Dr Philip Lewis

Research Associate & Electron Microscopy Specialist

Email
lewispn@caerdydd.ac.uk
Telephone
+44 (0)29 208 70459
Yr Athro Phil Stephens

Yr Athro Phil Stephens

Deon Rhyngwladol ac Ymgysylltu y Coleg, Athro Bioleg Celloedd

Email
stephensp@caerdydd.ac.uk
Telephone
+44 (0)29 2074 2529
Yr Athro Rachel Waddington

Yr Athro Rachel Waddington

Cyfarwyddwr Cyswllt Ymgysylltu a Menter, Professor in Oral Biochemistry, Director of Postgraduate Research Studies

Email
waddingtonrj@caerdydd.ac.uk
Telephone
+44 (0)29 225 10647
Dr Sharon Dewitt

Dr Sharon Dewitt

Darlithydd

Email
dewitt@caerdydd.ac.uk
Telephone
+44 (0)29 2251 0665
Dr Wayne Nishio Ayre

Dr Wayne Nishio Ayre

Darlithydd mewn Bioddeunyddiau

Email
ayrewn@caerdydd.ac.uk
Telephone
+44(0) 292 2510 660
Dr Alison Paul

Dr Alison Paul

Senior Lecturer in Physical Chemistry

Email
paula3@caerdydd.ac.uk
Telephone
+44 (0)29 2087 0419
Yr Athro Sam Evans

Yr Athro Sam Evans

Pennaeth Ysgol

Email
evanssl6@caerdydd.ac.uk
Telephone
+44 (0)29 2087 6876
David Barrow

David Barrow

Professor

Email
barrow@caerdydd.ac.uk
Telephone
+44 (0)29 2087 5921
Yr Athro Adrian Porch

Yr Athro Adrian Porch

Professor

Email
porcha@caerdydd.ac.uk
Telephone
+44 (0)29 2087 5954
Dr Xin Yang (Chris)

Dr Xin Yang (Chris)

Lecturer - Teaching and Research

Email
yangx26@caerdydd.ac.uk
Telephone
+44 (0)29 2087 5708

The network will organise a series of diverse events. Participants across all schools will interact as a community and as smaller groups to help us explore novel collaborative opportunities and to develop these new ideas towards research papers and funding bids.

Network events are currently being planned and will be advertised here. A theme-setting sandpit is intended for spring, and a large formal workshop gathering with external guests planned before the summer break.