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Targeting Antibiotic-Resistant Bacteria

13 July 2011

A new technique which targets antibiotic-resistant bacteria and shields patients from the toxic aspects of the antibiotic drug has been developed by University scientists. Dr Elaine Ferguson explained how colleagues in the Schools of Dentistry, Chemistry and Medicine have collaborated to develop a technique that minimises the toxicity of the antibiotic drug by shielding it with a nano-sized biodegradable polymer that is degraded at a site of infection.

"Our new approach allows existing effective therapies to be improved to help patients with severe infections who may otherwise suffer significant side effects after treatment” she added.

Dr Peter Griffiths added that “characterisation of the nanoscale structure of such conjugates by small-angle neutron scattering is essential in defining the structure-property relationships” of these exciting new drug delivery systems.

The research was supported by The Severnside Alliance for Translational Research (SARTRE) - a major collaboration between Cardiff and Bristol Universities designed to translate medical research to improve lives.

http://www.cf.ac.uk/news/articles/targeting-antibiotic-resistant-bacteria-7007.html