Dr Joel Loveridge
Telephone:+44 (0)29 208 74029
Fax:+44 (0)29 208 74030
Research Group: Chemical Biology
I am interested in the relationship between the structure, dynamics and function of enzymes, as a route to understanding and controlling nature’s chemistry. My work places particular emphasis on how binding partners (small molecules, nucleic acids, or other proteins) affect a protein’s dynamics and how the protein affects its binding partners. Current projects involve dihydrofolate reductase, phototropin domains, and amyloid peptides. This work involves multidimensional NMR spectroscopy, using Cardiff’s flagship 600 MHz Bruker NMR spectrometer equipped with a quadruple resonance QCI cryoprobe, in conjunction with other biophysical techniques. I also have an interest in antibiotic biosynthesis.
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CH0003 - Chemistry of Organic Compounds