Infection and immunity

We conduct high quality basic and translational research that is internationally recognised, widely referenced and globally exploited for the benefit of human health.

Our research is grouped into four themes, each led by an integrated team of non-clinical and clinical academic staff who deliver fundamental and applied research of translational relevance. Many of our clinical research leads have joint NHS appointments combined with protected research time.

We deliver a large component of teaching within undergraduate medical and pharmacology teaching programmes in the form of lectures, practicals, tutorials and demonstrations, with an emphasis on small group teaching within years 2 - 4. We are also involved in postgraduate teaching, teaching administration, assessment and curriculum development.

The majority of our research is conducted through the Systems Immunity Research Institute.

Aims

  • To understand the underlying biology of infectious diseases.
  • To understand immune system function and dysfunction during health and disease.
  • To exploit this understanding to develop novel therapeutic and diagnostic approaches.
  • To disseminate this knowledge to the public, patients, professionals and students.

Themes

Infection

Infection

Members have a broad portfolio of research interests with particular strengths in virology, viral immunology, antimicrobial resistance and diagnosis of fungal infection.

Inflammation

Inflammation

Inflammation represents the coordinated immune response to infection, trauma and injury. When appropriately controlled, inflammation ensures competent host defence and prevents excessive damage of the affected tissue or organ structure.

Immunology

Immunology

Immunology Research focuses in several areas. We are especially strong in conventional and unconventional T-cell immunity, cancer immunotherapy, autoimmune disease, homing and trafficking of immune cells and the structure biology of antigen receptors and the ligands they recognise.