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Studies and trials

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A randomised controlled trial of contrast enhanced colonoscopy in the reduction of right sided bowel cancer.


Development of a core outcome set for interventions to enhance proxy decisions about research on behalf of adults who lack capacity to consent.


The COPELIA trial is testing whether two new tablet medications delay progression of endometrial cancer more than chemotherapy alone.


This trial looked at whether it was useful for people with cancer of the back passage (rectal cancer) to have chemotherapy before surgery.


CORINTH is a trial for patients with advanced (stage 3 and 4) anal cancer.


CREAM was a double blind, randomised controlled trial to assess whether children with eczema benefitted from antibiotic treatment and was based in general practices and dermatology clinics in Wales, Scotland, and the West of England.


Family members’ experiences of informed consent and proxy decision making for research involving adults lacking capacity.

Developing clinical applications for a novel multi-task functional assessment

The Clinch Token Transfer Test (C3T) is a novel multi-task functional assessment that has great potential as a sensitive end point for use in clinical trials in neurodegeneration and neurodysfunction.


Development of an intervention to Optimise use of Pre-Exposure Prophylaxis (PrEP) to prevent HIV-acquisition in at-risk individuals living in Wales (DO-PrEP).


The DOMINO-HD study (Multi-Domain Lifestyle Targets for Improving ProgNOsis) is exploring how digital technologies, such as wearable fitness trackers, can be used to support people with Huntington’s disease (HD).