A Phase I/II single-arm trial to evaluate the combination of cisplatin and gemcitabine with the mTOR inhibitor temsirolimus for treatment of advanced cancers, including first-line treatment of patients with advanced transitional cell carcinoma of the urothelium.
A randomised phase II trial of carboplatin and gemcitabine +/- vandetanib in first line Treatment Of advanced Urothelial cell Cancer in patients who are not suitable to receive cisplatin.
A research study to determine low vision practitioners’ current practice and beliefs around depression, and to evaluate the impact of training on attitudes and practice.
A randomised controlled feasibility study of TRAK musculoskeletal digital self-management physiotherapy intervention for individuals with musculoskeletal pain.
The TRON study is a randomised, double blind, placebo-controlled study of RAD001 (Everolimus) in the treatment of neurocognitive problems in tuberous sclerosis.
A randomised, double-blind, placebo controlled, parallel group, multi-centre trial in adult subjects with newly diagnosed type 1 diabetes mellitus investigating the effect of Verapamil SR on preservation of beta-cell function.