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Dr Karen Reed 

Position:Research Associate

Telephone:+44(0)29 20688497
Fax:+44 (0)29 208 74116
Location:European Cancer Stem Cell Research Institute, Cardiff School of Biosciences Hadyn Ellis Building, Maindy Road, Cardiff CF24 4HQ

Research Overview

My main lines of research are:

    • To exploit the use of transgenic mouse models to determine the critical molecular events which contribute to the initiation and progression of tumourigenesis (primarily within the intestine and liver).
    • To investigate the importance of the genes Cbx3 and HMGB1 in intestinal homeostasis and tumourigenesis
    • To determine the epigenetic consequences of altered gestational diet, and ascertain the significance of these on lifetime tumour risk.
    • To investigate the alternative roles of APC (Adenomatous polyposis coli) which contribute to tumourigenesis but are independent to APC’s role regulating Wnt signalling.