Dr Karen Reed
Position:Research Associate
Email:ReedKR@cardiff.ac.uk
Telephone:+44 (0)29 208 75153
Fax:+44 (0)29 208 74116
Extension:75153
Location:Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Telephone:+44 (0)29 208 75153
Fax:+44 (0)29 208 74116
Extension:75153
Location:Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Research Overview
My main lines of research are:
- To exploit the use of transgenic mouse models to determine the critical molecular events which contribute to the initiation and progression of tumourigenesis (primarily within the intestine and liver).
- To investigate the importance of the genes Cbx3 and HMGB1 in intestinal homeostasis and tumourigenesis
- To determine the epigenetic consequences of altered gestational diet, and ascertain the significance of these on lifetime tumour risk.
- To investigate the alternative roles of APC (Adenomatous polyposis coli) which contribute to tumourigenesis but are independent to APC’s role regulating Wnt signalling.