Prof Jim Murray
Telephone:+44 (0)29 208 76676
Fax:+44 (0)29 208 74117
Location:Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Confocal microscopy allows us to analyse the expression of cell division genes in specific cell types, as in the example of this root tip, where gene expression is visualised with green fluorescent protein.
The group has two major research interests in plant cellular development and molecular biotechnology.
Plant cellular development seeks to understand how processes operating at the level of the cell are integrated with plant development. Plants grow continuously and are responsive to the environment, so cell division and cellular differentiation are closely integrated in growth processes. We focus in particular on understanding how cell division is controlled in plants, how it responds to the environment, and how it is co-ordinated with differentiation to build complex and highly organised structures. We study cell division both during development and in cell cultures applying a range of genetic, cell biological, imaging, transgenic and systems biology approaches in a range of developmental situations.
Molecular biotechnology is the study and application of molecular approaches to practical problems. The lab has a longstanding interest in two areas- the molecular and cellular mechanisms by which plasmids are maintained in yeast, and the applications of bioluminescence to diagnostic systems, in particular a new technology known as BART (Bioluminescent Assay in Real-Time) which can detect nucleic acid amplification as it takes place in portable devices.