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Dr Nicholas A. Kent  -  DPhil

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Link to ScopusTM Database

Selected Publications

Maruyama H., Harwood J.C., Moore K.M. Paszkiewicz K., Durley S.C., Fukushima H., Atomi H., Takeyasu K., Kent N.A. (2013) An alternative beads-on-a-string chromatin architecture in Thermococcus kodakarensis. EMBO Rep. 14:711-717.

Platt J.L., Kent N.A., Harwood A.J., Kimmel A.R. (2013) Analysis of chromatin organization by deep sequencing technologies. Methods Mol. Biol. 983:173-183.

Chambers A.L., Ormerod G., Durley S.C., Sing T.L., Brown G.W., Kent N.A., Downs J.A.(2012b) The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Genes Dev. 26:2590-2603.

Durand-Dubief M., Will W.R, Petrini E., Theodorou D., Harris R.R., Crawford M.R., Paszkiewicz K., Krueger F., Correra R.M., Vetter A.T., Miller J.R., Kent N.A., Varga-Weisz P. (2012) SWI/SNF-Like Chromatin Remodeling Factor Fun30 Supports Point Centromere Function in S. cerevisiae. PLoS Genet. 8:e1002974.

Chambers A.L., Brownlee P.M., Durley S.C., Beacham T., Kent N.A., Downs J.A. (2012a) The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses. PLoS One 7:e32016.

Kent N.A., Adams S., Moorhouse, A. & Paszkiewicz, K. (2011) Chromatin particle spectrum analysis: a method for comparative chromatin structure analysis using paired-end mode next-generation DNA sequencing. Nucleic Acids Res. 39:e26.

Loney E.R., Inglis P.W., Sharp S., Pryde F.E., Kent N.A., Mellor J., Louis E.J. (2009) Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae. Epigenet. Chrom. 2:18.

Kent N.A., Chambers, A.L. & Downs, J.A.(2007) Dual chromatin remodelling roles for RSC during DNA double-strand break induction and repair at the yeast MAT locus. J. Biol. Chem. 282: 27693-27701.

Jones H.S., Kawauchi J., Braglia, P., Alén C., Kent N.A. & Proudfoot N. (2007) RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA. Nat. Struct. Mol. Biol. 14:123-130.

Sherriff, J., Kent N.A. & Mellor J. (2007) The Isw2 chromatin remodeling ATPase cooperates with the Fkh2 transcription factor to represses transcription of the B-type cyclin CLB2. Mol. Cell. Biol. 27:2848-2860.

Kent N.A., Eibert S.M., & Mellor J. (2004). Cbf1p is required for chromatin remodeling at promoter-proximal CACGTG motifs in yeast. J. Biol. Chem. 279:27116-27123.

Martinez-Campa C., Politis P., Moreau J-L., Kent N., Goodall J., Mellor J. & Goding C.R. (2004) Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromo-domain factor Bdf1. Mol. Cell 15: 69-81.

Ferreiro J., Powell N., Karabetsou N., Kent N., Mellor E. & Waters R. (2004) Cbf1p influences chromatin structure, transcription and repair at the S. cerevisiae MET16 locus. Nucleic Acids Res. 32:1617-1626.

Morillon A., Karabetsou N., O’Sullivan J., Kent N., Proudfoot N. & Mellor J. (2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115: 425-435.

Alen C., Kent N.A., Jones H.S., O’Sullivan J., Aranda A. & Proudfoot N. (2002) A role for chromatin remodeling in transcriptional termination by RNA polymerase II. Mol. Cell 10: 1441-1452.

Kent N.A., Karabetsou N., Politis P.K., & Mellor J. (2001). In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p. Genes Dev. 15: 619-626.