Dr Nicholas A. Kent - DPhil
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Link to ScopusTM Database
Selected Publications
Kent NA, Adams S, Moorhouse A and Paszkiewicz K (2010) Chromatin particle spectrum analysis: a method for comparative chromatin structure analysis using paired-end mode next-generation DNA sequencing. Nucleic Acids Research doi:10.1093/nar/gkq1183.
Loney ER, Inglis PW, Sharp S, Pryde FE, Kent NA, Mellor J and Louis EJ (2009) Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae. Epigenetics and Chromatin 2:18.
Kent NA, Chambers AL and Downs JA (2007) Dual chromatin remodelling roles for RSC during DNA double-strand break induction and repair at the yeast MAT locus. Journal of Biological Chemistry 282:27693-27701.
Jones HS, Kawauchi J, Braglia P, Alen C, Kent NA and Proudfoot N (2007) RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA. Nature Structural and Molecular Biology 14:123-130.
Sherriff J, Kent NA and Mellor J (2007) The Isw2 chromatin remodeling ATPase cooperates with the Fkh2 transcription factor to represses transcription of the B-type cyclin CLB2. Molecular and Cellular Biology 27:2848-2860.
Kent NA, Eibert SM and Mellor J (2004). Cbf1p is required for chromatin remodeling at promoter-proximal CACGTG motifs in yeast. Journal of Biological Chemistry 279:27116-27123.
Martinez-Campa C, Politis P, Moreau J-L, Kent N, Goodall J, Mellor J and Goding CR (2004) Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromo-domain factor Bdf1. Molecular Cell 15: 69-81.
Ferreiro J, Powell N, Karabetsou N, Kent N, Mellor E and Waters R (2004) Cbf1p influences chromatin structure, transcription and repair at the S. cerevisiae MET16 locus. Nucleic Acids Research 32:1617-1626.
Morillon A, Karabetsou N, O'Sullivan J, Kent N, Proudfoot N and Mellor J(2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115: 425-435.
Alen C, Kent NA, Jones HS, O'Sullivan J, Aranda A and Proudfoot N (2002) A role for chromatin remodeling in transcriptional termination by RNA polymerase II. Molecular Cell 10: 1441-1452.
Kent NA, Karabetsou N, Politis PK and Mellor J (2001) In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p. Genes and Development 15: 619-626.