School of Biosciences

Research Overview

The Lung & Particles Research Group (LPRG) specialises in ‘Molecular Environmental Health’. The principal research focus is the determination of intelligent biomarkers of exposure and harm in the human respiratory system following exposure to aerial xenobiotics. Our particular interest lies in understanding how pollutants (e.g. man-made, biological, natural and industrial) compromise lung biochemistry/metabolism and alter gene and protein expression to drive disease mechanisms. Our key research tool involves the generation of human tissue equivalents of the respiratory epithelia, derived from the stem cell niche of patient donor tissue samples, as an alternative platform to animal models.

Research Division

Organisms & Environment