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Macular Research Group

Macular disease is the leading cause of visual impairment in the developed world and currently affects about 500,000 people in the UK. The Macular Research Unit evaluates new methods of detecting, monitoring and treating this condition.

The Macular Research Unit is interested in developing new methods and techniques for the detection, monitoring and diagnosis of macular disease which accounts for 57% of all visual impairment in the UK.

About Macular disease

The light sensitive film at the back of the eye is called the retina and at its centre there exists a highly specialised area which lets us see fine detail and colour known as the macula. Macular disease damages this central part of the retina and can make activities such as reading, driving and recognising faces very difficult.

Get involved

At the heart of the Research Unit are a group of people with macular disease themselves. Over the years they have helped us with numerous studies which have helped us progress this area of research and we are grateful for their support.

If you have macular disease, good vision in at least one eye and would like to help with our research we would love to hear from you. You can get in contact by phoning +44 (0)29 20876118 and asking for Tom Margrain.

Key information

Associated academic staff 6
Postgraduate students 6
Funding £1.4m
Number of invited lectures 5
Publications 60

The Macular Research Unit is interested in developing new methods and techniques for the detection, monitoring and diagnosis of macular disease. Potentially helpful new treatments for macular disease are being found all the time but working out if they really are effective is a major challenge. The Group is keen to support evaluation of these unproven therapies and welcome collaborations with other academic groups and health care provider

Selected publications

Projects (since 2010):

  • Does rehabilitation officer input improve quality of life outcome in patients with low vision: a pilot study
  • Evaluation of the Macular Integrity Assessment microperimeter
  • Multispectral Imaging Retinal Densitometer
  • Net Mobility
  • Ophthalmology Research in Wales
  • Imaging Densitometry
  • Night Lights for AMD: a randomised controlled trial
  • Hypoxia in age-related macular degeneration
  • Evaluating Eccentric Viewing and Steady Eye Technique Training
  • Development of an imaging retinal densitometer
  • Depression in Visual Impairment Trial (DEPVIT)
  • The application of spatial filtering to microperimetry in age-related macular degeneration
  • A microperimetric evaluation of age-related macular degeneration and polypoidal choroidal vasculopathy
  • An investigation of the relationship between retinal structure and dark adaption in humans
  • Quality of life and clinical outcomes in age-related macular degeneration
  • Functional biomarkers of hypoxia in early age-related macular degeneration
  • Assessing Retinal Function in a Genetic Disease Using Electrophysiology
  • An in vivo investigation of choroidal vasulature in age-related macular degeneration

Academic staff

Professor Tom Margrain

Professor Tom Margrain

Director of Research

+44 29208 76118
Dr Ashley Wood

Dr Ashley Wood


+44 29208 75063
Dr Jennifer Acton

Dr Jennifer Acton

Senior Lecturer & Director of Recruitment and Admissions

+44 (0)29 2087 0203
Professor John Wild

Professor John Wild

Head of School, School of Optometry and Vision Sciences

+44 29208 76487
Dr Malgorzata Rozanowska

Dr Malgorzata Rozanowska

Senior Lecturer

+44 29208 75057