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Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre (CREATE)

The Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre works alongside volunteer patients from Cardiff and the Vale University Health Board, to develop and test drugs to treat patients with Rheumatoid and Psoriatic arthritis.

The CREATE Centre is part of the Rheumatology section within the School of Medicine.

We work alongside volunteer patients from Cardiff and the Vale University Health Board, to develop and test drugs to treat patients with Rheumatoid and Psoriatic arthritis. We are jointly funded by Arthritis Research UK, Health and Care Research Wales and Cardiff University.

Rheumatoid and Psoriatic Arthritis are chronic inflammatory joint conditions that result in pain, disability, joint damage and reduced quality of life. Achieving and sustaining remission has been shown to be important in arresting joint damage and improve prognosis. However, the percentage of patients who attain remission in clinical practice is estimated to be less than 30 per cent.

Aims

  • To improve the outcome of patients with rheumatoid and psoriatic arthritis by developing new treatments and diagnostic tests that will lead to more patients achieving disease remission.

If you would like to find out more about the centre or are interested in engaging with us please contact us by email.

We have established collaboration with other researchers in the area of infection and immunity to identify novel targets and develop new treatment.

Testing these novel treatments in patients with Rheumatoid and Psoriatic Arthritis will be facilitated by the South East Wales Trials Unit and the Clinical Research Facility at University Hospital of Wales.

Selected publications

Contact

Academic staff

Professor Ernest Choy

Professor Ernest Choy

Clinical Professor

Email
choyeh@cardiff.ac.uk
Telephone
+44 (0)29 2068 7092
Professor Simon Jones

Professor Simon Jones

Dean of Research; Co-Director of Systems Immunity Research Institute; Research Theme Lead - Infection, Inflammation & Immunity

Email
jonessa@cardiff.ac.uk
Telephone
+44 (0)29 2068 7325
Professor Anwen Williams

Professor Anwen Williams

Professor of Experimental Pharmacology and Therapeutics, Director of Organisation and Wellbeing

Email
williamsas@cardiff.ac.uk
Telephone
+44 (0)29 2074 4733
Dr Rebecca Playle

Dr Rebecca Playle

Reader and Deputy Director of Statistics

Welsh speaking
Email
playlera@cardiff.ac.uk
Telephone
+44 (0)29 2074 4821
Timothy Pickles

Timothy Pickles

NIHR Doctoral Fellow

Email
pickleste@cardiff.ac.uk
Telephone
+44 (0)29 2068 7259

Associated staff

Professor George Schett

University or Erlangen Nuremberg

Dr Paul-Peter Tak

GlaxoSmithKline

Dr Jeremy Camilleri

Cardiff and Vale University Health Board

Dr Sharon Jones

Cardiff and Vale University Health Board

Dr Julian Nash

Cardiff and Vale University Health Board

Dr Anurag Negi

Cardiff and Vale University Health Board

Professor Maurice Hallett

Professor Maurice Hallett

Emeritus Professor

Email
hallettmb@cardiff.ac.uk
Telephone
+44 292074 2748
Professor Paul Morgan

Professor Paul Morgan

'Professor of complement biology, Division of Infection and Immunity

Email
morganbp@cardiff.ac.uk
Telephone
+44 (0)29 2068 7096
Professor Eddie Wang

Professor Eddie Wang

Professor of Viral Immunology

Email
wangec@cardiff.ac.uk
Telephone
+44 (0)29 2068 7035