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ChIP-seq

Chromosomes are chemically treated in vivo to crosslink DNA and chromatin proteins.

RNA-seq

Complex mixtures of RNA molecules from cells and tissues are converted into cDNA and then subjected to Illumina NGS.

Chromatin-seq

Chromosomal DNA can be digested in vivo with exogenously-added nuclease enzymes such as micrococcal nuclease (MNase).

Genome sequencing

The millions of short sequence reads derived from Illumina sequencing of genomic DNA fragments can be analysed in many different ways.

Metagenomics

Complex mixtures of genomic DNA isolated from eco-system sources, such as gut bacteria or soil samples, can be sequenced, and metagenomic analysis performed to infer community structure.

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