Genome sequencing

The millions of short sequence reads derived from Illumina sequencing of genomic DNA fragments can be analysed in many different ways. Novel genome sequences can be assembled entirely de novo for relatively simple organisms (e.g. bacteria and archaea), or into contigs for eukaryotic organisms. Known genomes can be re-sequenced, and when compared to references, used to discover mutations.

In addition to sequencing, the GRH offers manual DNA library contruction (using Illumina, NEB, Rubicon or Bioo Scientific) reagents for up to 192 samples per sequencing run. We can also offer automated TruSeq Nano DNA library preps for up to 24 samples using the NeoPrep.