The Electric Brain: Modelling and Measuring

The human brain is an extraordinarily complex system, composed of billions of cells interacting through intricate electrical currents.

Accurate characterisation of endogenous current generators is critical for understanding the brain's function in both health and disease. Our group, based at CUBRIC, is dedicated to advancing non-invasive techniques for studying neurophysiological activity and precisely localising brain activity from recordings.

Using state-of-the-art equipment, we develop cutting-edge methods to reconstruct brain current generators from various types of acquisitions, focusing primarily on electroencephalography (EEG) and magnetoencephalography (MEG). Our work spans the entire research pipeline, from equipment design to the development of computational head models essential for these tasks and their clinical applications.

The group is internationally recognised for its expertise in creating novel numerical tools to simulate E/MEG signals tailored to specific challenges. We also integrate complementary techniques, such as electrical impedance tomography (EIT), to enhance the reliability and accuracy of our findings.

In addition, we focus on optimising measurement acquisition processes, with particular emphasis on the use of portable optically pumped magnetometers (OPMs). This approach enables more flexible, precise, and accessible studies of brain activity, broadening the potential applications of our research and technologies.