Dr Robert Andrews

2022

• Takala, R. et al. 2022. Pinolenic acid exhibits Anti-inflammatory and Anti-atherogenic effects in Peripheral blood- derived Monocytes from patients with Rheumatoid Arthritis. Scientific Reports 12, article number: 8807. (10.1038/s41598-022-12763-8)
• Takala, R. et al. 2022. Pinolenic acid exhibits anti-inflammatory and anti-atherogenic effects in peripheral blood-derived monocytes from patients with rheumatoid arthritis. Scientific Reports 12, article number: 8807. (10.1038/s41598-022-12763-8)
• Ponsford, M. J. et al. 2022. Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation. Journal of Clinical Pathology 75(4), pp. 255-262. (10.1136/jclinpath-2020-207157)
• Takala, R., Ramji, D. P., Andrews, R., Zhou, Y., Burston, J. and Choy, E. 2022. Anti-inflammatory and immunoregulatory effects of pinolenic acid in rheumatoid arthritis. Rheumatology 61(3), pp. 992-1004. (10.1093/rheumatology/keab467)
• Khan, U. B., Jauneikaite, E., Andrews, R., Chalker, V. J. and Spiller, O. B. 2022. Identifying large-scale recombination and capsular switching events in Streptococcus agalactiae strains causing disease in adults in the UK between 2014 and 2015. Microbial Genomics 8(3), article number: 783. (10.1099/mgen.0.000783)
• Misheva, M. et al. 2022. Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation. Nature Communications 13(1), article number: 139. (10.1038/s41467-021-27766-8)

2021

• Chakraborty, M. et al. 2021. nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis-protocol for a prospective multicohort study. BMJ Open 11(12), article number: e050100. (10.1136/bmjopen-2021-050100)
• Lu, Y. et al. 2021. Single-nucleus RNA sequencing identifies new classes of proximal tubular epithelial cells in kidney fibrosis. Journal of the American Society of Nephrology 32(10), pp. 2501-2516. (10.1681/ASN.2020081143)
• Jones, R. E., Andrews, R., Holmans, P., Hill, M. and Taylor, P. R. 2021. Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer's disease. Scientific Reports 11(1), article number: 14935. (10.1038/s41598-021-94324-z)
• Hrastelj, J. et al. 2021. CSF-resident CD4+ T-cells display a distinct gene expression profile with relevance to immune surveillance and multiple sclerosis. Brain Communications (10.1093/braincomms/fcab155)
• Khalid, U. et al. 2021. Determination of a microRNA signature of protective kidney ischemic preconditioning originating from proximal tubules. Scientific Reports 11(1), article number: 9862. (10.1038/s41598-021-89195-3)
• Sands, K. et al. 2021. Characterization of antimicrobial resistant Gram-negative bacteria that cause neonatal sepsis in seven low and middle-income countries. Nature Microbiology 6, pp. 512–523. (10.1038/s41564-021-00870-7)
• Crittenden, S. et al. 2021. Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells. Science Advances 7(7), article number: eabd7954. (10.1126/sciadv.abd7954)
• Tyrrell, V. J. et al. 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62, article number: 100094. (10.1016/j.jlr.2021.100094)

2020

• Pires, A. et al. 2020. Immune remodelling of the extracellular matrix drives loss of cancer stem cells and tumor rejection. Cancer Immunology Research 8(12), pp. 1520 - 1531. (10.1158/2326-6066.CIR-20-0070)
• Greenshields-Watson, A. et al. 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32(2), article number: 107885. (10.1016/j.celrep.2020.107885)
• Meckelmann, S. W. et al. 2020. Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274. Circulation: Genomic and Precision Medicine 13(3), pp. 149-164., article number: e002806. (10.1161/CIRCGEN.119.002806)
• Scurr, M. J. et al. 2020. Cancer antigen discovery is enabled by RNA-sequencing of highly purified malignant and non-malignant cells. Clinical Cancer Research (10.1158/1078-0432.CCR-19-3087)

2019

• Thompson, A. et al. 2019. The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors. PLoS Pathogens 15(6), article number: e1007850. (10.1371/journal.ppat.1007850)
• Twohig, J. P. et al. 2019. Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature Immunology 20, pp. 458-470. (10.1038/s41590-019-0350-0)
• Allen-Redpath, K. et al. 2019. Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity. Proceedings of the National Academy of Sciences 116(16), pp. 8038-8047. (10.1073/pnas.1814409116)
• Liu, Z. et al. 2019. Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p. Cell Death and Disease 10, article number: 55. (10.1038/s41419-018-1287-1)
• Lear, B. et al. 2019. De novo transcriptome analysis of peduncle necking in cut Rosa hybrida cultivar 'H30'. Acta Horticulturae 1263, pp. 351-358.

2018

• Kentala, H. et al. 2018. OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism. Cellular and Molecular Life Sciences 75(21), pp. 4041-4057.
• McCully, M. L. et al. 2018. CCR8 expression defines tissue-resident memory T cells in human skin. Journal of Immunology 200(5), pp. 1639-1650. (10.4049/jimmunol.1701377)
• McNamara, G. I., Creeth, H. D. J., Harrison, D. J., Tansey, K. E., Andrews, R. M., Isles, A. R. and John, R. M. 2018. Loss of offspring Peg3 reduces neonatal ultrasonic vocalizations and increases maternal anxiety in wild-type mothers. Human Molecular Genetics 27(3), pp. 440-450. (10.1093/hmg/ddx412)
• Kentala, H., Koponen, A., Kivelä, A. M., Andrews, R., Li, C., Zhou, Y. and Olkkonen, V. M. 2018. Analysis of ORP2 knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation. FASEB Journal (10.1096/fj.201700604R)

2017

• Dovey, O. M. et al. 2017. Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia. Blood 130(17), pp. 1911-1922. (10.1182/blood-2017-01-760595)
• Fisher, C., Andrews, R. and Skarnes, W. 2017. An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Research (10.1093/nar/gkx811)
• Liao, C. et al. 2017. Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes. Kidney International 91(5), pp. 1088-1103. (10.1016/j.kint.2016.10.030)