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Stem cells, regeneration and repair

Stem Cell

Our research is aimed at understanding the causes of ocular degeneration and the development of novel eye care treatments and products for improved ocular health.

To address the world-wide shortage of corneal donor tissue for the treatment of corneal disorders and pathologies, we have joined forces with Linkoping University, the University of Montreal and LV Prasad Eye Institute, in an international collaborative effort to develop a suitable artificial corneal replacement.

We also continue to collaborate closely with clinician-scientists in Osaka University to harness the power of human induced pluripotent stem (iPS) cells to generate transplantable eye tissue capable of restoring visual function.

In the field of glaucoma and inherited optic neuropathy, our research investigates novel therapeutic agents, which include adult stem cells, as well as their secreted constituents (e.g. exosomes). We test these novel neuroprotective therapeutic strategies in state-of-the-art in vitro and in vivo models, and human embryonic stem cell-derived retinal cultures.

Staff members

Professor Keith Meek

Professor Keith Meek

Head of Biophysics Research Group, Emeritus Professor

Email
meekkm@cardiff.ac.uk
Telephone
+44 (0)29 2087 6317
Professor Andrew Quantock

Professor Andrew Quantock

Professor

Email
quantockaj@cardiff.ac.uk
Telephone
+44 (0)29 2087 5064
Professor Marcela Votruba

Professor Marcela Votruba

Professor and Hon. Consultant in Ophthalmology

Email
votrubam@cardiff.ac.uk
Telephone
+44(0)29 2087 0117
Dr James Bell

Dr James Bell

Research Associate

Email
bellj10@cardiff.ac.uk
Telephone
+44 (0)29 2087 6356
Dr Sally Hayes (née Dennis)

Dr Sally Hayes (née Dennis)

Research Fellow

Email
hayess5@cardiff.ac.uk
Telephone
+44 (0)29 208 70459
Dr Elena Koudouna

Dr Elena Koudouna

Marie Skłodowska-Curie Fellow

Email
koudounae@cardiff.ac.uk
Telephone
+44 (0)29 20870205
Dr Philip Lewis

Dr Philip Lewis

Research Fellow and Electron Microscopy Specialist

Email
lewispn@cardiff.ac.uk
Telephone
+44 (0)29 208 70459
Dr Ben Mead

Dr Ben Mead

Lecturer

Email
meadb@cardiff.ac.uk
Telephone
+44(0)29 2087 0502
Dr Sian Morgan

Dr Sian Morgan

Research Associate

Email
morgans51@cardiff.ac.uk
Telephone
+44 (0)29 2087 6356
Dr Rob Young

Dr Rob Young

Research Fellow

Email
youngrd@cardiff.ac.uk
Telephone
+44 29208 70205

Research groups

Our stem cells, regeneration and repair research is pursued within three collaborative groups: