Dr Tom Massey

Articles

• Taylor, A. et al. 2022. Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR Genomics and Bioinformatics 4(4), article number: lqac089. (10.1093/nargab/lqac089)
• Lobanov, S. et al. 2022. Huntington’s disease age at motor onset is modified by the tandem hexamer repeat in TCERG1. npj Genomic Medicine 7, article number: 53. (10.1038/s41525-022-00317-w)
• Lee, J. et al. 2022. Genetic modifiers of Huntington disease differentially influence motor and cognitive domains. American Journal of Human Genetics 109(5), pp. 885-899. (10.1016/j.ajhg.2022.03.004)
• Cooper, M., Gale, K., Langley, K., Broughton, T., Massey, T. H., Hall, N. J. and Jones, C. R. 2022. How to do it: the neurological consultation with an autistic patient. Practical Neurology 22, pp. 120-125. (10.1136/practneurol-2020-002856)
• McAllister, B. et al. 2022. Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature Neuroscience 25, pp. 446-457. (10.1038/s41593-022-01033-5)
• Steventon, J. et al. 2021. Changes in white matter microstructure and MRI-derived cerebral blood flow after one-week of exercise training. Scientific Reports 11, article number: 22061. (10.1038/s41598-021-01630-7)
• Massey, T. H. and Robertson, N. P. 2021. Medication-overuse headache: causes, consequences and management. Journal of Neurology 268(9), pp. 3505–3507. (10.1007/s00415-021-10720-5)
• McAllister, B. et al. 2021. Timing and impact of psychiatric, cognitive, and motor abnormalities in Huntington disease. Neurology 96(19), pp. e2395-e2406. (10.1212/WNL.0000000000011893)
• Hong, E. P. et al. 2021. Association analysis of chromosome X to identify genetic modifiers of Huntington's disease. Journal of Huntington's Disease 10(3), pp. 367-375. (10.3233/JHD-210485)
• Cunningham, A., Fung, W., Massey, T., Hall, J., Owen, M., Van Den Bree, M. and Peall, K. 2020. Movement disorder phenotypes in children with 22q11.2 deletion syndrome. Movement Disorders 35(7), pp. 1272-1274. (10.1002/mds.28078)
• Ellis, N. et al. 2020. Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry 87(9), pp. 857-865. (10.1016/j.biopsych.2019.12.010)
• Massey, T. H. and Robertson, N. P. 2020. Restless legs syndrome: causes and consequences. Journal of Neurology 267(2), pp. 575-577. (10.1007/s00415-019-09682-6)
• Lee, J. et al. 2019. CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell 178(4), pp. 887-099.e14. (10.1016/j.cell.2019.06.036)
• Cronin, T., Rosser, A. and Massey, T. 2019. Clinical presentation and features of Juvenile-onset Huntington's disease: a systematic review. Journal of Huntington's Disease 8(2), pp. 171-179. (10.3233/JHD-180339)
• Massey, T. and Robertson, N. 2018. Repurposing drugs to treat neurological diseases. Journal of Neurology 265(2), pp. 446-448. (10.1007/s00415-018-8732-z)
• Massey, T. and Jones, L. 2018. The central role of DNA damage and repair in CAG repeat diseases. Disease Models & Mechanisms 11(1), article number: dmm031930. (10.1242/dmm.031930)
• Holmans, P. A., Massey, T. H. and Jones, L. 2017. Genetic modifiers of Mendelian disease: Huntington's disease and the trinucleotide repeat disorders. Human Molecular Genetics 26(R2), pp. R83-R90. (10.1093/hmg/ddx261)
• van de Zande, N. A. et al. 2017. Clinical characterization of dystonia in adult patients with Huntington's disease. European Journal of Neurology 24(9), pp. 1140-1147. (10.1111/ene.13349)
• Massey, T. and Robertson, N. 2017. Why antisense could make sense for neurodegeneration. Journal of Neurology 264(7), pp. 1542-1544. (10.1007/s00415-017-8515-y)
• Massey, T., Smith, R., Sadiq Shaheena, S., Overton, C. and Pearson, O. R. 2017. Rescue of severe brain and cervical cord IRIS by restarting natalizumab in a pregnant MS patient. Neurology 88(7), pp. 711-713. (10.1212/WNL.0000000000003604)
• Massey, T. and Robertson, N. 2016. Zika virus and neurology: proving cause and effect. Journal of Neurology 263(6), pp. 1255-1257. (10.1007/s00415-016-8165-5)
• Massey, T., Pickersgill, T. T. and Peall, K. J. 2016. Nitrous oxide misuse and vitamin B12 deficiency. BMJ Case Reports, article number: 215728. (10.1136/bcr-2016-215728)

Book sections

• Massey, T., McAllister, B. and Jones, L. 2018. Methods for assessing DNA repair and repeat expansion in Huntington's Disease. In: Precious, S. V., Rosser, A. E. and Dunnett, S. B. eds. Huntington’s Disease., Vol. 1780. Methods in Molecular Biology Humana Press, pp. 483-495., (10.1007/978-1-4939-7825-0_22)

Websites

• McAllister, B. et al. 2020. The onset and prevalence of motor and psychiatric symptoms in Huntington’s disease. [Online]. bioRxiv. (10.1101/2020.05.26.116798)