Ewch i’r prif gynnwys

Dr Laura Thomas

BSc, PhD

Research Associate

Yr Ysgol Meddygaeth

Email
thomasl41@cardiff.ac.uk
Telephone
+44 (0)29 2251 0025 / (0)29 2068 7859
Campuses
1F.08, 1st floor, Adeilad Geneteg Canser, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4XN
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Trosolwg

As part of the Inherited Tumour Syndrome Research Group, I have a particular interest in intestinal polyposis syndromes, specifically polyposis of the duodenum and colorectum. The aim of my research is to develop new methods and techniques for mutation detection and to characterise inherited and somatic genetic mechanisms in patients with inherited tumour syndromes.

Cyhoeddiadau

2022

2020

2018

2017

2015

2012

2011

2010

Addysgu

Current research students:

  • Emma Short, PhD (2013-2018)  
    • 'Genetic mechanisms in polyposis of the bowel' 
  • Elena Meuser, PhD (2015-2018)  
    • 'Molecular mechanisms of tumorigenesis in familial polyposis syndromes
  • Beth Bradford, Undergraduate placement student (2016-2017) 
    • 'Genetic mechanisms in colorectal and duodenal polyposis' 

Previous students:

  • Joanna Hurley, MD (2012-2015)
    • 'Molecular genetic and endoscopic studies of duodenal polyposis in the inherited colorectal adenoma and cancer predisposition syndromes (Familial Adenomatous Polyposis and MUTYH-Associated Polyposis)'

My research interests involve the use of high throughput genomic technologies to determine the molecular mechanisms underlying rare genetic disorders and tumour predisposition syndromes. 

My research is funded by a Health and Care Research Wales Fellowship.

Research studies in which I am currently involved include:

  • Molecular genetic analysis of duodenal polyposis in the inherited colorectal adenoma and cancer predisposition syndromes (Familial Adenomatous Polyposis and MUTYH-Associated Polyposis) (15/WA/0075. CRNCC ID, 19065) [Chief Investigator]

  • Genetic mechanisms in polyposis of the bowel (12/WA/0071. CRNCC ID, 14774) 

  • A Prospective Europe-Wide Study of Duodenal Disease in MUTYH-Associated Adenomatous Polyposis (MAP).(11/WA/0208)

Proffiliau allanol