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Dr Emma Kidd's publications

 

Peer reviewed articles(2000-2010)

 

Thomas, R.S., Liddell, J.E. and Kidd, E.J. (2010). Anti-amyloid-β protein precursor antibodies inhibit amyloid-β production by steric hindrance. FEBS Journal, DOI: 10.1111/j.1742-4658.2010.07942.x.

Broadley, K.J., Blair, A.E., Kidd, E.J. Bugert, J.J. and Ford, W.R., (2010). Bradykinin-induced lung inflammation and bronchoconstriction: role in PIV-3-induced inflammation and airways hyperreactivity. J. Pharmacol. Exp. Ther., doi:10.1124/jpet.110.171876.

Fehler, M., Broadley, K.J., Ford, W.R., and Kidd, E.J. (2010). Identification of trace amine-associated receptors (TAAR) in the aorta and their role in vasoconstriction by β-phenylethylamine. Naunyn Schmeideberg’s Arc. Pharmacol., 382, 385-398.

Turner, D.L., Ferrari, N., Ford, W.R., Kidd, E.J., Paquet, L., Renzi P. and Broadley K.J. (2010). TPI 1020, a novel anti-inflammatory, nitric oxide donating compound, potentiates the bronchodilator effects of salbutamol. Eur. J. Pharmacol., 641, 213-219.

Fernandez-Rodriguez, S., Broadley, K.J., Ford, W.R. and Kidd, E.J. (2010). Increased muscarinic receptor sensitivity of airway smooth muscle isolated from a mouse model of allergic asthma. Pulmonary Pharmacology & Therapeutics, 23, 300-307.

Broadley, K.J., Anwar, M.A., Herbert, A.A., Fehler, M., Jones, E.M., Davies, W.E., Kidd, E.J. and Ford, W.R. (2009). Effects of dietary amines on the gut and its vasculature. Br. J. Nutrition, 101, 1645-1652.

Alqallaf, S.M., Evans, B.A.J. and Kidd, E.J. (2009). Atypical P2X7 receptor pharmacology in two human osteoblast-like cell lines. Br. J. Pharmacol., 156, 1124-1135.

Penson, P.E., Ford, W.R., Kidd, E.J. and Broadley, K.J. (2008). Activation of β-adrenoceptors mimics preconditioning of isolated atria and ventricles against ischaemic contractile dysfunction. Naunyn-Schmiedeberg's Arch. Pharmacol., 378, 589-597.

Herbert, A.A, Kidd, E.J. and Broadley, K.J. (2008). Dietary trace amine dependent vasoconstriction in porcine coronary artery. Br. J. Pharmacol., 155, 525-534.

Fernandez-Rodriguez, S., Ford, W.R., Broadley, K.J. and Kidd, E.J. (2008). Establishing the phenotype in novel acute and chronic murine models of allergic asthma. International Immunopharmacology, 8, 756-763.

Thomas, R.S., Liddell, J.E., Murphy, L., Pache, D. and Kidd, E.J. (2006). An antibody to the β-secretase cleavage site on amyloid b-precursor protein inhibits amyloid β production. J. Alzheimer’s Disease, 10, 379-390.

Yates, L., Clark, J.H., Martin, T.J., Broadley, K.J. and Kidd, E.J., (2006). Radioligand binding and functional response of ligands for human recombinant adenosine A3 receptors. Autonomic and Autocoid Pharmacol., 26, 191-200.

Connon, C.J., Young, R.D. and Kidd, E.J. (2003). P2X7 receptors are redistributed on human monocytes after pore formation in response to prolonged agonist exposure. Pharmacology, 67, 163-168.

Elneil, S., Skepper, J.N., Kidd, E.J., Williamson, J.G. and Ferguson, D.R. (2001).  The distribution of P2X1 and P2X3 purinoceptors in the rat and human urinary bladder. Pharmacology, 63, 120-128.

Souslova, V., Cesare, P., Ding, Y., Akopian, A.N., Stanfa, L., Suzuki, R., Carpenter, K., Dickenson, A., Boyce, S., Hill, R., Nebenius-Oosthuizen, D., Smith, A.J.H., Kidd, E.J. and Wood, J.N. (2000).  Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors.  Nature, 407, 1015-1017.

Hibell, A.D., Michel, A.D., Kidd, E. J., Chessell, I.C. and Humphrey, P.P.A (2000).  Apparent species differences in the kinetic properties of P2X7 receptors.  Br. J. Pharmacol., 130, 167-173.

 

Books and book chapters

Laporte, A.M., Kidd, E., Vergé, D., Gozlan, H. and Hamon, M. (1992).  Autoradiographic mapping of central 5-HT3 receptors.  In 'Central and Peripheral 5-HT3 Receptors', (Hamon, M., Ed.), Academic Press, London, 157-187.

Kidd, E., Laporte, A.M., Langlois, X., Lombard, M.C., Gozlan, H. and Hamon, M. (1992).  Differential localization and regulation of central 5-HT1A and 5-HT3 receptors.  In '5-Hydroxytryptamine : CNS Receptors and Brain Functions', (Bradley, P.B., Ed.), Advances in Biosciences, Pergamon Press, 85, 13-27.

Hamon, M., Kidd, E.J., Gozlan, H. and Martin, P. (1991).  Is 5-HT3 receptor blockade able to prevent dopaminergic activation by stress?  Biological Psychiatry, (Racagni, G., Brunello, N. and Fukada, T., Eds.), Elsevier Science Publications, Amsterdam, Vol. 2, 706-709.

Hamon, M., Lanfumey, L., Haj-Dahmane, S., Jolas, T., Kidd, E., Bolaños, F. and Gozlan, H. (1991).  Adaptation of central 5-HT1A receptors after chronic antidepressant treatment in rats.  Biological Psychiatry, (Racagni, G., Brunello, N. and Fukada, T., Eds.), Elsevier Science Publications, Amsterdam, Vol. 1, 297-300.

 

Online Journals

 

Thomas, R.S. and Kidd, E.J. (2010). Targeting amyloid production with antibodies. Alzheimer’s Society Research Newsletter, February 2010, http://www.alzheimers.org.uk/site/scripts/download_info.php?fileID =844

Thomas, R.S., Liddell, J.E., and Kidd, E.J. (2007). Immunotherapy and Alzheimer's disease. The Journal of Quality Research in Dementia, Issue 4, 12.09.07, http://www.qrd.alzheimers.org.uk/onlinejournal/.

 

Abstracts and Conference Proceedings (2000-2010)

 

Ford, W.R., Herbert, A., Kidd, E.J. and Broadley, K.J. (2009). Parainfluenza 3 viral exacerbation of ovalbumin-induced pulmonary inflammation is resistant to fluticasone. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol7Issue2abst016P.pdf.

Henney, N.C., Kidd, E.J., Evans, B.A.J. and Wann, K.T. (2009). TRPV1b is expressed and may assist in pH ‘switching’ of human osteoblasts. Calcified Tissue International, abstract P042.

Turner, D., Kidd, E. Ford, W., Ferrari, N., and Broadley, K. (2009). The bronchodilator effects of the novel anti-inflammatory compound TPI 1020, alone and in combination with formoterol. Eur. Resp. J., .34, abstract 3236.

Thomas, R.S., Liddell, J.E., and Kidd, E.J. (2009). Comparison of anti-b-secretase cleavage site antibodies and their effect on amyloid-b. International Conference on Alzheimer’s Disease, Vienna July 2009, P3-277.

Broadley, K.J., John, E., Blair, A., Bugert, J.J., Kidd, E.J. and Ford, W.R. (2009). Evidence of steroid resistance of airways responses to allergen induced by virus inoculation. Am. J. Respir. Crit. Care Med., Apr 2009;179, A4250.

Turner, D.L., Ferrari, N., Kidd, E.J., Ford, W.R., and Broadley, K.J. (2009). The individual and combined bronchodilator effects of the novel anti-inflammatory compound TPI 1020 and tiotropium. Am. J. Respir. Crit. Care Med., Apr 2009;179, A4563.

Turner, D.L., Ferrari, N., Ford, W.R., Kidd, E.J., Paquet, L. and Broadley, K.J. (2009). The individual and combined bronchodilator effects of the novel anti-inflammatory compound TPI 1020 and salbutamol.  Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol6Issue4abst023P.pdf

Henson, A., Simons, C., Hutcheson, I. and Kidd, E.J. (2010). The Differential effects of clofarabine on breast cancer cell proliferation. BACR meeting, Edinburgh, June 2010.

Broadley, K.J., Kidd, E.J. John, E., Corkill, D.J., Evans, D.M., Hampton, S.L. and Ford, W.R. (2010). A Tissue Kallikrein Inhibitor Prevents Steroid-resistant Viral-induced Exacerbations Of Allergen Responses. Am. J. Respir. Crit. Care Med., May 2010; 181: A5592

Evans, R.L., Broadley, K.J., Ford, W.R., Kidd, E.J. and Nials, A. (2009). Structural and functional changes in the airways of acute and chronic murine models of asthma. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol7Issue4abst012P.pdf

Kidd, E.J., Al-qallaf, S.M. and Evans, B.A.J. (2009). P2X7 receptors modulate mineralisation in primary human osteoblasts. Purine Mini-Symposium, Purinergic Signalling, in press, 10.1007/s11302-009-9175-x.

Herbert, A., Kidd, E.J, Ford, W.R. and Broadley, K.J. (2009). Vasoconstriction of porcine coronary artery by amphetamines, including MDMA. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol7Issue2abst028P.pdf.

Evans, R.L., Ford, W.R., Kidd, E.J., Nials, A. and Broadley, K.J. (2009). Effect of fluticasone propionate and roflumilast on acute and chronic  models of asthma. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol6Issue4abst057P.pdf.

Henson, A., Simons, C. and Kidd, E.J. (2009). Anti-proliferative effects of cladribine on human breast MCF-7 adenocarcinoma cells. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol6Issue4abst 147P.pdf

Turner, D.L., Ferrari, N., Ford, W.R., Kidd, E.J., Paquet, L. and Broadley, K.J. (2009). The individual and combined bronchodilator effects of the novel anti-inflammatory compound TPI 1020 and salbutamol in conscious guinea pigs. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol6Issue4abst023P.pdf

Thomas, R.S., Liddell, J.E., and Kidd, E.J. (2008). The mode of action of an anti-ÿ-secretase cleavage site antibody. International Conference on Alzheimer’s Disease, Chicago July 2008, P2-367.

Penson, P.E., Ford, W.R., Kidd, E.J. and Broadley, K.J. (2008). Protective role of β2- and β3- adrenoceptors at reperfusion in isolated rat heart. Journal of Molecular and Cellular Cardiology, 44, 719.

Fehler, M., Kidd, E.J. and Broadley, K.J. (2008). Investigation of Trace Amines Associated Receptors in Rat Aorta. FASEB J., 22, 912.5.

Herbert, A.H., Broadley, K., Kidd, E. and Ford, W. (2008). Trace amine dependent vasoconstriction in porcine coronary artery. FASEB J., 22, 914.5.

Evans, R.L., Ford, W.R., Kidd, E.J. and Broadley, K.J. (2008). Recovery rates from acute and chronic ovalbumin challenge in guinea pigs. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol5Issue2abst 079P.pdf.

Fehler, M., Kidd, E.J. and Broadley, K.J. (2008). Contraction of rat isolated aorta to trace amines independent of adrenoceptor stimulation. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol5Issue2abst 024P.pdf.

Penson, P.E., Ford, W.R., Kidd, E.J. and Broadley, K.J. (2008). Infarct-size reduction induced by ischaemic postconditioning is dependent on β2-adrenoceptor activation in the Langendorff perfused rat heart. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol5Issue2 abst030P.pdf.

Al-qallaf, S.M., Evans, B.A.J. and Kidd, E.J. (2007). Atypical pharmacology of P2X7 receptors in human osteoblasts. J. Bone Miner. Res., 22, 1135

Al-qallaf, S.M., Kidd, E.J. and Evans, B.A.J. (2007). Modulation of P2X7 receptors in human osteoblasts by oestrogen and dexamethasone. J. Bone Miner. Res., 22, Suppl. 1, M055.

Penson, P.E., Ford, W.R., Kidd, E.J. and Broadley, K.J. (2007). Preconditioning by the β-adrenoceptor agonist, isoprenaline, in the rat isolated atrium but not ventricle. Proceedings of the British Pharmacological Society at http://www.pa2online.org/Vol4Issue2abst115P.html.

Fehler, M., Kidd, E.J. and Broadley, K.J. (2007). Contraction of rat isolated aorta to β-phenylethylamine not mediated by adrenoceptors. Proceedings of the British Pharmacological Society at http://www.pa2online.org/Vol4Issue2abst182P.html.

Al-qallaf, S.M., Kidd, E.J., Elford, C. and Evans, B.A.J. (2006). Characterization of P2X7 receptor expression and function in human osteoblasts. J. Bone Miner. Res., 21, 1167.

Fernandez-Rodriguez, S., Broadley, K.J. and Kidd, E.J. (2004). Pharmacology of airway smooth muscle and cell influx in a murine asthma model. European Respiratory Journal, 24, Suppl. 48, 4222, p690s.

Fernandez-Rodriguez, S., Broadley, K.J. and Kidd, E.J. (2003). Pharmacology of tracheal smooth muscle in male and female mice. Proceedings of the British Pharmacological Society at http://www.pa2online.org/Vol1Issue4abst107P.html.

Clark, J.H., Broadley, K.J., Hutcheson, I.R., Nicholson, R.I. and Kidd, E.J. (2003). Expression of adenosine receptors in MCF-7 human breast cancer cells. Br. J. Pharmacol., 138, 130P.

Clark, J.H., Martin, T.J., Yates, L., Kidd, E.J., R. I. Nicholson and Broadley, K.J. (2002). Characterisation of transfected human adenosine A3 receptors. Br. J. Pharmacol., 136, 38P.

Clark, J.H., Broadley, K.J., Hutcheson, I.R., Nicholson, R.I. and Kidd, E.J. (2002). Adenosine receptor agonists mediate the phosphorylation of mitogen activated protein kinase (MAPK) in MCF-7 human breast cancer cells. Br. J. Pharmacol., 135, 46P.

Elneil, S., Skepper, J.N., Kidd, E.J., Williamson, J.G., Sellers, L.A. and Ferguson, D.R. (2001). Evidence for differential expression of P2X1 and P2X3 purine receptors in the detrusor muscle and urothelium, respectively, in the rat and human urinary bladder. Br. J. Pharmacol., 133, 16P.

Simon, J., Michel, A.D., Thompson, K.M., Kidd, E.J., Barnard E.A. and Humphrey, P.P.A. (2000). Expression and functional characterisation of the rat P2X7-GFP chimeric protein. Proceedings of Purines 2000, Biochemical, Pharmacological and Clinical perspectives, International Symposium of Nucleosides and Nucleotides, July 9-13, Madrid, Spain, P038.

Kidd, E.J., Thompson, K.T., Michel, A.D. and Humphrey, P.P.A. (2000). The effect of receptor expression and temperature on agonist potency at the P2X7 receptor assessed using an inducible expression system. Br. J. Pharmacol., 131, 124P.

Kidd, E.J., Michel, A.D., Grahames, C.M., Dawe, H. and Humphrey, P.P.A. (2000). P2X7 receptor expression and function in human THP-1 cells. Br. J. Pharmacol., 131, 107P.

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