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Wales Gene Park Genomic Facility

A member of staff using the equipment
Illumina HiSeq 2500 – A production-scale genome, exome and transcriptome sequencing platform.

Harnessing genetics to advance research, healthcare, education and innovation.

High-throughput (next generation) DNA and RNA sequencing is a rapidly developing technology, of fundamental importance to modern genetics research and biomedical research in particular.

We provide high-throughput sequencing technology and associated bioinformatic analysis for biomedical research in Wales and provide expert support and advice to encourage greater uptake of this fundamental technology.

We work with HEI colleagues to provide expertise and technology at low cost working from project design through to tertiary analysis.

Technical facilities

Genome scale next generation sequencing (NGS)

The WGP Genomic Facility is co-located with the NHS All Wales Medical Genetic Service at the Heath Park site. Through this joint facility we are able to provide access to several NGS platforms:

  • Illumina HiSeq 2500
  • Illumina MiSeq
  • Ion Proton


  • Mammalian Genomes
  • Exomes
  • Targeted Capture
  • RNA Seq
  • Targeted RNA Seq
  • Ultra Deep Sequencing
  • Non standard protocols


We provide colleagues with bioinformatics expertise, training and support, as well as access to dedicated high performance computing.

We have dedicated high performance compute infrastructure and data storage, and are plugged into the Hawk supercomputer to provide additional compute capacity when needed.

  • Compute: 288 cores (Intel Haswell) across 12 compute nodes each with 256 GB memory.
  • Storage: one petabyte resilient storage for long-term storage of genomic Big Data.

How we help

We provide colleagues with a complete pipeline for genomic scale DNA and RNA Sequence analysis. Our team will support your project from initial design through to grant applications, lab work, data generation, primary, secondary and tertiary analysis. We work collaboratively and flexibly with researchers to support research KPIs.

Our funding policy

Wales Gene Park is funded by Welsh Government through Health and Care Research Wales as an infrastructure support group. As such, we operate to recover consumable costs only. We work collaboratively with partners to meet the requirements of each project and deliver mutually beneficial outputs.

Please get in touch with our Operations Manager, Dr Karen Reed, for further information.