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Dr Cherry-Ann Waldron
Research Fellow / Senior Trial Manager
- WaldronC@cardiff.ac.uk
- Neuadd Meirionnydd, Floor 7, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
- Available for postgraduate supervision
Overview
I am a Research Fellow and Senior Trial Manager in the division of Infections, Inflammation & Immunity at the Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University. I am the theme lead for Vascular Conditions.
My research interests include vascular disease, infections, surgical trials, behaviour change, public health and complex interventions.
I have extensive knowledge and experience in trial methodology and research governance.
Publication
2024
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8(1), article number: zrad135. (10.1093/bjsopen/zrad135)
2023
- Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
2022
- Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
- Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
2021
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11, article number: e054618. (10.1136/bmjopen-2021-054618)
- Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
- Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
- Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)
2020
- Roberts, K. et al. 2020. Cost effectiveness of an intervention to increase uptake of hepatitis C virus testing and treatment (HepCATT): cluster randomised controlled trial in primary care. BMJ 368 (10.1136/bmj.m322)
- Horwood, J., Clement, C., Roberts, K., Waldron, C., Irving, W. L., Macleod, J. and Hickman, M. 2020. Increasing uptake of hepatitis C virus infection case-finding, testing, and treatment in primary care: evaluation of the HepCATT (Hepatitis C Assessment Through to Treatment) trial. British Journal of General Practice (10.3399/bjgp20X708785)
- Ambler, G. K., Waldron, C., Contractor, U. B., Hinchliffe, R. J. and Twine, C. P. 2020. Umbrella review and meta-analysis of antiplatelet therapy for peripheral artery disease. British Journal of Surgery 107(1), pp. 20-32. (10.1002/bjs.11384)
2019
- Bosanquet, D. et al. 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9(11), article number: e029233. (10.1136/bmjopen-2019-029233)
2018
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
2017
- Ambler, G. K., Bosanquet, D. C., Brookes-Howell, L., Thomas-Jones, R. E., Waldron, C., Edwards, A. G. K. and Twine, C. P. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18(1), article number: 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
- Chalumeau, M. et al. 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12(2), article number: e0171113. (10.1371/journal.pone.0171113)
2016
- Gkiousias, V., Butler, C. C., Shepherd, V., Kilgour, J. M., Waldron, C., Thomas-Jones, E. and Francis, N. 2016. Parental perceptions and understanding of information provision, management options and factors influencing the decision-making process in the treatment of children with glue ear. International Journal of Pediatric Otorhinolaryngology 89, pp. 6-12. (10.1016/j.ijporl.2016.07.021)
- Hay, A. D. et al. 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14(4), pp. 325-336. (10.1370/afm.1954)
- Hay, A. D. et al. 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20(51) (10.3310/hta20510)
- Roberts, K. et al. 2016. Hepatitis C - assessment to treatment trial (HepCATT) in primary care: study protocol for a cluster randomised controlled trial. Trials 17(1), article number: 366. (10.1186/s13063-016-1501-3)
- Butler, C. C. et al. 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66(648), pp. e516-e524. (10.3399/bjgp16X685873)
- Butler, C. C. et al. 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33(2), pp. 127-132. (10.1093/fampra/cmv104)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
2015
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
2013
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
2012
- Downing, H. et al. 2012. The diagnosis of urinary tract infections in young children (DUTY): Protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute illness. BMC Infectious Diseases 12(1), article number: 158. (10.1186/1471-2334-12-158)
2011
- Waldron, C., van der Weijden, T., Ludt, S., Gallacher, J. E. and Elwyn, G. 2011. What are effective strategies to communicate cardiovascular risk information to patients? A systematic review. Patient Education and Counseling 82(2), pp. 169-181. (10.1016/j.pec.2010.04.014)
- Waldron, C. 2011. Cardiovascular risk prediction: how useful are web-based tools and do risk representation formats matter?. PhD Thesis, Cardiff University.
2010
- Waldron, C., Gallacher, J. E., van der Weijden, T., Newcombe, R. G. and Elwyn, G. 2010. The effect of different cardiovascular risk presentation formats on intentions, understanding and emotional affect: a randomised controlled trial using a web-based risk formatter (protocol). BMC Medical Informatics and Decision Making 10(1), article number: 41. (10.1186/1472-6947-10-41)
Articles
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8(1), article number: zrad135. (10.1093/bjsopen/zrad135)
- Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
- Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
- Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11, article number: e054618. (10.1136/bmjopen-2021-054618)
- Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
- Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
- Roberts, K. et al. 2020. Cost effectiveness of an intervention to increase uptake of hepatitis C virus testing and treatment (HepCATT): cluster randomised controlled trial in primary care. BMJ 368 (10.1136/bmj.m322)
- Horwood, J., Clement, C., Roberts, K., Waldron, C., Irving, W. L., Macleod, J. and Hickman, M. 2020. Increasing uptake of hepatitis C virus infection case-finding, testing, and treatment in primary care: evaluation of the HepCATT (Hepatitis C Assessment Through to Treatment) trial. British Journal of General Practice (10.3399/bjgp20X708785)
- Ambler, G. K., Waldron, C., Contractor, U. B., Hinchliffe, R. J. and Twine, C. P. 2020. Umbrella review and meta-analysis of antiplatelet therapy for peripheral artery disease. British Journal of Surgery 107(1), pp. 20-32. (10.1002/bjs.11384)
- Bosanquet, D. et al. 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9(11), article number: e029233. (10.1136/bmjopen-2019-029233)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
- Ambler, G. K., Bosanquet, D. C., Brookes-Howell, L., Thomas-Jones, R. E., Waldron, C., Edwards, A. G. K. and Twine, C. P. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18(1), article number: 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
- Chalumeau, M. et al. 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12(2), article number: e0171113. (10.1371/journal.pone.0171113)
- Gkiousias, V., Butler, C. C., Shepherd, V., Kilgour, J. M., Waldron, C., Thomas-Jones, E. and Francis, N. 2016. Parental perceptions and understanding of information provision, management options and factors influencing the decision-making process in the treatment of children with glue ear. International Journal of Pediatric Otorhinolaryngology 89, pp. 6-12. (10.1016/j.ijporl.2016.07.021)
- Hay, A. D. et al. 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14(4), pp. 325-336. (10.1370/afm.1954)
- Hay, A. D. et al. 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20(51) (10.3310/hta20510)
- Roberts, K. et al. 2016. Hepatitis C - assessment to treatment trial (HepCATT) in primary care: study protocol for a cluster randomised controlled trial. Trials 17(1), article number: 366. (10.1186/s13063-016-1501-3)
- Butler, C. C. et al. 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66(648), pp. e516-e524. (10.3399/bjgp16X685873)
- Butler, C. C. et al. 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33(2), pp. 127-132. (10.1093/fampra/cmv104)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
- Downing, H. et al. 2012. The diagnosis of urinary tract infections in young children (DUTY): Protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute illness. BMC Infectious Diseases 12(1), article number: 158. (10.1186/1471-2334-12-158)
- Waldron, C., van der Weijden, T., Ludt, S., Gallacher, J. E. and Elwyn, G. 2011. What are effective strategies to communicate cardiovascular risk information to patients? A systematic review. Patient Education and Counseling 82(2), pp. 169-181. (10.1016/j.pec.2010.04.014)
- Waldron, C., Gallacher, J. E., van der Weijden, T., Newcombe, R. G. and Elwyn, G. 2010. The effect of different cardiovascular risk presentation formats on intentions, understanding and emotional affect: a randomised controlled trial using a web-based risk formatter (protocol). BMC Medical Informatics and Decision Making 10(1), article number: 41. (10.1186/1472-6947-10-41)
Conferences
- Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)
Thesis
- Waldron, C. 2011. Cardiovascular risk prediction: how useful are web-based tools and do risk representation formats matter?. PhD Thesis, Cardiff University.
Research
Research Interests
- Infections, Inflammation and Immunity
- Vascular Disease
- Sepsis
- Biomarkers
- Antimicrobial Stewardship
- Surgical Trials
- Medical Devices
I conduct evidence-based research testing the effectiveness of interventions with the aim of reducing antibiotic resistance. Also, improving the quality of evidence and innovation in surgery, medical devices and other complex interventions.
Grants
2023: NIHR Health Technology Assessment (HTA) programme - CLopidogrel, Aspirin and Rivaroxaban after revascularisation with angioplasTY (CLARITY), (Co-Applicant, CTR study lead) £2,575,967.
2023: NIHR Health Technology Assessment (HTA) programme - Platform randomised evaluation of clinical outcomes using novel technologies to optimise antimicrobial therapy (PROTECT), (Co-Applicant) £204,987.
2022: NIHR Health Technology Assessment (HTA) programme - Perineural Local Anaesthetic Catheter aftEr Major lowEr limb amputatioN Trial (PLACEMENT), (Co-Applicant, CTR study lead) £1,635,918.
2020: NIHR Efficacy and Mechanism Evaluation (EME) programme - MR-PRo-adrenomedullin (MR-proADM) and ImmunoXpert Evaluation of procalcitonin-guided antibiotic duration in Children with Infection for Stratification of Effectiveness (PRECISE) study, (Co-Applicant) £385,450.
2020: Health and Care Research Wales RfPPB programme - PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation - a collaboratiVE study (PERCEIVE), (Co-Applicant, CTR study lead) £229,225.
Biography
Honours and awards
- 2011: PhD (Medicine), Cardiff University.
- 2006: BSc (Hons) Psychology, University of Wales Institute, Cardiff.
Funded by Medical Research Council (Doctoral Training Grant).
Thesis: Cardiovascular Risk Prediction: How useful are web-based tools and do risk representation formats matter?
Professional memberships
Member of the UK Trial Managers' Network (UK TMN).
British Psychological Society - Graduate Member and Division of Health Psychology Member.
Academic positions
2020-present - Research Fellow / Senior Trial Manager, Centre for Trials Research, Cardiff University.
2012-2020 - Research Associate / Trial Manager, Centre for Trials Research, Cardiff University.
2016-2017 - Research Associate / Trial Coordinator (secondment), School of Social and Community Medicine, University of Bristol.
2011-2012 - Research Assistant / Assistant Trial Manager, South East Wales Trials Unit, Cardiff University.
Research themes
Specialisms
- Behaviour Change
- Infectious diseases
- Cardiovascular diseases
- Clinical Trials
- Vascular Conditions