Professor Karl Swann
I am interested in cell signalling and metabolism during animal fertilization and early embryo development. I use live cell imaging methods including those based on fluorescence and chemiluminescence.
Selected projects are:
1. The role and mechanism of action of PLCzeta in mammalian fertilization.
2. The use of PLCzeta in the diagnosis and treatment of male factor infertility in humans
3. The effect of Ca2+ oscillations upon egg activation and early development.
4. Lipid droplets and lipid metabolism in eggs and early embryos using CARS microscopy.