Dr Andrew Hollins

2022

• Engel, R. M. et al. 2022. Modeling colorectal cancer: A bio-resource of 50 patient-derived organoid lines. Journal of Gastroenterology and Hepatology 37(5), pp. 898-907. (10.1111/jgh.15818)

2020

• Badder, L. M. et al. 2020. 3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors. PLoS ONE 15(8), article number: e0235319. (10.1371/journal.pone.0235319)

2016

• Hollins, A. J. and Parry, L. 2016. Long-term culture of intestinal cell progenitors: an overview of their development, application, and associated technologies. Current Pathobiology Reports 4(4), pp. 209-219. (10.1007/s40139-016-0119-1)

2011

• Patani, R. et al. 2011. Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state. Nature Communications 2, article number: 214. (10.1038/ncomms1216)
• Hollins, A. J., Joy, S., Kelly, C. M., Battersby, A. A., Allen, N. D. and Rosser, A. E. 2011. Transplantation of differentiated human embryonic stem cells into a Huntington's Disease model: The challenges of generating neural cells suitable for replacement therapy in neurodegenerative disease. Cell Transplantation 20(4), pp. 563-564.

2009

• Benter, I. F., Benboubetra, M., Hollins, A. J., Yousif, M. H. M., Canatan, H. and Akhtar, S. 2009. Early inhibition of EGFR signaling prevents diabetes-induced up-regulation of multiple gene pathways in the mesenteric vasculature. Vascular Pharmacology 51(4), pp. 236-245. (10.1016/j.vph.2009.06.008)

2008

• Davies, V. J. et al. 2008. A missense mutation in the murine Opa3 gene models human Costeff syndrome. Brain 131(2), pp. 368-380. (10.1093/brain/awm333)

2007

• Davies, V. J. et al. 2007. Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function. Human Molecular Genetics 16(11), pp. 1307-1318. (10.1093/hmg/ddm079)
• Barar, J., Campbell, L., Hollins, A. J., Thomas, N. P., Smith, M. W., Morris, C. J. and Gumbleton, M. 2007. Cell selective glucocorticoid induction of caveolin-1 and caveolae in differentiating pulmonary alveolar epithelial cell cultures. Biochemical and Biophysical Research Communications 359(2), pp. 360-366. (10.1016/j.bbrc.2007.05.106)

2005

• Griffiths, S., Yousif, M. H., Benter, I. F., Hollins, A. J. and Akhtar, S. 2005. The effect of hyperglycaemia on EGFR signalling and its potential role in diabetes-induced vascular dysfunction [abstract]. Journal of Pharmacy and Pharmacology 57(S1), pp. S37-S37. (10.1211/002235705778248451)
• Omidi, Y., Hollins, A. J., Drayton, R. and Akhtar, S. 2005. Polypropylenimine dendrimer-induced gene expression changes: The effect of complexation with DNA, dendrimer generation and cell type. Journal of drug targeting 13(7), pp. 431-443. (10.1080/10611860500418881)

2004

• Hollins, A. J., Omidi, Y., Fox, S. P., Griffiths, S. and Akhtar, S. 2004. Polyethylenimine-mediated delivery of small interfering RNA targeting the epidermal growth factor receptor: a comparison of linear and branched polymer architecture [abstract]. Journal of Pharmacy and Pharmacology 56(S1), pp. 19-20. (10.1211/002235704777489375)
• Omidi, Y., Benboubetra, M., Hollins, A. J., Drayton, R. and Akhtar, S. 2004. Dendrimeric delivery systems for siRNA and gene therapy intrinsically alter gene expression in human epithelial cells [abstract]. Journal of Pharmacy and Pharmacology 56(S1), pp. 19-19., article number: 52. (10.1211/002235704777489375)
• Fox, S. P., Hollins, A. J., Sohail, M., Omidi, Y., Southern, E., Benboubetra, M. and Akhtar, S. 2004. The design and activity of small interfering RNA (siRNA) as a potential therapeutic agent for the down-regulation of the epidermal growth factor receptor (EGFR) [abstract]. Journal of Pharmacy and Pharmacology 56(S1), pp. 10-11. (10.1211/002235704777489375)
• Gilmore, I. R., Fox, S. P., Hollins, A. J., Muhammad, S. B. and Akhtar, S. 2004. The design and exogenous delivery of siRNA for post-transcriptional gene silencing. Journal of drug targeting 12(6), pp. 315-340. (10.1080/10611860400006257)

2003

• Omidi, Y., Hollins, A. J., Benboubetra, M., Drayton, R., Benter, I. F. and Akhtar, S. 2003. Toxicogenomics of non-viral vectors for gene therapy: A microarray study of lipofectin- and oligofectamine-induced gene expression changes in human epithelial cells. Journal of drug targeting 11(6), pp. 311-323. (10.1080/10611860310001636908)
• Campbell, L., Abulrob, A. G., Kandalaft, L., Plummer, S., Hollins, A. J., Gibbs, A. and Gumbleton, M. 2003. Constitutive expression of P-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures. Journal of Pharmacology and Experimental Therapeutics 304(1), pp. 441-452. (10.1124/jpet.102.042994)

2002

• Hollins, A. J., Campbell, L., Gumbleton, M. and Evans, D. J. R. 2002. Caveolin expression during chondrogenesis in the avian limb. Developmental Dynamics 225(2), pp. 205-211. (10.1002/dvdy.10143)

1999

• Campbell, L., Hollins, A. J., Al-Eid, A., Newman, G. R., Von Ruhland, C. J. and Gumbleton, M. 1999. Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures. Biochemical and Biophysical Research Communications 262(3), pp. 744-751. (10.1006/bbrc.1999.1280)