Hugo Creeth

2022

• Creeth, H. D. J. et al. 2022. Ultrarare coding variants and cognitive function in schizophrenia. JAMA Psychiatry 79(10), pp. 963-970. (10.1001/jamapsychiatry.2022.2289)

2021

• Harrison, D. J. et al. 2021. Placental endocrine insufficiency programs anxiety, deficits in cognition and atypical social behaviour in offspring. Human Molecular Genetics 30(19), pp. 1863-1880., article number: ddab154. (10.1093/hmg/ddab154)
• Rees, E. et al. 2021. Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations. Nature Communications 12, article number: 5353. (10.1038/s41467-021-25532-4)

2020

• Creeth, H. D. J. and John, R. M. 2020. The placental programming hypothesis: placental endocrine insufficiency and the co-occurrence of low birth weight and maternal mood disorders. Placenta 98, pp. 52-59. (10.1016/j.placenta.2020.03.011)
• Harrison, D. J. et al. 2020. Unified behavioral scoring for preclinical models. Frontiers in Neuroscience 14, article number: 313. (10.3389/fnins.2020.00313)

2018

• Tunster, S. J., Van de Pette, M., Creeth, H. D. J., Lefebvre, L. and John, R. M. 2018. Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome. Disease Models and Mechanisms 11, article number: dmm035832. (10.1242/dmm.035832)
• Tunster, S. J., Boque Sastre, R., McNamara, G., Hunter, S. M., Creeth, H. D. J. and John, R. M. 2018. Peg3 deficiency results in sexually dimorphic losses and gains in the normal repertoire of placental hormones. Frontiers in Cell and Developmental Biology 6, article number: 123. (10.3389/fcell.2018.00123)
• Creeth, H. D. J. et al. 2018. Maternal care boosted by paternal imprinting in mammals. PLoS Biology 16(7), article number: e2006599. (10.1371/journal.pbio.2006599)
• McNamara, G. I., Creeth, H. D. J., Harrison, D. J., Tansey, K. E., Andrews, R. M., Isles, A. R. and John, R. M. 2018. Loss of offspring Peg3 reduces neonatal ultrasonic vocalizations and increases maternal anxiety in wild-type mothers. Human Molecular Genetics 27(3), pp. 440-450. (10.1093/hmg/ddx412)

2016

• Tunster, S. J., McNamara, G., Creeth, H. and John, R. M. 2016. Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta. Developmental Biology 418(1), pp. 55-65. (10.1016/j.ydbio.2016.08.014)
• Janssen, A. B., Kertes, D. A., McNamara, G., Braithwaite, E. C., Creeth, H., Glover, V. I. and John, R. M. 2016. A role for the placenta in programming maternal mood and childhood behavioural disorders. Journal of Neuroendocrinology 28(8) (10.1111/jne.12373)
• Tunster, S. J., Creeth, H. and John, R. M. 2016. The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources. Developmental Biology 409(1), pp. 251-260. (10.1016/j.ydbio.2015.10.015)
• Creeth, H. 2016. Exploring a novel mechanism instructing maternal care and influencing offspring outcomes. PhD Thesis, Cardiff University.