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Dr Erik Mire

Research Fellow, Neuroscience & Mental Health Research Institute

Yr Ysgol Meddygaeth

Email
miree@cardiff.ac.uk
Campuses
Adeilad Hadyn Ellis, Heol Maendy, Caerdydd, CF24 4HQ
Users
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My main interest are nicely exposed in the following declaration from UNICEF:

«The first 1,000 days of life - the time spanning roughly between conception and one’s second birthday - is a unique period of opportunity when the foundations of optimum health, growth, and neurodevelopment across the lifespan are established. Yet, too frequently in developing countries, poverty and its attendant condition, malnutrition, weaken this foundation, leading to earlier mortality and significant morbidities such as poor health, and more insidiously, substantial loss of neurodevelopmental potential » 

I aim to understand how early life events, in particular related to diet, impact how our brain is shaped, with the idea that this will be crucial for its function later in life.

2018

2017

2015

2014

2012

2011

2007

Projects

Current projects investigate how maternal obesity impacts brain development with a focus on diet and lipid metabolism.

We use state of the art approaches in imaging (lightsheet microscopy and brain clearing) and embryology (in utero electroporation), as well as mouse genetics, FACS, lipidomics, organotypic brain slice culture to study the cellular and molecular processes altered by maternal obesity in the offspring's brain.

The ultimate goal is to provide much needed information on signaling pathways and critical periods to help design preventive/corrective strategies for neuropsychiatirc disorders.

Collaborators

Professor Valerie O'Donnell, Cardiff University

Professor Paola Borri, Cardiff University

Professor William Griffiths, Swansea University

Funding

Research in the lab is supported by :

Wellcome Trust / Cardiff University ISSF Cross Disciplinary Award

Academy of Medical Science's Springboard Award

The Hodge Centre for Neuropsyciatric Immunology

Proffiliau allanol

Delweddau

No results were found

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