Miss Ana Silva

Myfyriwr ymchwil, Psychological Medicine & Clinical Neurosciences, Yr Ysgol Meddygaeth

: silvaai@cardiff.ac.uk
: +44 29208 74000 Ext 20023

Mae'r cynnwys hwn ar gael yn Saesneg yn unig.

Traethawd ymchwil

Investigating the effects of copy number variants (CNVs conferring high risk for schizophrenia on brain structure and function using MRI

2024

Kopal, J. et al. 2024. Using rare genetic mutations to revisit structural brain asymmetry. Nature Communications 15(1), article number: 2639. (10.1038/s41467-024-46784-w)

2023

Kumar, K. et al. 2023. Subcortical brain alterations in carriers of genomic copy number variants. The American Journal of Psychiatry 180(9), pp. 685-698. (10.1176/appi.ajp.20220304)
Kopal, J. et al. 2023. Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence. Nature Human Behaviour 7, pp. 1001-1007. (10.1038/s41562-023-01541-9)
Moreau, C. A. et al. 2023. Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions. Brain 146(4), pp. 1686-1696. (10.1093/brain/awac315)
Moreau, C. A. et al. 2023. Genetic heterogeneity shapes brain connectivity in psychiatry. Biological Psychiatry 93(1), pp. 45-58. (10.1016/j.biopsych.2022.08.024)

2022

Willow, J., Silva, A. I., Taning, C. N. T., Smagghe, G. and Veromann, E. 2022. Towards dsRNA ‐integrated protection of medical Cannabis crops: considering human safety, recent‐ and developing RNAi methods, and research inroads. Pest Management Science (10.1002/ps.7323)
Silva, A. I. et al. 2022. Neuroimaging findings in neurodevelopmental copy number variants: identifying molecular pathways to convergent phenotypes. Biological Psychiatry 92(5), pp. 341-361. (10.1016/j.biopsych.2022.03.018)

2021

Silva, A. I. et al. 2021. Analysis of diffusion tensor imaging data from the UK Biobank confirms dosage effect of 15q11.2 copy number variation on white matter and shows association with cognition. Biological Psychiatry 90(5), pp. 307-316. (10.1016/j.biopsych.2021.02.969)
Modenato, C. et al. 2021. Effects of eight neuropsychiatric copy number variants on human brain structure. Translational Psychiatry 11(1), article number: 399. (10.1038/s41398-021-01490-9)
Sønderby, I. E., Hall, J., Owen, M., Van Den Bree, M., Linden, D., Silva, A. and Doherty, J. 2021. 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans. Translational Psychiatry 11, article number: 182. (10.1038/s41398-021-01213-0)

2019

Silva, A. I. et al. 2019. Reciprocal white matter changes associated with copy number variation at 15q11.2 BP1-BP2: A diffusion tensor imaging study. Biological Psychiatry 85(7), pp. 563-572. (10.1016/j.biopsych.2018.11.004)
Silva, A. R. R., Santos, C. and Ferreira, N. 2019. Multigenerational effects of carbendazim in daphnia magna: from a subcellular to a population level. Environmental Toxicology and Chemistry 38(2), pp. 412-422. (10.1002/etc.4307)
Silva, A. I. 2019. The effects of the 15q11.2 BP1-BP2

copy number variant on white matter microstructure. PhD Thesis, Cardiff University.

2018

Piggott, L. et al. 2018. Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through post-translational downregulation of c-FLIP. Clinical Cancer Research 24(10), pp. 2452-2463. (10.1158/1078-0432.CCR-17-1381)

2016

Wilkes, M. A. et al. 2016. Early careers on ecohydraulics: challenges, opportunities and future directions. Journal of Ecohydraulics 1(1-2), pp. 102-107. (10.1080/24705357.2016.1249423)