Learn about the work our research groups are doing and the people involved.
The Intestinal Cancer Research Group models colorectal cancer in the mouse and assesses pathway synergies and antagonisms in-vivo and validating therapeutic targets.
The Tumour Heterogeneity group is trying to understand why tumours which originate in a single tissue can have very different appearances in biology and behaviour.
The Targeting Metastasis group focuses on identifying novel therapeutic strategies to eliminate or modify the cancer cells responsible for the spread of tumours around the body.
The Leukaemic Stem Cells group focusses on understanding and therapeutically targeting leukaemic stem cells in acute myeloid leukaemia.
The Stem Cell Fate Dynamics group focuses on understanding the molecular mechanisms whereby tissue stem cells balance differentiation and self-renewal.
This research group focuses on the earliest stages of cancer in epithelial tissues.
This research group focuses on identifying how dietary components alter the behaviour of normal and cancerous stem cells.
The Skin Cancer Programme uses skin cancer stem cell models to find new ways to prevent, detect and develop novel therapies for all cancer types.
This research group investigates transcriptional regulation of cell plasticity in normal and transformed astrocytes.
The Blood Stem Cells and Leukaemia research group studies the regulation of human normal versus malignant blood development.
The Cancer and Cell Signalling research group investigates the requirement of cell signalling during homeostasis, to identify novel therapeutic targets and strategies for the treatment of cancer.
Our aim here is to improve our understanding of the role of cancer stem cells in a range of cancers, through world-leading research.