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Dr Amal Gadalla
Lecturer in Biomedical Sciences
- GadallaA1@cardiff.ac.uk
- +44 29206 88102
- Cochrane Building, Room 5th floor, Heath Park, Cardiff, CF14 4YU
- Available for postgraduate supervision
Overview
I am a Lecturer in Biomedical Sciences; I teach a wide range of biomedical sciences to medical and science students. I am passionate about supporting students to learn biomedical sciences in a way that is integrated into medical practice and cutting-edge research.
I endeavor to use my advanced skills in programming and online learning to create attractive materials to medical/biomedical students.
My area of interest is infectious diseases genomics, but my multidisciplinary education and work experience allow me to teach microbiology, immunology, epidemiology, research methods, statistical analysis, statistical modeling, and machine learning. I am also very enthusiastic to support and supervise undergraduate and postgraduate students.
Publication
2022
- Gadalla, A. et al. 2022. Antibiotic consumption and time to recovery from uncomplicated urinary tract infection: secondary analysis of observational data from a point-of-care test trial. British Journal of General Practice 72(725), pp. 882-890. (10.3399/BJGP.2022.0011)
- Al Mahrouqi, S. et al. 2022. Drug resistant Mycobacterium tuberculosis in Oman: resistance-conferring mutations and lineage diversity. PeerJ – the Journal of Life & Environmental Sciences 10, article number: e13645. (10.7717/peerj.13645)
- Al-Mahrouqi, S. et al. 2022. Dynamics of Mycobacterium tuberculosis Lineages in Oman, 2009 to 2018. Pathogens 11(5), article number: 541. (10.3390/pathogens11050541)
2021
- Gadalla, A. A. H. et al. 2021. Real-time PCR assays for detection and quantification of early P. falciparum gametocyte stages. Scientific Reports 11, article number: 19118. (10.1038/s41598-021-97456-4)
2020
- Awad, H. et al. 2020. Dynamics and within-host interaction of Theileria lestoquardi and T. ovis among naive sheep in Oman. Scientific Reports 10(1), article number: 19802. (10.1038/s41598-020-76844-2)
- Al-Rumhi, A. et al. 2020. Influx of diverse, drug resistant and transmissible Plasmodium falciparum into a malaria-free setting in Qatar. BMC Infectious Diseases 20(1), article number: 413. (10.1186/s12879-020-05111-6)
2019
- Gadalla, A. A. M. et al. 2019. Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms. Scientific Reports 9(1), article number: 19694. (10.1038/s41598-019-55523-x)
- Bakhiet, A. M. A. et al. 2019. Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan. Transactions of The Royal Society of Tropical Medicine and Hygiene 113(11), pp. 693-700. (10.1093/trstmh/trz059)
- Schneider, P., Babiker, H. A., Gadalla, A. A. H. and Reece, S. E. 2019. Evolutionary sex allocation theory explains sex ratios in natural Plasmodium falciparum infections. International Journal for Parasitology 49(8), pp. 601-604. (10.1016/j.ijpara.2019.04.001)
2018
- Abdelraheem, M. H. et al. 2018. Genetic diversity and transmissibility of imported Plasmodium vivax in Qatar and three countries of origin. Scientific Reports 8, article number: 8870. (10.1038/s41598-018-27229-z)
2016
- Gadalla, A. A. et al. 2016. Associations between season and gametocyte dynamics in chronic plasmodium falciparum infections. Plos One 11(11), article number: e0166699. (10.1371/journal.pone.0166699)
2015
- Schneider, P. et al. 2015. Quantification of female and male Plasmodium falciparum gametocytes by reverse transcriptase quantitative PCR. Molecular and Biochemical Parasitology 199(1-2), pp. 29-33. (10.1016/j.molbiopara.2015.03.006)
- Gadalla, N. B. et al. 2015. Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. Journal of Antimicrobial Chemotherapy 70(1), pp. 116-123. (10.1093/jac/dku358)
2013
- Babiker, H. A., Gadalla, A. A. and Ranford-Cartwright, L. C. 2013. The role of asymptomatic P. falciparum parasitaemia in the evolution of antimalarial drug resistance in areas of seasonal transmission. Drug Resistance Updates 16(1-2), pp. 1-9. (10.1016/j.drup.2013.02.001)
2011
- Gadalla, N. B. et al. 2011. Increased pfmdr1 copy number and sequence polymorphisms in lasmodium falciparum Isolates from Sudanese malaria patients treated with artemether-lumefantrine. Antimicrobial Agents and Chemotherapy 55(11), pp. 5408-5411. (10.1128/AAC.05102-11)
Articles
- Gadalla, A. et al. 2022. Antibiotic consumption and time to recovery from uncomplicated urinary tract infection: secondary analysis of observational data from a point-of-care test trial. British Journal of General Practice 72(725), pp. 882-890. (10.3399/BJGP.2022.0011)
- Al Mahrouqi, S. et al. 2022. Drug resistant Mycobacterium tuberculosis in Oman: resistance-conferring mutations and lineage diversity. PeerJ – the Journal of Life & Environmental Sciences 10, article number: e13645. (10.7717/peerj.13645)
- Al-Mahrouqi, S. et al. 2022. Dynamics of Mycobacterium tuberculosis Lineages in Oman, 2009 to 2018. Pathogens 11(5), article number: 541. (10.3390/pathogens11050541)
- Gadalla, A. A. H. et al. 2021. Real-time PCR assays for detection and quantification of early P. falciparum gametocyte stages. Scientific Reports 11, article number: 19118. (10.1038/s41598-021-97456-4)
- Awad, H. et al. 2020. Dynamics and within-host interaction of Theileria lestoquardi and T. ovis among naive sheep in Oman. Scientific Reports 10(1), article number: 19802. (10.1038/s41598-020-76844-2)
- Al-Rumhi, A. et al. 2020. Influx of diverse, drug resistant and transmissible Plasmodium falciparum into a malaria-free setting in Qatar. BMC Infectious Diseases 20(1), article number: 413. (10.1186/s12879-020-05111-6)
- Gadalla, A. A. M. et al. 2019. Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms. Scientific Reports 9(1), article number: 19694. (10.1038/s41598-019-55523-x)
- Bakhiet, A. M. A. et al. 2019. Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan. Transactions of The Royal Society of Tropical Medicine and Hygiene 113(11), pp. 693-700. (10.1093/trstmh/trz059)
- Schneider, P., Babiker, H. A., Gadalla, A. A. H. and Reece, S. E. 2019. Evolutionary sex allocation theory explains sex ratios in natural Plasmodium falciparum infections. International Journal for Parasitology 49(8), pp. 601-604. (10.1016/j.ijpara.2019.04.001)
- Abdelraheem, M. H. et al. 2018. Genetic diversity and transmissibility of imported Plasmodium vivax in Qatar and three countries of origin. Scientific Reports 8, article number: 8870. (10.1038/s41598-018-27229-z)
- Gadalla, A. A. et al. 2016. Associations between season and gametocyte dynamics in chronic plasmodium falciparum infections. Plos One 11(11), article number: e0166699. (10.1371/journal.pone.0166699)
- Schneider, P. et al. 2015. Quantification of female and male Plasmodium falciparum gametocytes by reverse transcriptase quantitative PCR. Molecular and Biochemical Parasitology 199(1-2), pp. 29-33. (10.1016/j.molbiopara.2015.03.006)
- Gadalla, N. B. et al. 2015. Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. Journal of Antimicrobial Chemotherapy 70(1), pp. 116-123. (10.1093/jac/dku358)
- Babiker, H. A., Gadalla, A. A. and Ranford-Cartwright, L. C. 2013. The role of asymptomatic P. falciparum parasitaemia in the evolution of antimalarial drug resistance in areas of seasonal transmission. Drug Resistance Updates 16(1-2), pp. 1-9. (10.1016/j.drup.2013.02.001)
- Gadalla, N. B. et al. 2011. Increased pfmdr1 copy number and sequence polymorphisms in lasmodium falciparum Isolates from Sudanese malaria patients treated with artemether-lumefantrine. Antimicrobial Agents and Chemotherapy 55(11), pp. 5408-5411. (10.1128/AAC.05102-11)
- Bakhiet, A. M. A. et al. 2019. Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan. Transactions of The Royal Society of Tropical Medicine and Hygiene 113(11), pp. 693-700. (10.1093/trstmh/trz059)
- Schneider, P., Babiker, H. A., Gadalla, A. A. H. and Reece, S. E. 2019. Evolutionary sex allocation theory explains sex ratios in natural Plasmodium falciparum infections. International Journal for Parasitology 49(8), pp. 601-604. (10.1016/j.ijpara.2019.04.001)
- Abdelraheem, M. H. et al. 2018. Genetic diversity and transmissibility of imported Plasmodium vivax in Qatar and three countries of origin. Scientific Reports 8, article number: 8870. (10.1038/s41598-018-27229-z)
Research
I focus my research to investigate within-host dynamics and diagnosis of infectious diseases using bioinformatics, statistical modelling, and machine learning tools. I also have a particular research interest in drug resistance.
Current Projects:
- Evaluation of DNA sequencing approaches in identification of bacterial microbiome in urine. Status: ongoing and transferable to a new institute without negotiations. Role: Principal Investigator. Status: Ongoing
- What are the effects of established glucocorticoid therapy on the risk of adverse COVID-19 outcomes? Role: Co-Investigator. Status: Ongoing
Previous Projects:
- Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms. Status: completed.
- Molecular methods for detection and monitoring of imported malaria in Oman. Status: completed.
- Theileria parasite in Oman, molecular biology and disease. Status: completed.
- Identification of Plasmodium falciparum early gametocyte-specific expression in natural infections. In collaboration with the University of Edinburgh, Edinburgh, UK, Queensland Institute of Medical Research, Queensland, Australia, and Istituto Superiore di Sanità, Italy. Status: completed.
- Validation of the use of isotope-based molecular techniques in malaria control. Status: completed.
- Molecular genetics of Plasmodium falciparum isolates in Sudan: Gametocytaemia and drug resistance markers. Status: completed.
Teaching
Teaching and assessment:
- Numeracy Lead September 2022 – current: a vertically integrated module delivered across the year 1 to year 5 medical students to support their understanding of numbers, equations, prescription calculations and research data analysis. The module also supports intercalated program students and postgraduates in the School of Medicine, Cardiff University, UK.
- Cell Signalling and 2nd Messenger Tutorial Lead September 2022 – current: face-to-face and online tutorials as part of ME1101 module. Students: Year 1 medical students.
- Case Based Learning (ME1106 and ME2100) facilitation January 2022 – current: year 1 and year 2 medical students.
- Clinical Epidemiology Intercalated BSc degree (ME3064) 2018 – current: for Medicine undergraduate students, Cardiff University. Teaching subject “The use of ’omics in infectious diseases diagnosis and research”, then assess students’ projects and presentations.
- Platform for Clinical Sciences module (ME1101) 2018 – current: Delivery of various biomedical sciences lectures tutorials within the: cell structure and function, enzymes, cell signalling, evidence-based medicine, applied immunology, molecular biology, haematology and microbiology. Students: year 1 and 2 medical students.
Biography
Educations
- 2015 – PhD Biochemistry and Molecular Biology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman. Thesis title: "Influence of season, drug resistance, genetic complexity and anti-malarials on persistence and transmission of the malaria parasite Plasmodium falciparum"
- 2008 – MSc Biomedical Sciences (Immunology), Sudan Academy for Sciences, Khartoum, Sudan. Thesis title: "IgG profile against MSP3 antigen in asymptomatic carriers of Plasmodium falciparum in Eastern Sudan"
- 2004 – BSc (1st Class Honours) Medical Laboratory Sciences (major Microbiology), Faculty of Medical Laboratory Sciences, University of Gezira, Sudan.
Career overview
- 2022 – current: Lecturer in Biomedical Sciences, Centre for Medical Education, School of Medicine, Cardiff University.
- 2017 – 2021: Research Associate, Division of Population Medicine, School of Medicine, Cardiff University.
- 2017: Technical expert, International Atomic Energy Agency.
- 2014 – 2015: Part-time Research fellow, Biochemistry and Molecular Biology, Sultan Qaboos University, Muscat, Oman.
- 2004 – 2010: Part-time Research assistant then promoted to Full-Time Researcher, Tropical Medicine Research Institute, National Centre for Research, Khartoum, Sudan.
Honours and awards
- 2022 to 2023 – Cardiff University Education Fellowship working towards Fellow status of the High Education Academy, UK.
- 2019 – Wellcome Trust ISSF Population award.
- 2017 – Cardiff University Research Associate post initiation fund.
- 2017 – Jamal Elnefeidi Award for best research in malaria, Sudan.
- 2016 – American Society of Tropical Medicine and Hygiene (ASTMH) Travel Award. Prestigious one in life-time award.
- 2016 – European Molecular Biology Laboratory (EMBL), Advanced Training Centre Corporate Partnership Programme (CPP) Fellowship Travel Award.
- 2016 – British Society of Parasitology Spring Meeting Travel Award.
- 2013 – 6th Multilateral Initiative on Malaria Pan-African Malaria Conference Travel Award.
- 2012 – Training fellowship award. International Atomic Energy Agency (IAEA).
- 2010 – PhD scholarship, Sultan Qaboos University, Muscat, Oman.
- 2007 – MSc scholarship, Sudan Academy for Sciences, Khartoum, Sudan.
- 2003 – Academic Excellence Award, University of Gezira, Sudan
Professional memberships
- International Society of Infectious Diseases, member
- SM Tropical Medicine Journal, member of the Editorial Board
- British Society of Parasitology, member
Committees and reviewing
Journal reviewer, PloS ONE
Engagement
Media engagment
- Radio broadcast: 9-series (Arabic language) discussions about Covid-19 outbreak to increase public awareness about Covid-19 outbreak. Initiator and presenter: Dr Noon Abdelgafar, Leicester, UK. Participants: A group of international medical scientists and clinicians working and living in UK, France, USA, United Arabic Emirates and Saudi Arabia who are originally from Sudan alongside Covid-19 frontline clinicians and scientist working in Sudan.
- Malaria Season: Q&A With Amal Gadalla. 2017. Global Health NOW. Johns Hopkins Bloomberg School of Public Health.https://www.globalhealthnow.org/2017-01/malaria-season-qa-amal-gadalla?utm_source=Global+Health+NOW+Main+List&utm_campaign=3b9bce0ed9-EMAIL_CAMPAIGN_2017_01_04&utm_medium=email&utm_term=0_8d0d062dbd-3b9bce0ed9-860291
- Radio interview highlighting the publication on seasonal gametocytes dynamic and its relevance to malaria epidemics in Sudan, 22 January 2017, Fakhr Beladi Program (Pride of My Country), Fakhr Beladi Broadcast, Khartoum, Sudan.