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Dr Alex White

Dr Alex White

Lecturer and Examinations Officer

School of Pharmacy and Pharmaceutical Sciences

Email:
whiteaw@cardiff.ac.uk
Telephone:
+44 (0)29 2087 6308
Fax:
+44 (0)29 2087 4149

Co-inventor of rucaparib, a PARP inhibitor licenced in the UK/EU in 2018 for the treatment of advanced ovarian cancer. Currently developing methods for the large scale extraction of bio-active natural products from bulk plant material. Particularly of interest is the development of natural product lead compounds as clinically useful chemotherapeutic agents.

Career profile 

Graduated from the University of Newcastle upon Tyne and awarded a PhD in anti-cancer drug design from the same University. Held a faculty research position at the Arizona State University Cancer Research Institute under Professor Bob Pettit studying the anti-cancer constituents of marine organisms. Returned to the UK as a research associate at the Northern Institute of Cancer Research (1998-2000) and joined the staff of the School of Pharmacy and Pharmaceutical Sciences in 2000.

2018

2013

2012

2011

2010

2008

2004

2002

2000

Convenor of undergraduate examinations

  • PH1121  Molecule to patient
  • PH1122  The role of the pharmacist in professional practice
  • PH1123  Structure and function of cells and microbes
  • PH1124  Human body systems
  • PH1125  Chemical and biological properties of drug molecules
  • PH2110  Clinical & professional pharmacy
  • PH2112  Principles of drug design
  • PH2113  Diseases and drugs I
  • PH3101  Optimisation of drug design
  • PH3110  Optimisation of pharmaceutical care
  • PH3202  Research methodology
  • PH4116  Pharmacy research or scholarship project
  • PH4117  Pharmaceutical sciences, pharmacy practice and the population
  • PH4118  Pharmaceutical sciences, pharmacy practice and the patient

Natural Product Research and the design and synthesis of novel anti-cancer agents, especially using lead compounds from natural sources. We have been investigating natural products from Welsh marine organisms and have identified anti-cancer and anti-bacterial activity in extracts from Welsh sponges. Currently involved in isolation and characterisation of discrete biologically active molecules from large scale plant sources.