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 Timothy Pickles

Timothy Pickles

NIHR Doctoral Fellow

Email
pickleste@cardiff.ac.uk
Telephone
+44 (0)29 2068 7259
Campuses
Room 510, 5th floor, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
Comment
Media commentator

Overview

Research Themes

I work in the Centre for Trials Research (CTR) at Cardiff University. I was granted an NIHR Doctoral Fellowship in 2019 and am working on Psychometrics, patient reported outcome measures (PROMs), Rasch measurement theory and computer adaptive test in the field of Rheumatoid Arthritis.

I have previously held posts in the Cardiff Regional Experimental Arthritis Treatment and Evaluation (CREATE) Centre and had a secondment in the School of Dentistry, which as well as research, involved teaching statistics and SPSS to BDS students, and providing statistical support to MOrth and PhD students.

Until 2019, my work in CTR principally involved being the statistician on multiple and differing clinical trials, across many varied disciplines. I have developed an interest in diabetes, urinary tract infections, rheumatology and skin conditions, as well as dental caries from my previous work in the School of Dentistry. The interventions I have focussed on are behaviour change counselling, shared decision making tools and devices/aids for appropriate antibiotic prescribing.

In my role within the CREATE centre, I was researching the use of early phase clinical trial methodology in the field of rheumatology. I had already begun looking into techniques to explore the psychometric properties of various Quality of Life Instruments, and I was fortunate to spend my MSc dissertation learning about, and undertaking, Rasch analyses, which is a continuing research theme.

I have also undertaken meta-analyses and epidemiological research, and advised PhD students and relevant staff members. I am the statistical lead for CTR Standard Operating Procedures.

Following a succesful application, I joined the 2019 cohort of the GW4 Crucible on Digital Innovation.

I hold a BSc (Hons) Natural Sciences from the University of Bath and a MSc (distinction) in Operational Research and Appiled Statistics from Cardiff University.

Further links:

SOCRATES study: https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/socrates

Blog: http://blogs.cardiff.ac.uk/centre-for-trials-research/nihr-doctoral-fellowship-interview-with-tim-pickles/

publons: https://publons.com/author/1193132/timothy-pickles#profile

RSS StatsLife:

https://www.statslife.org.uk/members-area/member-news/sections-and-local-group-meeting-reports/3027-primary-healthcare-special-interest-group-meeting-internal-pilot-studies-and-early-phase-designs

https://www.statslife.org.uk/members-area/member-news/sections-and-local-group-meeting-reports/2412-primary-healthcare-special-interest-group-meeting-proms-in-health-economics

https://www.statslife.org.uk/members-area/sections-and-local-group-meeting-reports/4075-medical-section-meeting-on-multiple-imputation

Biography

Career Profile

2009 - 2014: Research Assistant, South East Wales Trials Unit and School of Dentistry, Cardiff University

2014 - 2019: Research Associate, Centre for Trials Research and Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre

2019 - present: NIHR Doctoral Fellow, Centre for Trials Research

Education and Qualifications

2009: 1st Class BSc (Hons) Natural Sciences with Industrial Placement, University of Bath

2014: MSc (Distinction) Operational Research and Applied Statistics, Cardiff University

Teaching Profile

BDS Dental Public Health Statistics Lectures and SPSS Sessions

Honours and awards

GradStat, Royal Statistical Society, 2016

Professional memberships

Fellow of the Royal Statistical Society

Academic positions

Career Profile

2009 - 2014: Research Assistant, South East Wales Trials Unit and School of Dentistry, Cardiff University

2014 - 2019: Research Associate, Centre for Trials Research and Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre

2019 - present: NIHR Doctoral Fellow, Centre for Trials Research

Speaking engagements

Pickles T, Christensen R, Tam L-S, Simon LS, Choy EH. Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials. Poster Session Presented at: ITCMC 2019. 5th International Clinical Trials Methodology Conference 2019; Oct 7-9, Brighton, UK.

Pickles T, Playle R, Hood K, Gillard J. Rasch analysis of the PedsQLTM 3.0 Diabetes Module. Paper presented at: ISOQOL 2014. Proceedings of the 21st ISOQOL Annual conference; 2014 Oct 15-18; Berlin, Germany. Qual Life Res 2014;23(Suppl1):304.4.

Pickles T, Channon S, Gregory J, Lowes L. Development of the social activities and independence questionnaire in paediatric diabetes as part of the DECIDE randomised controlled trial. Poster Session presented at: ISOQOL 2014. Proceedings of the 21st ISOQOL Annual conference; 2014 Oct 15-18; Berlin, Germany. Qual Life Res 2014;23(Suppl1):2110.

Pickles T, Playle R, Hood K, Gillard J, Robling M. Rasch analysis of the PedsQLTM 3.0 Diabetes Module. Paper presented at: CTMC 2013. Proceedings of the 2nd Clinical Trial Methodology Conference; 2013 Nov 18-19; Edinburgh, UK. Trials 2013;13(Suppl1):O40.

Pickles T, Butler CC, Waldron CA, Thomas-Jones E, Hood K, O’Brien K, Hay AD. Presentation, Management and Outcomes of Preschool Children with UTI Presenting in UK Primary Care. Paper presented at: GRIN 2013. Proceedings of the 15th General Practice Research Infections Network Conference; 2013 Oct 4-5; Nice, France.

Pickles T, Blewitt N, Chestnutt IG. Determinants of Recall Intervals in Children. Poster Session Presented at: BSODR 2013. 60th Annual Scientific Meeting and Exhibition of the British Society of oral and Dental Research; 2013 Sep 9-11, Bath, UK.

Pickles T, Gillard J, Hood K, Playle R. Rasch analysis of the PedsQLTM 3.0 Diabetes Module. Paper presented at: YSM 2013. Proceedings of the 39th Young Statisticians’ Meeting; 2013 Jul 4-5; Imperial College London, UK.

Pickles T, Murangwa MY, Hood K, Butler CC. The Use of Composite Outcomes in Behaviour Change. Paper presented at: YSM 2012. Proceedings of the 38th Young Statisticians’ Meeting; 2012 Apr 2-3; Queen’s College, Cambridge, UK.

Pickles T, Gregory JW, Robling R. Cluster Randomised Controlled Trial of a Psychosocial Behavioural Change Intervention on children with type-1 Diabetes: Analysis of Baseline Questionnaire Score Data. Paper presented at: YSM 2010. Proceedings of the 36th Young Statisticians’ Meeting; 2010 Mar 30-31; University of Liverpool, UK.

Publications

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2012

2011

2010

Supervision