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Dr Ian Brewis

Dr Ian Brewis

Senior Lecturer

School of Medicine

Email
brewisia@cardiff.ac.uk
Telephone
+44 (0)29 2068 8648
Campuses
UG11, Henry Wellcome Building for Biomedical Research, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN

Overview

My main role is as Central Biotechnology Services (CBS) Operational Director (0.6 full-time equivalent, FTE). I also have wider research infrastructure management responsibilties (0.2FTE) and a range of teaching commitments (0.2FTE).

I have been CBS Operational Director since Dec 2011. CBS (www.cardiff.ac.uk/central-biotechnology-services) is an ISO 9001:2015 certified and Good Clinical Laboratory Practice (GCLP) accredited Cardiff University Technology Facility. Based in the College of Biomedical and Life Sciences it has a remit across the entire College and is part of the Clinical Innovation Partnership between Cardiff and Vale University Health Board and Cardiff University. CBS provides gene expression and bioinformatics, proteins and diagnostics and cell analysis/imaging platforms, services, training and expertise to local researchers and external organisations. CBS also offers opportunities for hosting companies and can provide laboratory facilities, technological support, academic consultancy and access to a wide range of other university resources. Options for contract research and managed services are backed up by a proven track record of working with not-for-profit organisations, start-ups, SMEs and corporates. Please contact us at cbsadmin@cardiff.ac.uk and you can follow us on Twitter @CentralBioServ.

I am the School of Medicine Research Infrastrucuture Oversight Group (RIOG) Lead (since Apr 2022) and have several other research infrastruture management responsibilities at School and College level. Beyond Cardiff I am the Chair of the GW4 Alliance Technical Infrastructure and Knowledge (TIK) Working Group (Chair since Jun 2021 and a Founder Member since 2019). I am a Core Technologies for Life Sciences (CTLS) Executive Council Member (since 2017), Training Working Group Member and the Shadowing and Staff Exchange Focus Group Lead.

I have a varied teaching portfolio at both undergraduate and postgraduate levels which includes being the Lead for the MSc Bioinformatics Protein Biology and Omics module. I am also the School of Medicine C21 Divisional Teaching Lead for Clinical Innovation and the Postgraduate Research (PGR) Representative for Clinical Innovation. Previously I was the MSc Medical Research and Innovation Programme Director (2016-2017). Before that I was the MSc Bioinformatics Programme Director (2011-2016) and my close involvement with the Programme goes back to its establishment in 2004. I was also the Bioinformatics and Biostatistics Committee Teaching and Training Lead (2011-2016). 

I have experience as an External Examiner for five Masters Programmes at three Russell Group institutions: the University of Liverpool MRes and MSc in Advanced BIological Sciences (2016-2020); Queen Mary University of London MSc Bioinformatics Programme (2015-2019) and the University of York MSc Bioscience Technology (2012-2016) and MSc Post Genomic Biology (2014-2016) Programmes. From a research perspective I have served as an External Examiner for 13 PhD theses and 2 MRes theses. Formerly, and in my own time, I was also an Associate Lecturer at the Open University (2010-2017).

I was recruited to Cardiff in 2003 as part of the newly formed and Welsh Government funded Biostatistics and Bioinformatics Unit (BBU). A significant part of my recruitment tasked me to achieve funding, establish and lead a new Proteomics Facility. This was successful and, as CBS Proteomics Facility Academic Lead, I was responsible for a wide range of projects in extended collaborations with many Cardiff researchers and external clients. One major external contract was with Ovasort Ltd, who were primarily interested in sperm-based sex-selection in livestock, and I was the Scientific Director (2005-2009). 

The CBS Proteomics Facility was discontinued in 2014 and proteomics work is now outsourced to the University of Bristol as part of the GW4 Alliance. Please continue to contact me for proteomics advice and to facilitate collaborations and/or the provision of proteomics services.

My research has mainly involved the proteomic and functional characterisation of mammalian sperm cells at fertilization and this was conducted in close collaboration with Dr Bart Gadella at Utrecht University, The Netherlands for many years. My preferred career direction has resulted in my own research being a minor activity in Cardiff and I am no longer independently research active. My main association with the field now is as an Associate Editor for the journal Reproduction (2013-2023) and formerly I was also an Associate Editor for Molecular Human Reproduction (2012-2015). 

Before Cardiff I was a Senior Research Fellow at the University of Birmingham and Birmingham NHS Assisted Conception Unit (2000-2003) and a Postdoctoral Research Associate at the University of Sheffield (1993-2000). My research primarily focused on studying molecular aspects of sperm function but these varied roles also included a wide range of other research projects in reproduction and several years working on commercial projects (and in particular a male fertility test and a study using human stem cell technologies).

My PhD (1994) on the biochemistry of mammalian glycolipid anchors was conducted as a Research Assistant at the University of Leeds and also involved spending extended time with collaborators at the University of Dundee. Prior to this I was a Research Assistant at the University of York (1989-1990) where I investigated the biochemistry of the Fallopian tube in collaboration with colleagues at Hammersmith Hospital. Lastly I also studied for my first degree at the University of York and graduated in 1989 with a BSc (Hons) in Biology (Cell Biology and Biochemistry)

Biography

See the Overview Section

Publications

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Teaching

See the Overview Section

Supervision

See the Overview Section

Past projects

Engagement

See the Overview Section