Research
Research interests
I started my PhD with the CCMRC in October 2014 to work on a project entitled “Functional Role of Epithelial Protein Lost in Neoplasm (EPLIN) in Prostate Cancer Metastasis”. I graduated from Cardiff School of Biosciences in 2011 with a BSc in Biochemistry where I carried out my first research project and was introduced to basic techniques in molecular biology. Since undergrad, I worked in Industry for 2.5 years for an immunoassay development company and also spent 8 months at Swansea University where I further developed my research skills in molecular biology/genetics. I am looking forward to building confidence in this area of cancer research, specifically looking at EPLIN and how it’s implicated in cancer progression. I hope to make a genuine contribution to this area of science.
Supervisors
Publications
2022
- Collins, R. et al. 2022. Comparative analysis of small-molecule limk1/2 inhibitors: chemical synthesis, biochemistry, and cellular activity. Journal of Medicinal Chemistry (10.1021/acs.jmedchem.2c00751)
2019
- Sanders, A. et al. 2019. Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination. Oncotarget 10(59), pp. 6362-6377. (10.18632/oncotarget.27279)
2018
- Collins, R., Morgan, L., Owen, S., Ruge, F., Jiang, W. and Sanders, A. 2018. Mechanistic insights of epithelial protein lost in neoplasm in prostate cancer metastasis. International Journal of Cancer 143(10), pp. 2537-2550. (10.1002/ijc.31786)
2017
- Collins, R. J. 2017. Functional role of Epithelial Protein Lost in Neoplasm (EPLIN) in prostate cancer metastasis. PhD Thesis, Cardiff University.
2015
- Collins, R. J., Jiang, W. G., Hargest, R., Mason, M. D. and Sanders, A. J. 2015. EPLIN: a fundamental actin regulator in cancer metastasis?. Cancer and Metastasis Reviews 34(4), pp. 753-764. (10.1007/s10555-015-9595-8)