I have a long-standing interest in cancer metastasis and from 1987, my main research interest has been on the molecular and cellular basis of cancer invasion and metastasis and therapeutic aspects of targeting cancer metastasis. I have been particularly interested in the bone, peritoneal and brain metastasis from primary tumours including breast, prostate, lung, GI cancers. My research has been conducted in Cardiff's School of Medicine and I have collaborated widely with colleagues in the UK, China, Europe, North America and Asia.
Education and qualifications:
- 1995, MD research degree, University of Wales College of Medicine
- 1984, Primary medical degree (MB, BCh) in Clinical Medicine, Peking University Health Science Centre (Previously Beijing Medical University)
Career overview:
- 2014 - present: Dean of International, Cardiff University
- 2012 - present: Director of Cardiff China Medical Research Collaborative
- 2012 - present: Quality and Safety Improvement Faculty, National Health Service/UHB, National Health Service
- 2012 - present: Academic Director for International Relations, Cardiff University
- 2004 - present: Professor of Surgery and Tumour Biology, Cardiff University School of Medicine
- 2003 - 2004: Reader, University of Wales College of Medicine
- 1997 - 2003: Senior Lecturer, University of Wales College of Medicine
- 1996 - 1997: Senior Fellow, University of Wales College of Medicine
- 1989 - 1996: Research Fellow, University of Wales College of Medicine (currently Cardiff University's School of Medicine)
- 1987 - 1989: Chief Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing
- 1984 - 1987: Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing
Honours and awards
- Fellow of the Royal Society of Biology
- Fellow of the Royal Society of Medicine
- Honorary professorship at Peking University
- Honorary professorship at Capital Medical University
- Honorary professorship at Inner Mongolia University
- Honorary professorship at QingDao University
- International consultant for Beijing Lung Cancer Centre
Recent awards include:
- Member of the Most Excellent Order of the British Empire
- Marquis Who's Who as Prominent Cancer Researcher
- Outstanding Achievement Award, 19th World Congress of Oncology, Athens, Greece, October 2014
- Super Professor in America's Academic Row, June 2015
Professional memberships
- Member of the American Association for Cancer Research (AACR)
- Member of the British Association for Cancer Research (BACR)
- Member of the European Association for Cancer Research (EACR)
Academic positions
- 2014 - present: Dean of International, Cardiff University
- 2012 - present: Director of Cardiff China Medical Research Collaborative
- 2012 - present: Quality and Safety Improvement Faculty, National Health Service/UHB, National Health Service
- 2012 - present: Academic Director for International Relations, Cardiff University
- 2004 - present: Professor of Surgery and Tumour Biology, Cardiff University School of Medicine
- 2003 - 2004: Reader, University of Wales College of Medicine
- 1997 - 2003: Senior Lecturer, University of Wales College of Medicine
- 1996 - 1997: Senior Fellow, University of Wales College of Medicine
- 1989 - 1996: Research Fellow, University of Wales College of Medicine (currently Cardiff University's School of Medicine)
- 1987 - 1989: Chief Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing
- 1984 - 1987: Surgical Resident, Department of General Surgery, Peking UniversityFirst Hospital, Beijing
Speaking engagements
Recent speaking engagements include:
- 2017: International Gastic Cancer Conference
- 2016: Gordon Conference, Gerona, Spain
- 2016: British Society of Pharmacology
- 2016: GOC 2016, Prague
- 2016: 12th International Conference on Collateral Disease (Oncology Forum), Shanghai, China
- 2015: 11th International Conference on Collateral Disease, Shijiazhuang, China
- 2014: Peking University Postgraudate Society
- 2014: 19th World Congress on Advances in Oncology, Athens
- 2014: 9th International Conference of Anticancer Research, Sithonia
- 2013: Phoenix TV, Chinese Medicine in cancer therapies
- 2013: BBC report on new medicine in cancer treatment
Committees and reviewing
- 2014 - present: Member of the University International Board
Other academic activities:
Editorship:
- Editor-in-Chief: World Journal of Oncology
- Editor-in-Chief: Cancer Metastasis, Biology and Treatment http://www.springer.com/series/5761
- Editor-in-Chief: Journal of Molecular and Genetic Medicine http://www.omicsonline.com/open-access/molecular-genetic-medicine.php
Editorial Board membership includes:
- Member of the editorial board of the International Journal of Molecular Medicine, from 1999
- Advisory Board Member, ‘Advances in Therapy’, from 2008
- Editorial Board Member, ‘Current Oncology’, from 2008
- Editorial Board Member, ‘Journal of Surgical Oncology’, from 2008
- Editorial Board Member, ‘Current Signal Transduction Therapy’, from 2009
- Editorial Board Member, ‘World Journal of Gastroenterology’, from 2009
- Editorial Board Member, ‘Experimental and Therapeutic Medicine’, from 2009
- Editorial Board Member, ‘World Journal of Clinical Oncology’, From 2010
- Editorial Board Member, ‘World Journal of Oncology’, From 2010
- Editorial Board Member, ‘Chinese Journal of Cancer Research’, From 2010
- Editorial Board Member, ‘Current Cancer Therapy Reviews’, From 2010
- Editorial Board Member, ‘International Journal of Oncology'', from 2011
- Editorial Board Member, ‘Translational Medicine: Current Research'', from 2011
- Editorial Board Member, ‘Translational Gastrointestinal Cancer'', from 2011
- Editorial Board Member, ‘Biomedical Reports'', from 2012
- Editorial Board Member, ‘World Journal of Medical Genetics (WJMG)'', from 2012
- Academic consultant, 'Antitumour Pharmacy', from 2012
- Editorial Board Member: 'Journal of Cancer Research and Therapy', from 2012
- Editorial Board Member: 'Angiology', from 2012
- Editorial Board Member: 'AO Translational Research', from 2013
- Editorial Board Member: 'Chinese Journal of Biology', from 2013
- Editorial Board Member: 'Academic Journal of Capital Medical University', from 2013
- Editorial Board Member: 'Cancer Genomics and Proteomics', from 2014
- Editorial Board Member: 'Insight of Medical Physics', from 2015
- Editorial Board Member: 'Cancer Translational Medicine', from 2015
- Editorial Board Member: 'Biochemical and Biophysical Acta (BBA) Clinical'', from 2015
- Editorial Board Member: 'Cancer Hypothesis', from 2016
Books published
- ‘Cancer Metastasis, molecular and cellular basis and clinical intervention’, Editors Wen G Jiang and Robert E Mansel, Kluwer Academic Publishers, 2000 (ISBN 0-7923-6395-7). (http://www.springer.com/gb/book/9780792363958)
- ‘Growth Factors and their receptors in cancer metastasis’, Editors Wen G Jiang, Toshikazu Nakamura and Kunio Matsumoto, Kluwer Academic Publishers, 2001 (ISBN 0-7923-7141-0) (http://www.springer.com/gb/book/9780792371410)
- ‘Breast Cancer Metastasis’, Editors Robert E Mansel, Oystein Fodstad and Wen G Jiang, Spinger Publishers, 2007, ISBN: 978-1-4020-5866-0. (http://www.springer.com/gb/book/9781402058660)
- 'Electric Cell-Substrate Sensing in the investigation of cancer and cancer metastasis'. Wen G Jiang. Springer Publishers, 2012. ISBN 978-94-007-4926-9 (http://www.springer.com/biomed/cancer/book/978-94-007-4926-9)
- 'Tight junctions in cancer metastasis'. TA Martin and WG Jiang. Springer Publishers, March 2013 (ISBN 978-94-007-6027-1). (http://www.springer.com/gb/book/9789400760271)
2020
- Sun, Z.et al. 2020. Increased expression of Gremlin1 promotes proliferation and epithelial mesenchymal transition in gastric cancer cells and correlates with poor prognosis of patients with gastric cancer. Cancer Genomics and Proteomics 17(1), pp. 49-60. (10.21873/cgp.20167)
- Sun, Z.et al. 2020. Deregulated bone morphogenetic proteins and their receptors are associated with disease progression of gastric cancer. Computational and Structural Biotechnology Journal 18 (10.1016/j.csbj.2019.12.014)
2019
- Liu, J.et al. 2019. HOXB2 is a putative tumour promotor in human bladder cancer. Anticancer Research 39(12), pp. 6915-6921. (10.21873/anticanres.13912)
- Liu, J.et al. 2019. Increased expression of Psoriasin is correlated with poor prognosis of bladder transitional cell carcinoma by promoting invasion and proliferation. Oncology Reports (10.3892/or.2019.7445)
- Hao, C.et al. 2019. OPN promotes the aggressiveness of non-small-cell lung cancer cells through the activation of the RON tyrosine kinase. Scientific Reports 9(1), article number: 18101. (10.1038/s41598-019-54843-2)
- Tan, W.et al. 2019. Incorporating MicroRNA into molecular phenotypes of circulating tumor cells enhances the prognostic accuracy for patients with metastatic breast cancer. Oncologist 24, pp. e1044-e1054. (10.1634/theoncologist.2018-0697)
- Dart, D. A., Ashelford, K. and Jiang, W. G. 2019. AR mRNA Stability is increased with AR-antagonist resistance via 3' UTR variants. Endocrine Connections (10.1530/EC-19-0340)
- Huang, J.et al. 2019. Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells. Cancer Cell International 19(1), article number: 306. (10.1186/s12935-019-1033-5)
- Sanders, A.et al. 2019. Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination. Oncotarget 10(59), pp. 6362-6377. (10.18632/oncotarget.27279)
- Dart, D. A.et al. 2019. MiR-221 is specifically elevated in PC3 cells and its deletion reduces adhesion, motility and growth. Anticancer Research 39(10), pp. 5311-5327. (10.21873/anticanres.13724)
- Zhao, C.et al. 2019. Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancer. Cancer Letters 453, pp. 107-121. (10.1016/j.canlet.2019.03.043)
- Bosanquet, D. C.et al. 2019. Development and validation of a gene expression test to identify hard-to-heal chronic venous leg ulcers. British Journal of Surgery 106(8), pp. 1035-1042. (10.1002/bjs.11161)
- Zhong, W.et al. 2019. Effect of younger age on survival outcomes in T1N0M0 breast cancer: A propensity score matching analysis. Journal of Surgical Oncology 119(8), pp. 1039-1046. (10.1002/jso.25457)
- Xu, Y.et al. 2019. BDNF activates TrkB/PLCγ1 signaling pathway to promote proliferation and invasion of ovarian cancer cells through inhibition of apoptosis. European Review for Medical and Pharmacological Sciences 23(12), pp. 5093-5100. (10.26355/eurrev_201906_18173)
- Wazir, U.et al. 2019. Correlation of TERT and stem cell markers in the context of human breast cancer. Cancer Genomics and Proteomics 16(2), pp. 121-127. (10.21873/cgp.20117)
- Li, S.et al. 2019. Differential expression and functions of Ehm2 transcript variants in lung adenocarcinoma. International Journal of Oncology (10.3892/ijo.2019.4732)
- Fosu-Mensah, N. A.et al. 2019. The discovery of purine-based agents targeting triple-negative breast cancer and the αB-crystallin/VEGF protein-protein interaction. Medicinal Chemistry Research 28(2), pp. 182-202. (10.1007/s00044-018-2275-9)
- Kourti, M.et al. 2019. Repurposing old carbon monoxide-releasing molecules towards the anti-angiogenic therapy of triple-negative breast cancer. Oncotarget 10(10), pp. 1132-1148. (10.18632/oncotarget.26638)
- Kourti, M.et al. 2019. Structural modifications on CORM-3 lead to enhanced anti-angiogenic properties against triple-negative breast cancer cells. Medicinal Chemistry 15 (10.2174/1573406415666191206102452)
2018
- Yang, W.et al. 2018. Effects of lidocaine and ropivacaine on gastric cancer cells through down-regulation of ERK1/2 phosphorylation in vitro. Anticancer Research 38(12), pp. 6729-6735. (10.21873/anticanres.13042)
- Flamini, V.et al. 2018. Distinct mechanisms by which two forms of miR-140 suppress the malignant properties of lung cancer cells. Oncotarget 2018(9) (10.18632/oncotarget.26356)
- Collins, R.et al. 2018. Mechanistic insights of epithelial protein lost in neoplasm in prostate cancer metastasis. International Journal of Cancer 143(10), pp. 2537-2550. (10.1002/ijc.31786)
- Zhao, H.et al. 2018. DOK7V1 influences the malignant phenotype of lung cancer cells through PI3K/AKT/mTOR and FAK/paxillin signaling pathways. International Journal of Oncology (10.3892/ijo.2018.4624)
- Gera, R.et al. 2018. mRNA Expression of CDK2AP1 in human breast cancer: correlation with clinical and pathological parameters. Cancer Genomics and Proteomics 15(6), pp. 447-452. (10.21873/cgp.20103)
- Dart, D. A.et al. 2018. Novel trifluoromethylated enobosarm analogues with potent antiandrogenic activity in vitro and tissue selectivity in vivo. Molecular Cancer Therapeutics 17(9), pp. 1846-1858. (10.1158/1535-7163.MCT-18-0037)
- Li, L.et al. 2018. Psoriasin overexpression confers drug resistance to cisplatin by activating ERK in gastric cancer. International Journal of Oncology 53(3), pp. 1171-1182. (10.3892/ijo.2018.4455)
- Harries, R. L.et al. 2018. Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo. Oncotarget 9(27), pp. 19192-19202. (10.18632/oncotarget.24953)
- Ma, S.et al. 2018. CLDN5 affects lncRNAs acting as ceRNA dynamics contributing to regulating blood-brain barrier permeability in tumor brain metastasis. Oncology Reports 39(3), pp. 1441-1453. (10.3892/or.2018.6208)
- Owen, S.et al. 2018. Key factors in breast cancer dissemination and establishment at the bone: past, present and future perspectives. In: Song, E. and Hu, H. eds. Translational Research in Breast Cancer:Biomarker Diagnosis, Targeted Therapies and Approaches to Precision., Vol. 1026. Advances in Experimental Medicine and Biology Singapore: Kluwer, pp. 197-216., (10.1007/978-981-10-6020-5_9)
- Riaz, S. K.et al. 2018. Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer. Cell Communication and Signaling 16, article number: 3. (10.1186/s12964-017-0213-y)
- Xie, M.et al. 2018. MicroRNA-1 acts as a tumor suppressor microRNA by inhibiting angiogenesis-related growth factors in human gastric cancer. Gastric Cancer 21(1), pp. 41-54. (10.1007/s10120-017-0721-x)
- Jia, J.et al. 2018. Fibroblast activation protein-α promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways. International Journal of Molecular Medicine 41(1), pp. 275-283. (10.3892/ijmm.2017.3224)
2017
- Laprevotte, E.et al. 2017. The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway. Oncotarget 8, pp. 113360-113372. (10.18632/oncotarget.23008)
- Ma, S.et al. 2017. Claudin-5 regulates blood-brain barrier permeability by modifying brain microvascular endothelial cell proliferation, migration, and adhesion to prevent lung cancer metastasis. CNS Neuroscience & Therapeutics 23(12), pp. 947-960. (10.1111/cns.12764)
- Xin, L.et al. 2017. The era of multigene panels comes? The clinical utility of Oncotype DX and MammaPrint. World Journal of Oncology 8(2), pp. 34-40. (10.14740/wjon1019w)
- Yuan, Z.et al. 2017. Lessons From managing the breast malignant adenomyoepithelioma and the discussion on treatment strategy. World Journal of Oncology 8(4), pp. 126-131. (10.14740/wjon1055e)
- Tao, T.et al. 2017. PDZK1 inhibits the development and progression of renal cell carcinoma by suppression of SHP-1 phosphorylation. Oncogene 36, pp. 6119-6131. (10.1038/onc.2017.199)
- Zhao, H.et al. 2017. The effect of aurora kinase inhibitor on adhesion and migration in human breast cancer cells and clinical implications. World Journal of Oncology 8(5), pp. 151-161. (10.14740/wjon1062w)
- Dart, A. D., Uysal-Onganer, P. and Jiang, W. G. 2017. Prostate-specific PTen deletion in mice activates inflammatory microRNA expression pathways in the epithelium early in hyperplasia development. Oncogenesis 6(12), article number: 400. (10.1038/s41389-017-0007-5)
- Cai, S.et al. 2017. Kidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways (Review). International Journal of Molecular Medicine 40(4), pp. 965-971. (10.3892/ijmm.2017.3093)
- Zabkiewicz, C.et al. 2017. Bone morphogenetic proteins, breast cancer, and bone metastases: striking the right balance. Endocrine-Related Cancer 24(10), pp. R349-R66. (10.1530/ERC-17-0139)
- Zhao, Z.et al. 2017. Reduced expression of RanBPM Is associated with poorer survival from lung cancer and increased proliferation and invasion of lung cancer cells in vitro. Anticancer Research 37(8), pp. 4389-4397. (10.21873/anticanres.11833)
- Zhao, Q.et al. 2017. Protein of vascular endothelial growth inhibitor 174 inhibits epithelial-mesenchymal transition in renal cell carcinoma in vivo. Anticancer Research 37(8), pp. 4269-4275. (10.21873/anticanres.11819)
- Cui, Y.et al. 2017. Knockdown of EPHA1 using CRISPR/CAS9 suppresses aggressive properties of ovarian cancer cells. Anticancer Research 37(8), pp. 4415-4424. (10.21873/anticanres.11836)
- Yuan, Z.et al. 2017. Application of localization and needle placement guided by mammographic, ultrasound and fiberoptic ductoscopy for resection of non-palpable breast lesions. Anticancer Research 37(8), pp. 4523-4527. (10.21873/anticanres.11849)
- Du, P.et al. 2017. Reduced expression of Metastasis Suppressor-1 (MTSS1) accelerates progression of human bladder uroepithelium cell carcinoma. Anticancer Research 37(8), pp. 4499-4505. (10.21873/anticanres.11846)
- Yin, J.et al. 2017. Overexpression of EPHB4 Is associated with poor survival of patients with gastric cancer. Anticancer Research 37(8), pp. 4489-4497. (10.21873/anticanres.11845)
- Kiran Riaz, S.et al. 2017. Transcriptional profiling of sonic hedgehog in a prospective cohort of breast cancer in a Pakistani population. Anticancer Research 37(8), pp. 4449-4454. (10.21873/anticanres.11840)
- Yang, F.et al. 2017. NHERF1 suppresses lung cancer cell migration by regulation of epithelial-mesenchymal transition. Anticancer Research 37(8), pp. 4405-4414. (10.21873/anticanres.11835)
- Li, L.et al. 2017. Clinical correlation between WISP2 and β--Catenin in gastric cancer. Anticancer Research 37(8), pp. 4469-4473. (10.21873/anticanres.11842)
- Uhercik, M.et al. 2017. Clinical significance of PD1 and PDL1 in human breast cancer. Anticancer Research 37(8), pp. 4249-4254. (10.21873/anticanres.11817)
- Liang, G.et al. 2017. HIF1α-associated circDENND4C promotes proliferation of breast cancer cells in hypoxic environment. Anticancer Research 37(8), pp. 4337-4343. (10.21873/anticanres.11827)
- Sobkowicz, A. D.et al. 2017. Potential implication of Paxillin in cancer establishment within the bone environment. Anticancer Research 37(8), pp. 4255-4268. (10.21873/anticanres.11818)
- Flamini, V., Jiang, W. G. and Cui, Y. 2017. Therapeutic role of MiR-140-5p for the treatment of non-small cell lung cancer. Anticancer Research 37(8), pp. 4319-4327. (10.21873/anticanres.11825)
- Yu, Z.et al. 2017. Expression of osteoprotegrin is enhanced in lung cancer tissues and promotes aggressive cellular traits in H3122 lung cancer cells. Anticancer Research 37(8), pp. 4277-4283. (10.21873/anticanres.11820)
- Liu, Z.et al. 2017. High-efficient screening method for identification of key genes in breast cancer through microarray and bioinformatics. Anticancer Research 37(8), pp. 4329-4335. (10.21873/anticanres.11826)
- Zheng, F.et al. 2017. The axis of CXCR4/SDF-1 plays a role in colon cancer cell adhesion through regulation of the AKT and IGF1R signalling pathways. Anticancer Research 37(8), pp. 4361-4369. (10.21873/anticanres.11830)
- Zhao, Q.et al. 2017. Identification of novel proteins interacting with vascular endothelial growth inhibitor 174 in renal cell carcinoma. Anticancer Research 37(8), pp. 4379-4388. (10.21873/anticanres.11832)
- Tong, S.et al. 2017. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma. Scientific Reports 7(1), article number: 5599. (10.1038/s41598-017-06098-y)
- Liu, Z.et al. 2017. Hepatitis B virus reactivation in breast cancer patients undergoing chemotherapy: A review and meta-analysis of prophylaxis management. Journal of Viral Hepatitis 24(7), pp. 561-572. (10.1111/jvh.12672)
- Zabkiewicz, C.et al. 2017. Increased expression of follistatin in breast cancer reduces invasiveness and clinically correlates with better survival. Cancer Genomics Proteomics 14(4), pp. 241-251. (10.21873/cgp.20035)
- Hu, T.et al. 2017. Overexpression of activin receptor-like kinase 7 in breast cancer cells is associated with decreased cell growth and adhesion.. Anticancer Research 37, pp. 3441-3451. (10.21873/anticanres.11712)
- Lopes-Bastos, B.et al. 2017. Association of breast carcinoma growth with a non-canonical axis of IFNγ/IDO1/TSP1. Oncotarget (10.18632/oncotarget.18781)
- Cui, Y.et al. 2017. MicroRNA-7 suppresses the homing and migration potential of human endothelial cells to highly metastatic human breast cancer cells. British Journal of Cancer 117, pp. 89-101. (10.1038/bjc.2017.156)
- Malik, M. F. A.et al. 2017. Role of Plexin B1 in a breast cancer cohort of Pakistani patients and its contribution towards cancer metastasis as indicated by an in vitro model. Anticancer Research 37(8), pp. 4483-4488. (10.21873/anticanres.11844)
- Yang, W.et al. 2017. The effects of anesthetics on recurrence and metastasis of cancer, and clinical implications. World Journal of Oncology 8(3), pp. 63-70. (10.14740/wjon1031e)
- Jia, S.et al. 2017. Association of Wnt1-inducible signaling pathway protein-1 with the proliferation, migration and invasion in gastric cancer cells. Tumor Biology 39(6) (10.1177/1010428317699755)
- Owen, S.et al. 2017. The clinical and biological implications of the focal adhesion kinase pathway in ShenLingLan mediated suppression of cellular migration of ovarian cancer cells. Journal of Cancer Research & Therapy 5, pp. 24-31. (10.14312/2052-4994.2017-5)
- Koushyar, S.et al. 2017. The prohibitin-repressive interaction with E2F1, is rapidly inhibited by androgen signalling in prostate cancer cells. Oncogenesis 6, pp. e3333. (10.1038/oncsis.2017.32)
- Rangaraj, A.et al. 2017. Molecular and cellular impact of Psoriasin (S100A7) on the healing of human wounds. Experimental and Therapeutic Medicine 13(5), pp. 2151-2160. (10.3892/etm.2017.4275)
- Liu, Z.et al. 2017. Hey factors at the crossroad of tumorigenesis and clinical therapeutic modulation of Hey for anticancer treatment. Molecular Cancer Therapeutics 16(5), pp. 775-786. (10.1158/1535-7163.MCT-16-0576)
- Hao, C.et al. 2017. OPN-a splicing variant expression in non-small cell lung cancer and its effects on the bone metastatic abilities of lung cancer cells in vitro. Anticancer Research 37(5), pp. 2245-2254. (10.21873/anticanres.11561)
- Chen, G.et al. 2017. The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer. Oncology Reports 37(5), pp. 2695-2701. (10.3892/or.2017.5538)
- Liu, Y.et al. 2017. Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression. International Journal of Oncology 50(5), pp. 1491-1500. (10.3892/ijo.2017.3953)
- Hao, C.et al. 2017. Human osteopontin: potential clinical applications in cancer (Review). International Journal of Molecular Medicine (10.3892/ijmm.2017.2964)
- Ahmad, A.et al. 2017. KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer. PLoS ONE 12(4), article number: e0175058. (10.1371/journal.pone.0175058)
- Sun, P.et al. 2017. Dual roles of protein tyrosine phosphatase kappa in coordinating angiogenesis induced by pro-angiogenic factors. International Journal of Oncology 50(4), pp. 1127-1135. (10.3892/ijo.2017.3884)
- Ismail, A. F.et al. 2017. PAK5 mediates cell: cell adhesion integrity via interaction with E-cadherin in bladder cancer cells. Biochemical Journal 474(8), pp. 1333-1346. (10.1042/BCJ20160875)
- Frugtniet, B. A.et al. 2017. Neural Wiskott-Aldrich syndrome protein (nWASP) is implicated in human lung cancer invasion. BMC Cancer 17(1), article number: 224. (10.1186/s12885-017-3219-3)
- Cai, S.et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37(3), pp. 1707-1715. (10.3892/or.2017.5394)
- Owen, S.et al. 2017. ShenLingLan influences the attachment and migration of ovarian cancer cells potentially through the GSK3 pathway. Medicines 7, pp. 1-11.
- Li, J.et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Kourti, M., Jiang, W. and Cai, J. 2017. Aspects of carbon monoxide in form of CO-releasing molecules used in cancer treatment: More light on the way. Oxidative Medicine and Cellular Longevity 2017, article number: 9326454. (10.1155/2017/9326454)
- Wang, Z.et al. 2017. Poly lactic-co-glycolic acid controlled delivery of Disulfiram to target liver cancer stem-like cells. Nanomedicine: Nanotechnology, Biology and Medicine 13(2), pp. 641-657. (10.1016/j.nano.2016.08.001)
- Ablin, R. J., Owen, S. and Jiang, W. 2017. Prostate transglutaminase (TGase-4) induces epithelial-to-mesenchymal transition in prostate cancer cells. Anticancer Research 37(2), pp. 481-488. (10.21873/anticanres.11340)
- Hao, C.et al. 2017. The clinical significance of osteopontin (OPN) in non-small cell lung cancer and its biological impact on lung cancer cells. European Journal of Cancer 72(S1), pp. S182. (10.1016/S0959-8049(17)30663-9)
- Zheng, F.et al. 2017. CXCR4 promotes adhesion capacity and activates the AKT signalling pathway in colorectal cancer cells. European Journal of Cancer 72(S1), pp. S68. (10.1016/S0959-8049(17)30302-7)
- Yang, X.et al. 2017. A novel NHERF1 mutation in human breast cancer and effects on malignant progression. Anticancer Research 37(1), pp. 67-73. (10.21873/anticanres.11290)
- Gu, Y.et al. 2017. NHERF1 regulates the progression of colorectal cancer through the interplay with VEGFR2 pathway. Oncotarget 8(5), pp. 7753-7765. (10.18632/oncotarget.13949)
- Telford, E., Jiang, W. G. and Martin, T. A. 2017. HAVcR-1 involvement in cancer progression. Histology and Histopathology 32, pp. 121-128. (10.14670/HH-11-817)
- Feng, Y.et al. 2017. In vitro significance of SOCS-3 and SOCS-4 and potential mechanistic links to wound healing. Scientific Reports 7(1), article number: 6715. (10.1038/s41598-017-06886-6)
2016
- Cai, J. and Jiang, W. 2016. Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids. Oncotarget 7(52), pp. 86374-86387. (10.18632/oncotarget.13413)
- Feng, Y.et al. 2016. Expression of the SOCS family in human chronic wound tissues: Potential implications for SOCS in chronic wound healing. International Journal of Molecular Medicine 38(5), pp. 1349-1358. (10.3892/ijmm.2016.2733)
- Shi, L.et al. 2016. Clinical and therapeutic implications of follistatin in solid tumours. Cancer Genomics and Proteomics 13(6), pp. 425-435.
- Escudero-Esparza, A.et al. 2016. Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer. Oncotarget 7, pp. 76920-76933. (10.18632/oncotarget.12729)
- Ye, L. and Jiang, W. G. 2016. Bone morphogenetic proteins in tumour associated angiogenesis and implication in cancer therapies. Cancer Letters 380(2), pp. 586-597. (10.1016/j.canlet.2015.10.036)
- Li, J.et al. 2016. Differential expression of CCN family members CYR611, CTGF and NOV in gastric cancer and their association with disease progression. Oncology Reports (10.3892/or.2016.5074)
- Owen, S.et al. 2016. Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells. International Journal of Oncology 49, pp. 1839-1847. (10.3892/ijo.2016.3685)
- Xie, M.et al. 2016. Insights into roles of the miR-1, -133 and -206 family in gastric cancer (Review). Oncology Reports 36(3), pp. 1191-1198. (10.3892/or.2016.4908)
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2015
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2014
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2013
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2012
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2011
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2010
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- Martin, T. A., Mansel, R. E. and Jiang, W. G. 2010. Loss of occludin leads to the progression of human breast cancer. International Journal of Molecular Medicine 26(5), pp. 723-734. (10.3892/ijmm_00000519)
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2009
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2008
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2007
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2006
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2005
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2004
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2003
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2002
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2001
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2000
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1999
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1998
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- Jiang, W. G. 1998. Regulation of cell adhesion, a central mechanism in the anticancer action of essential fatty acids. International Journal of Molecular Medicine 1(3), pp. 621-625.
- Jiang, W. G. and Harding, K. G. 1998. Enhancement of wound tissue expansion and angiogenesis by matrix-embedded fibroblast (dermagraft), a role of hepatocyte growth factor/scatter factor. International Journal of Molecular Medicine 2, pp. 203-210.
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1997
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1996
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1995
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- Jiang, W. G.et al. 1995. Inhibition of HGF/SF-induced tumor-cell membrane ruffling by calcium signalling. British Journal of Surgery 82(5), pp. 682-683.
- Jiang, W. G.et al. 1995. Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. British Journal of Cancer 71(4), pp. 744-752. (10.1038/bjc.1995.145)
- Jiang, W. G. 1995. Membrane ruffling of cancer cells: a parameter of tumour cell motility and invasion. European Journal of Surgical Oncology (EJSO) 21, pp. 307-309. (10.1016/S0748-7983(95)91690-3)
- Hiscox, S.et al. 1995. Inhibition of cancer cell motility and invasion by interleukin-12. Clinical & Experimental Metastasis 13(5), pp. 396-404. (10.1007/BF00121916)
- Jiang, W. G.et al. 1995. Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor (HGF/SF). Biochemical and Biophysical Research Communications 217(3), pp. 1062-1069. (10.1006/bbrc.1995.2877)
1994
- Jiang, W.et al. 1994. Induction of motility and invasion by interleukin-3 on human colonic-cancer cells. British Journal of Surgery 81(5), pp. 761-761.
- Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Neutrophil priming by cytokines in patients with obstructive jaundice.. HPB Surgery 7(4), pp. 281-289. (10.1155/1994/74202)
- Jiang, W. G. 1994. In-vitro models of cancer invasion and metastasis: recent developments. European Journal of Surgical Oncology (EJSO) 20, pp. 493-499.
- Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Molecular and cellular basis of cancer invasion and metastasis: Implications for treatment. British Journal of Surgery 81(11), pp. 1576-1590. (10.1002/bjs.1800811107)
- Jiang, W. G. and Puntis, M. D. A. 1994. Effects of gamma linolenic acid and lithium linolinate on human monocytes and hepatoma. In: Horrobin, D. F. ed. New approaches to cancer treatment: Unsaturated lipids and photodynamic therapy. Edinburgh: Churchill-Livingstone, pp. 40-67.
1993
- Jiang, W. G.et al. 1993. Regulation of spreading and growth of colon cancer cells by hepatocyte growth factor.. Clinical and Experimental Metastasis 11(3), pp. 235-242. (10.1007/BF00121166)
- Jiang, W. G. and Puntis, M. C. 1993. Monocyte secretion of beta-hexosaminidase in patients with obstructive jaundice. HPB Surgery 7, pp. 15-23.
- Jiang, W. G., Hallett, M. B. and Puntis, M. C. A. 1993. Hepatocyte growth factor/scatter factor, liver regeneration and cancer metastasis. British Journal of Surgery 80(11), pp. 1368-1373. (10.1002/bjs.1800801104)
1992
- Jiang, W. G.et al. 1992. Neutrophil priming by hepatocyte growth factor, a novel cytokine. Immunology 77(1), pp. 147-149.
- Jiang, W. G., Puntis, M. and Hallett, M. B. 1992. U937 cells stimulated with opsonised zymozan particles provide a convenient laboratory source of tumour necrosis factor α. Journal of Immunological Methods 152(2), pp. 201-207. (10.1016/0022-1759(92)90141-F)
- Molecular Pathology Module
- HGF/cMET in the osteoblastic metastasis of prostate cancer, molecular, cellular and therapeutic implications, in collaboration with Professor Malcolm D Mason
- Molecular finger printing of genes linked to cancer progression
- Novel molecular wound healing signature, in collaboration with Professor Keith Harding
- The molecular, cellular and clinical impacts of SOCS, suppressor of cytokine signalling, in human wound healing, in collaboration with Professor Keith Harding
- Anti-metastasis (including peritoneal metastasis) medicines, in collaboration with Peking University and Yiling Research Institute (Professor Jiafu Ji and Professor Yiling Wu)
- Brain Metastasis Research Platform, in collaboration with Capital Medical University (Professors Junqi He and Wei Ding)
- Evaluation of transglutaminase-4 as a therapeutic target and diagnostic tool in human prostate cancer, in collaboration with Professor Malcolm D Mason and Professor Richard J Ablin (University of Arizona)
- Biomarkers in human colorectal cancer research programme, in collaboration with Capital Medical University (Professors Junqi He and Wei Ding)
- Cancer Metastasis Platform, in collaboration with Wales Life Science Network