Professor Wen Jiang

Chair

: jiangw@cardiff.ac.uk
: +44 (0)29 2068 7065
: Ground Floor, Henry Wellcome Building for Biomedical Research, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN

: Available for postgraduate supervision

I have a long-standing interest in cancer metastasis and from 1987, my main research interest has been on the molecular and cellular basis of cancer invasion and metastasis and therapeutic aspects of targeting cancer metastasis. I have been particularly interested in the bone, peritoneal and brain metastasis from primary tumours including breast, prostate, lung, GI cancers. My research has been conducted in Cardiff's School of Medicine and I have collaborated widely with colleagues in the UK, China, Europe, North America and Asia.

Education and qualifications:

1995, MD, University of Wales College of Medicine
1984, MB/ BCh in Clinical Medicine, Peking University Health Science Centre (Previously Beijing Medical University)

Career overview:

2014 - present: University Dean of International, Cardiff University
2012 - present: Director of Cardiff China Medical Research Collaborative
2012 - present: Quality and Safety Improvement Faculty, National Health Service/UHB, National Health Service
2012 - present: Academic Director for International Relations, Cardiff University
2004 - present: Professor of Surgery and Tumour Biology, Cardiff University School of Medicine
2003 - 2004: Reader, University of Wales College of Medicine
1997 - 2003: Senior Lecturer, University of Wales College of Medicine
1996 - 1997: Senior Fellow, University of Wales College of Medicine
1989 - 1996: Research Fellow, University of Wales College of Medicine (currently Cardiff University's School of Medicine)
1987 - 1989: Chief Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing
1984 - 1987: Surgical Resident, Department of General Surgery, Peking University First Hospital, Beijing

Honours and awards

Fellow of the Royal Society of Biology
Fellow of the Royal Society of Medicine
Honorary professorship at Peking University
Honorary professorship at Capital Medical University
Honorary professorship at Inner Mongolia University
Honorary professorship at QingDao University
International consultant for Beijing Lung Cancer Centre

Recent awards include:

Member of the Most Excellent Order of the British Empire
Marquis Who's Who as Prominent Cancer Researcher
Outstanding Achievement Award, 19th World Congress of Oncology, Athens, Greece, October 2014
Super Professor in America's Academic Row, June 2015

Professional memberships

Member of the American Association for Cancer Research (AACR)
Member of the British Association for Cancer Research (BACR)
Member of the European Association for Cancer Research (EACR)

Speaking engagements

Recent speaking engagements include:

2017: International Gastic Cancer Conference
2016: Gordon Conference, Gerona, Spain
2016: British Society of Pharmacology
2016: GOC 2016, Prague
2016: 12th International Conference on Collateral Disease (Oncology Forum), Shanghai, China
2015: 11th International Conference on Collateral Disease, Shijiazhuang, China
2014: Peking University Postgraudate Society
2014: 19th World Congress on Advances in Oncology, Athens
2014: 9th International Conference of Anticancer Research, Sithonia
2013: Phoenix TV, Chinese Medicine in cancer therapies
2013: BBC report on new medicine in cancer treatment

Committees and reviewing

2014 - present: Member of the University International Board

Other academic activities:

Editorship:

Editor-in-Chief: World Journal of Oncology
Editor-in-Chief: Cancer Metastasis, Biology and Treatment http://www.springer.com/series/5761
Editor-in-Chief: Journal of Molecular and Genetic Medicine http://www.omicsonline.com/open-access/molecular-genetic-medicine.php

Editorial Board membership includes:

Member of the editorial board of the International Journal of Molecular Medicine, from 1999
Advisory Board Member, ‘Advances in Therapy’, from 2008
Editorial Board Member, ‘Current Oncology’, from 2008
Editorial Board Member, ‘Journal of Surgical Oncology’, from 2008
Editorial Board Member, ‘Current Signal Transduction Therapy’, from 2009
Editorial Board Member, ‘World Journal of Gastroenterology’, from 2009
Editorial Board Member, ‘Experimental and Therapeutic Medicine’, from 2009
Editorial Board Member, ‘World Journal of Clinical Oncology’, From 2010
Editorial Board Member, ‘World Journal of Oncology’, From 2010
Editorial Board Member, ‘Chinese Journal of Cancer Research’, From 2010
Editorial Board Member, ‘Current Cancer Therapy Reviews’, From 2010
Editorial Board Member, ‘International Journal of Oncology'', from 2011
Editorial Board Member, ‘Translational Medicine: Current Research'', from 2011
Editorial Board Member, ‘Translational Gastrointestinal Cancer'', from 2011
Editorial Board Member, ‘Biomedical Reports'', from 2012
Editorial Board Member, ‘World Journal of Medical Genetics (WJMG)'', from 2012
Academic consultant, 'Antitumour Pharmacy', from 2012
Editorial Board Member: 'Journal of Cancer Research and Therapy', from 2012
Editorial Board Member: 'Angiology', from 2012
Editorial Board Member: 'AO Translational Research', from 2013
Editorial Board Member: 'Chinese Journal of Biology', from 2013
Editorial Board Member: 'Academic Journal of Capital Medical University', from 2013
Editorial Board Member: 'Cancer Genomics and Proteomics', from 2014
Editorial Board Member: 'Insight of Medical Physics', from 2015
Editorial Board Member: 'Cancer Translational Medicine', from 2015
Editorial Board Member: 'Biochemical and Biophysical Acta (BBA) Clinical'', from 2015
Editorial Board Member: 'Cancer Hypothesis', from 2016

Books published

‘Cancer Metastasis, molecular and cellular basis and clinical intervention’, Editors Wen G Jiang and Robert E Mansel, Kluwer Academic Publishers, 2000 (ISBN 0-7923-6395-7). (http://www.springer.com/gb/book/9780792363958)

‘Growth Factors and their receptors in cancer metastasis’, Editors Wen G Jiang, Toshikazu Nakamura and Kunio Matsumoto, Kluwer Academic Publishers, 2001 (ISBN 0-7923-7141-0) (http://www.springer.com/gb/book/9780792371410)

‘Breast Cancer Metastasis’, Editors Robert E Mansel, Oystein Fodstad and Wen G Jiang, Spinger Publishers, 2007, ISBN: 978-1-4020-5866-0. (http://www.springer.com/gb/book/9781402058660)

'Electric Cell-Substrate Sensing in the investigation of cancer and cancer metastasis'. Wen G Jiang. Springer Publishers, 2012. ISBN 978-94-007-4926-9 (http://www.springer.com/biomed/cancer/book/978-94-007-4926-9)

'Tight junctions in cancer metastasis'. TA Martin and WG Jiang. Springer Publishers, March 2013 (ISBN 978-94-007-6027-1). (http://www.springer.com/gb/book/9789400760271)

2011

Sanders, A. J., Martin, T. A., Ye, L., Mason, M. D. and Jiang, W. G. 2011. EPLIN is a negative regulator of prostate cancer growth and invasion. The Journal of Urology 186(1), pp. 295-301. (10.1016/j.juro.2011.03.038)
Yuan, Z., Sanders, A. J., Ye, L., Wang, Y. and Jiang, W. G. 2011. Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP-9. Oncology Reports 26(1), pp. 237-245. (10.3892/or.2011.1271)
Jiang, W. G. and Ablin, R. J. 2011. Prostate transglutaminase: a unique transglutaminase and its role in prostate cancer. Biomarkers in Medicine 5(3), pp. 285-291. (10.2217/bmm.11.36)
Martin, T. A., Harrison, G. M., Mason, M. D. and Jiang, W. G. 2011. HAVcR-1 reduces the integrity of human endothelial tight junctions. Anticancer Research 31(2), pp. 467-473.
Ye, L., Mason, M. D. and Jiang, W. G. 2011. Bone morphogenetic protein and bone metastasis, implication and therapeutic potential. Frontiers in Bioscience 16, pp. 865-897.
Webb, S. L., Sanders, A. J., Mason, M. D. and Jiang, W. G. 2011. Type II transmembrane serine protease (TTSP) deregulation in cancer. Frontiers in Bioscience 16, pp. 539-552.
Yuan, Z., Sanders, A. J., Ye, L., Wang, Y. and Jiang, W. G. 2011. Prognostic value of the human antigen R (HuR) in human breast cancer: high level predicts a favourable prognosis. Anticancer Research 31(1), pp. 303-310.
Al-Rawi, A. A. M. and Jiang, W. G. 2011. Lymphangiogenesis and cancer metastasis. Frontiers in Bioscience 16(1), pp. 723-739. (10.2741/3715)
Cheng, S., Martin, T. A., Teng, X. and Jiang, W. G. 2011. Putative breast tumor suppressor TACC2 suppresses the aggressiveness of breast cancer cells through a PLCγ pathway. Current Signal Transduction Therapy 6(1), pp. 55-64. (10.2174/157436211794109361)
Yu, H., Zhang, Y., Ye, L. and Jiang, W. G. 2011. The FERM family proteins in cancer invasion and metastasis. Frontiers in Bioscience 16(1), pp. 1536-1550. (10.2741/3803)
Rangaraj, A., Ye, L., Harding, K. G. and Jiang, W. G. 2011. Psoriasin (S100A7) gene and its functions in keratinocytes, the main cell types during wound healing [Abstract]. Wound Repair and Regeneration 19(2), pp. A45. (10.1111/j.1524-475X.2010.00670.x)
Rangaraj, A., Ye, L., Harding, K. G. and Jiang, W. G. 2011. BCL-2 interaction killer, BIK in keratinocyte cellular function and wound healing [Abstract]. Wound Repair and Regeneration 19(2), pp. A45. (10.1111/j.1524-475X.2010.00670.x)
Bosanquet, D. C., Sanders, A. J., Parr, C., Harding, K. G. and Jiang, W. G. 2011. The role of metastasis suppressor 1 (MTSS1) in angiogenesis [Abstract]. Wound Repair and Regeneration 19(2), pp. A14. (10.1111/j.1524-475X.2010.00670.x)
Bosanquet, D. C., Ye, L., Saravolac, V., Sanders, A. J., Rangaraj, A., Harding, K. G. and Jiang, W. G. 2011. Keratinocyte migration, wound healing and the role of the novel protein EHM2 [Abstract]. Wound Repair and Regeneration 19(2), pp. A14. (10.1111/j.1524-475X.2010.00670.x)
Bosanquet, D. C., Harding, K. G. and Jiang, W. G. 2011. Keratinocyte migration and MTSS1 (metastasis suppressor 1) [Abstract]. Wound Repair and Regeneration 19(2), pp. A14. (10.1111/j.1524-475X.2010.00670.x)
Bosanquet, D. C., Ye, L., Saravolac, V., Sanders, A. J., Rangaraj, A., Harding, K. G. and Jiang, W. G. 2011. The role of HuR in keratinocyte migration and wound healing [Abstract]. Wound Repair and Regeneration 19(2), pp. A14. (10.1111/j.1524-475X.2010.00670.x)
Jiang, W. G. and Matsumoto, K. 2011. Hepatocyte growth factor and its signalling, new horizons in medicine and therapies.. Current Signal Transduction Therapy 6(2), pp. 141-142.
Jiang, W. G. and Sanders, A. J. 2011. Hepatocyte growth factor is a potential lymphangiogenic factor: clinical implications. Current Signal Transduction Therapy 6(2), pp. 168-172. (10.2174/157436211795659900)
Martin, T. A., Mason, M. D. and Jiang, W. G. 2011. Hepatocyte growth factor signalling in cancer metastasis. Current Signal Transduction Therapy 6(2), pp. 180-190. (10.2174/157436211795659991)
Lane, J., Martin, T. A. and Jiang, W. G. 2011. HGF and rhoGTPases in cancer cell motility. Current Signal Transduction Therapy 6(2), pp. 173-179. (10.2174/157436211795660052)
Li, J., Ye, L., Mansel, R. E. and Jiang, W. G. 2011. Potential prognostic value of repulsive guidance molecules in breast cancer.. Anticancer Research 31(5), pp. 1703-1711.
Du, P., Ye, L., Ruge, F., Yang, Y. and Jiang, W. G. 2011. Metastasis suppressor-1, MTSS1, acts as a putative tumour suppressor in human bladder cancer. Anticancer Research 31(10), pp. 3205-3212.
Ablin, R. J. and Jiang, W. G. 2011. The role of transglutaminases in the pathophysiology of prostate cancer. Current Oncology 18(5), pp. 241-242.
Escudero-Esparza, A., Jiang, W. G. and Martin, T. A. 2011. Claudin-5 participates in the regulation of endothelial cell motility. Molecular and Cellular Biochemistry 362(1-2), pp. 71-85. (10.1007/s11010-011-1129-2)
Ruan, Q., Han, S., Jiang, W. G., Boulton, M. E., Chen, Z. J., Law, B. K. and Cai, J. 2011. B-Crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells. Molecular Cancer Research 9(12), pp. 1632-1643. (10.1158/1541-7786.MCR-11-0327)
Sanders, A. J., Jiang, D. G., Jiang, W. G., Harding, K. G. and Patel, G. K. 2011. Activated leukocyte cell adhesion molecule impacts on clinical wound healing and inhibits HaCaT migration. International Wound Journal 8(5), pp. 500-507. (10.1111/j.1742-481X.2011.00823.x)
Patani, N., Jiang, W. G. and Mokbel, K. 2011. Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer. Cancer Cell International 11, pp. 23-30. (10.1186/1475-2867-11-23)
Cai, J. et al. 2011. Placenta growth Factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability [RETRACTED]. PLoS ONE 6(3), article number: e18076. (10.1371/journal.pone.0018076)
Ablin, R. J., Kynaston, H., Mason, M. D. and Jiang, W. G. 2011. Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer. Journal of Translational Medicine 9, pp. 49-57. (10.1186/1479-5876-9-49)
Martin, T. A., Mason, M. D. and Jiang, W. G. 2011. Tight junctions in cancer metastasis. Frontiers in Bioscience 16(3), pp. 898-936. (10.2741/3726)
Escudero-Esparza, A., Jiang, W. G. and Martin, T. A. 2011. The Claudin family and its role in cancer and metastasis. Frontiers in Bioscience 16(3), pp. 1069-1083. (10.2741/3736)
Mustafa, N., Martin, T. A. and Jiang, W. G. 2011. Metastasis tumour suppressor-1 and the aggressiveness of prostate cancer cells. Experimental and Therapeutic Medicine 2(1), pp. 157-162. (10.3892/etm.2010.184)
Ge, Z., Sanders, A. J., Ye, L. and Jiang, W. G. 2011. Aberrant expression and function of death receptor-3 and death decoy receptor-3 in human cancer. Experimental and Therapeutic Medicine 2(2), pp. 167-172. (10.3892/etm.2011.206)
Minhas, U., Martin, T. A., Ruge, F., Harding, K. G. and Jiang, W. G. 2011. Pattern of expression of CCN family members Cyr61, CTGF and NOV in human acute and chronic wounds. Experimental and Therapeutic Medicine 2(4), pp. 641-645. (10.3892/etm.2011.256)
Li, J., Ye, L., Kynaston, H. and Jiang, W. G. 2011. Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of prostate cancer cells. International Journal of Oncology 40(2), pp. 544-550. (10.3892/ijo.2011.1251)
Awsare, N. S., Martin, T. A., Haynes, M. D., Matthews, P. N. and Jiang, W. G. 2011. Claudin-11 decreases the invasiveness of bladder cancer cells. Oncology Reports 25(6), pp. 1503-1509. (10.3892/or.2011.1244)
Ge, Z., Sanders, A. J., Ye, L., Wang, Y. and Jiang, W. G. 2011. Expression of death decoy receptor-3 (DcR3) in human breast cancer and its functional effects on breast cancer cells in vitro. Journal of Experimental Therapeautics and Oncology 9, pp. 109-118. (10.3892/or.2013.2259)

2010

Sanders, A. J., Ye, L., Mason, M. D. and Jiang, W. G. 2010. The impact of EPLINα (Epithelial protein lost in neoplasm) on endothelial cells, angiogenesis and tumorigenesis. Angiogenesis 13(4), pp. 317-326. (10.1007/s10456-010-9188-7)
Davies, S., Davies, M. L., Sanders, A. J., Parr, C., Torkington, J. and Jiang, W. G. 2010. Differential expression of the CCN family member WISP-1, WISP-2 and WISP-3 in human colorectal cancer and the prognostic implications. International Journal of Oncology 36(5), pp. 1129-1136. (10.3892/ijo_00000595)
Cai, W., Ye, L., Sun, J., Mansel, R. E. and Jiang, W. G. 2010. Expression of MLN64 influences cellular matrix adhesion of breast cancer cells, the role for focal adhesion kinase. International Journal of Molecular Medicine 25(4), pp. 573-580. (10.3892/ijmm_00000379)
Davies, S. and Jiang, W. G. 2010. ALCAM, activated leukocyte cell adhesion molecule, influences the aggressive nature of breast cancer cells, a potential connection to bone metastasis. Anticancer Research 30(4), pp. 1163-1168.
Ye, L., Chen, J., Xie, F., Yang, Y., Zhang, L. and Jiang, W. G. 2010. Expression of bone morphogenetic protein 7 in lung cancer and its biological impact on lung cancer cells. Anticancer Research 30(4), pp. 1113-1120.
Al Sarakbi, W., Reefy, S., Jiang, W. G., Roberts, T., Newbold, R. F. and Mokbel, K. 2010. Evidence of a tumour suppressor function for DLEC1 in human breast cancer.. Anticancer Research 30(4), pp. 1079-1082.
Davies, M. L., Parr, C., Sanders, A. J., Fodstad, O. and Jiang, W. G. 2010. The transcript expression and protein distribution pattern in human colorectal carcinoma reveal a pivotal role of COM-1/p8 as a tumour suppressor. Cancer Genomics and Proteomics 7(2), pp. 75-80.
Cheng, S., Douglas-Jones, A., Yang, X., Mansel, R. E. and Jiang, W. G. 2010. Transforming acidic coiled-coil-containing protein 2 (TACC2) in human breast cancer, expression pattern and clinical/prognostic relevance. Cancer Genomics and Proteomics 7(2), pp. 67-73.
Sasi, W., Jiang, W. G., Sharma, A. K. and Mokbel, K. 2010. The role of suppressors of cytokine signaling in human breast cancer. EJC Supplements 8(3), pp. 107-107.
Lane, J., Martin, T. A. and Jiang, W. G. 2010. Targeting RhoC by way of ribozyme trangene in human breast cancer cells and its impact on cancer invasion. World Journal of Oncology 1(1), pp. 7-13. (10.4021/wjon2010.01.1202)
Yu, H., Ye, L., Mansel, R. E., Zhang, Y. and Jiang, W. G. 2010. Clinical implications of the influence of Ehm2 on the aggressiveness of breast cancer cells through regulation of matrix metalloproteinase-9 expression. Molecular Cancer Research 8(11), pp. 1501-1512. (10.1158/1541-7786.MCR-10-0186)
Zhang, N., Sanders, A. J., Ye, L., Kynaston, H. and Jiang, W. 2010. Expression of vascular endothelial growth inhibitor (VEGI) in human urothelial cancer of the bladder and its effects on the adhesion and migration of bladder cancer cells in vitro. Anticancer Research 30(1), pp. 87-95.
Lane, J., Martin, T., McGuigan, C., Mason, M. and Jiang, W. 2010. The differential expression of hCNT1 and hENT1 i n breast cancer and the possible impact on breast cancer therapy. Journal of Experimental Therapeutics and Oncology 8(3), pp. 203-210.
Parr, C., Sanders, A. J. and Jiang, W. G. 2010. Hepatocyte growth factor activation inhibitors - therapeutic potential in cancer. Anti-Cancer Agents in Medicinal Chemistry 10(1), pp. 47-57.
Martin, T. A. and Jiang, W. G. 2010. Hepatocyte growth factor and cMET, new development in cancer therapies [Editorial]. Anti-Cancer Agents in Medicinal Chemistry 10(1), pp. 1.
Martin, T. A. and Jiang, W. G. 2010. Hepatocyte growth factor and its receptor signalling complex as targets in cancer therapy. Anti-Cancer Agents in Medicinal Chemistry 10(1), pp. 2-6.
Sanders, A. J., Webb, S. L., Parr, C., Mason, M. D. and Jiang, W. G. 2010. The type II transmembrane serine protease, matriptase-2: possible links to cancer ?. Anti-Cancer Agents in Medicinal Chemistry 10(1), pp. 64-69.
Jiang, W. G., Ye, L., Ablin, R. J., Kynaston, H. and Mason, M. D. 2010. The prostate transglutaminase, TGase-4, coordinates with the HGFL/MSP-RON system in stimulating the migration of prostate cancer cells. International Journal of Oncology 37(2), pp. 413-418. (10.3892/ijo_00000689)
Rangaraj, A., Ye, L., Patel, G. K., Price, P. E., Harding, K. G. and Jiang, W. G. 2010. The molecular and cellular roles of Psoriasin (S100A4) in human cutaneous wound healing [Abstract]. Wound Repair and Regeneration 18(6), pp. A92. (10.1111/j.1524-475X.2010.00633.x)
Rangaraj, A., Ye, L., Patel, G. K., Harding, K. G. and Jiang, W. G. 2010. The role of Bik1 (BCL-2 interaction killer) in wound healing [Abstract]. Wound Repair and Regeneration 18(6), pp. A92. (10.1111/j.1524-475X.2010.00633.x)
Minhas, U., Sanders, A. J., Patel, G. K., Harding, K. G. and Jiang, W. G. 2010. Activated leukocyte cell adhesion molecule (ALCAM) - biological impact on vascular endothelial cells [Abstract]. Wound Repair and Regeneration 18(6), pp. A89. (10.1111/j.1524-475X.2010.00633.x)
Jiang, W. G., Sanders, A. J. and Harding, K. G. 2010. Expression of vegi, vascular endothelial growth inhibitor, and its impact on cellular functions of keratinocytes [Abstract]. Wound Repair and Regeneration 18(6), pp. A84. (10.1111/j.1524-475X.2010.00633.x)
Jiang, W. G., Ye, L., Patel, G. K. and Harding, K. G. 2010. Expression of WAVEs, the WASP (Wiskott-Aldrich syndrome protein) family of verprolin homologous proteins, in human wound tissues and the cellular impact of WAVEs on keratinocytes [Abstract]. Wound Repair and Regeneration 18(6), pp. A84. (10.1111/j.1524-475X.2010.00633.x)
Martin, T. A., Mansel, R. E. and Jiang, W. G. 2010. Loss of occludin leads to the progression of human breast cancer. International Journal of Molecular Medicine 26(5), pp. 723-734. (10.3892/ijmm_00000519)
Yuan, Z., Sanders, A. J., Ye, L. and Jiang, W. G. 2010. HuR, a key post-transcriptional regulator, and its implication in progression of breast cancer. Histology and Histopathology 25(10), pp. 1331-1340.
Mokbel, K., Patani, N., Jiang, W. G. and Newbold, R. 2010. Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer. Journal of Carcinogenesis 9(1), pp. 9-17. (10.4103/1477-3163.72505)
Bokobza, S. M., Ye, L., Kynaston, H. and Jiang, W. G. 2010. Growth and differentiation factor-9 promotes adhesive and motile capacity of prostate cancer cells by up-regulating FAK and Paxillin via Smad dependent pathway. Oncology Reports 24(6), pp. 1653-1659. (10.3892/or_00001030)
Bokobza, S. M., Ye, L., Kynaston, H. and Jiang, W. G. 2010. GDF-9 promotes the growth of prostate cancer cells by protecting them from apoptosis. Journal of Cellular Physiology 225(2), pp. 529-536. (10.1002/jcp.22235)
Bokobza, S. M., Ye, L., Kynaston, H. and Jiang, W. G. 2010. Growth and differentiation factor 9 (GDF-9) induces epithelial-mesenchymal transition in prostate cancer cells. Molecular and Cellular Biochemistry 349(1-2), pp. 33-40. (10.1007/s11010-010-0657-5)
Ablin, R. J. and Jiang, W. G. 2010. All Fats are Not Bad: A Smart Lesson to be Learned [Editorial]. The Journal of Urology 183(1), pp. 13-14. (10.1016/j.juro.2009.11.001)
Fernando, H. S., Sanders, A. J., Kynaston, H. and Jiang, W. G. 2010. WAVE3 is associated with invasiveness in prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 28(3), pp. 320-327. (10.1016/j.urolonc.2008.12.022)
Jiang, W. G., Ye, L., Patel, G. K. and Harding, K. G. 2010. Expression of WAVEs, the WASP (Wiskott-Aldrich syndrome protein) family of verprolin homologous proteins in human wound tissues and the biological influence on human keratinocytes. Wound Repair and Regeneration 18(6), pp. 594-604. (10.1111/j.1524-475X.2010.00630.x)
Sasi, W., Jiang, W. G., Sharma, A. and Mokbel, K. 2010. Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer. BMC Cancer 10, pp. 178-189. (10.1186/1471-2407-10-178)
Chen, J., Xie, F., Zhang, L. and Jiang, W. G. 2010. iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway. BMC Cancer 10, pp. 1-6., article number: 694. (10.1186/1471-2407-10-694)
Patani, N., Douglas-Jones, A., Mansel, R. E., Jiang, W. G. and Mokbel, K. 2010. Tumour suppressor function of MDA-7/IL-24 in human breast cancer. Cancer Cell International 10, pp. 29-37. (10.1186/1475-2867-10-29)
Ye, L., Bokobza, S. M., Li, J., Moazzam, M., Chen, J., Mansel, R. E. and Jiang, W. 2010. Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer. Cancer Science 101(10), pp. 2137-2144. (10.1111/j.1349-7006.2010.01648.x)
Herman, F., Martin, T. A., Douglas-Jones, A., Kynaston, H. G., Mansel, R. E. and Jiang, W. G. 2010. Expression of the ERM family members (ezrin, radixin and moesin) in breast cancer. Experimental and Therapeutic Medicine 1(1), pp. 153-160. (10.3892/etm_00000025)
Escudero-Esparza, A., Martin, T. A., Douglas-Jones, A., Mansel, R. E. and Jiang, W. G. 2010. PGF isoforms, PLGF-1 and PGF-2 and the PGF receptor, neuropilin, in human breast cancer: prognostic significance. Oncology Reports 23(2), pp. 537-544. (10.3892/or_00000667)
Al-Reefy, S., Osman, H., Jiang, W. G. and Mokbel, K. 2010. Evidence for a pro-apoptotic function of RACK1 in human breast cancer [Letter]. Oncogene 29(41), pp. 5651. (10.1038/onc.2010.291)
Sanders, A. J., Guo, X., Mason, M. D. and Jiang, W. G. 2010. IL-17B can impact on endothelial cellular traits linked to tumour angiogenesis. Journal of Oncology 2010, article number: 817375. (10.1155/2010/817375)

2009

Zhang, N., Sanders, A. J., Ye, L., Kynaston, H. and Jiang, W. G. 2009. Vascular endothelial growth inhibitor, expression in human prostate cancer tissue and the impact on adhesion and migration of prostate cancer cells in vitro. International Journal of Oncology 35(6), pp. 1473-1480. (10.3892/ijo_00000466)
Ye, L., Bokobza, S. and Jiang, W. G. 2009. Bone morphogenetic proteins in development and progression of breast cancer and therapeutic potential (review). International Journal of Molecular Medicine 24(5), pp. 591-597. (10.3892/ijmm_00000269)
Malik, F. A., Sanders, A. J., Kayani, M. A. and Jiang, W. G. 2009. Effect of expressional alteration of KAI1 on breast cancer cell growth, adhesion, migration and invasion. Cancer Genomics and Proteomics 6(4), pp. 205-213.
Zhang, N., Sanders, A. J., Ye, L. and Jiang, W. G. 2009. Vascular endothelial growth inhibitor in human cancer (Review). International Journal of Molecular Medicine 24(1), pp. 3-8. (10.3892/ijmm_00000198)
Ye, L., Kynaston, H. and Jiang, W. G. 2009. Bone Morphogenetic Protein-10 suppresses the growth and aggressiveness of prostate cancer cells through a Smad independent pathway. The Journal of Urology 181(6), pp. 2749-2759. (10.1016/j.juro.2009.01.098)
Martin, T. A. and Jiang, W. G. 2009. Loss of tight junction barrier function and its role in cancer metastasis. Biochimica et Biophysica Acta (BBA) - Biomembranes 1788(4), pp. 872-891. (10.1016/j.bbamem.2008.11.005)
Malik, F. A., Sanders, A. J., Douglas-Jones, A. G., Mansel, R. E. and Jiang, W. G. 2009. Transcriptional and translational modulation of KAI1 expression in ductal carcinoma of the breast and the prognostic significance. International Journal of Molecular Medicine 23(2), pp. 273-278. (10.3892/ijmm_00000127)
Bokobza, S. M., Ye, L., Kynaston, H., Mansel, R. E. and Jiang, W. G. 2009. Reduced expression of BMPR-IB correlates with poor prognosis and increased proliferation of breast cancer cells. Cancer Genomics and Proteomics 6(2), pp. 101-108.
Minhas, U., Martin, T. A., Price, P. E., Harding, K. G. and Jiang, W. G. 2009. CCN family proteins in wound healing - a pivotal role? [Abstract]. Wound Repair and Regeneration 17(4), pp. A74. (10.1111/j.1524-475X.2009.00519.x)
Noble, S. I. R., Parr, C., Yee, L. and Jiang, W. G. 2009. The effects of metastasis supressor-1 gene on the migratory properties of non small cell lung cancer [Abstract]. Lung Cancer 63(S1), pp. S3. (10.1016/S0169-5002(09)70007-8)
Fernando, H. S., Kynaston, H. and Jiang, W. G. 2009. WASP and WAVE proteins: vital intrinsic regulators of cell motility and their role in cancer (Review). International Journal of Molecular Medicine 23(2), pp. 141-148. (10.3892/ijmm_00000111)
Malik, F. A., Sanders, A. J. and Jiang, W. G. 2009. KAI-1/CD82, The molecule and clinical implication in cancer and cancer metastasis. Histology and Histopathology 24(4), pp. 519-530.
Escudero-Esparza, A., Martin, T. A., Davies, M. L. and Jiang, W. G. 2009. PGF isoforms, PLGF-1 and PGF-2, in colorectal cancer and the prognostic significance. Cancer Genomics and Proteomics 6(4), pp. 239-246.
Kang, H., Escudero-Esparza, A., Douglas-Jones, A., Mansel, R. E. and Jiang, W. G. 2009. Transcript analyses of stromal cell derived factors (SDFs): SDF-2, SDF-4 and SDF-5 reveal a different pattern of expression and prognostic association in human breast cancer. International Journal of Oncology 35(1), pp. 205-211. (10.3892/ijo_00000330)
Bokobza, S. M., Ye, L. and Jiang, W. G. 2009. When BMP signalling goes wrong: the intracellular and molecular mechanisms of BMP sgnalling in cancer. Current Signal Transduction Therapy 4(3), pp. 174-195. (10.2174/157436209789057485)
Noble, S. I. R., Parr, C., Ye, L., Zhang, L. and Jiang, W. G. 2009. The impact of metastasis tumour supressor-1 (MTSS1) on the metastatic characteristics of non small cell lung cancer and its association with smoking history [Abstract]. Journal of Thoracic Oncology 4(9), pp. S630. (10.1097/JTO.0b013e3181b9c77e)
Parr, C. and Jiang, W. G. 2009. Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer. European Journal of Cancer 45(9), pp. 1673-1683. (10.1016/j.ejca.2009.02.019)
Jiang, W. G., Ablin, R. J., Kynaston, H. and Mason, M. D. 2009. The prostate transglutaminase (TGase-4, TGaseP) regulates the interaction of prostate cancer and vascular endothelial cells, a potential role for the ROCK pathway. Microvascular Research 77(2), pp. 150-157. (10.1016/j.mvr.2008.09.010)
Al Sarakbi, W., Sasi, W., Jiang, W. G., Roberts, T., Newbold, R. F. and Mokbel, K. 2009. The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters. BMC Cancer 9, pp. 290-296. (10.1186/1471-2407-9-290)
Patani, N., Jiang, W. G., Mansel, R. E., Newbold, R. and Mokbel, K. 2009. The mRNA expression of SATB1 and SATB2 in human breast cancer. Cancer Cell International 9, pp. 18-27. (10.1186/1475-2867-9-18)
Chen, J., Ye, L., Zhang, L. and Jiang, W. G. 2009. The molecular impact of pigment epithelium-derived factor, PEDF, on lung cancer cells and the clinical significance. International Journal of Oncology 35(1), pp. 159-166. (10.3892/ijo_00000324)
Li, J., Ye, L., Parr, C., Douglas-Jones, A., Kynaston, H. G., Mansel, R. E. and Jiang, W. G. 2009. The aberrant expression of bone morphogenetic protein 12 (BMP-12) in human breast cancer and its potential prognostic value. Gene Therapy and Molecular Biology 13A, pp. 186-193.

2008

Lane, J., Martin, T. A., Mansel, R. E. and Jiang, W. G. 2008. The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer. International Seminars in Surgical Oncology 5(1), article number: 23. (10.1186/1477-7800-5-23)
Chen, L., Wei, X., Evans, B. A. J., Jiang, W. G. and Aeschlimann, D. 2008. IL-23 promotes osteoclast formation by up-regulation of receptor activator of NF-kappa B (RANK) expression in myeloid precursor cells. European Journal of Immunology 38(10), pp. 2845-2854. (10.1002/eji.200838192)
Jiang, W. G., Martin, T. A., Lewis-Russell, J. M., Douglas-Jones, A. G., Ye, L. and Mansel, R. E. 2008. Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome. Molecular Cancer 7, article number: 71. (10.1186/1476-4598-7-71)
Martin, T. A., Harrison, G. M., Watkins, G. and Jiang, W. G. 2008. Claudin-16 reduces the aggressive behavior of human breast cancer cells. Journal of Cellular Biochemistry 105(1), pp. 41-52. (10.1002/jcb.21797)
Chen, J., Ye, L., Zhang, L. and Jiang, W. G. 2008. Placenta growth factor, PLGF, influences the motility of lung cancer cells, the role of Rho associated kinase, Rock1. Journal of Cellular Biochemistry 105(1), pp. 313-320. (10.1002/jcb.21831)
Sanders, A. J., Parr, C., Martin, T. A., Lane, J., Mason, M. D. and Jiang, W. G. 2008. Genetic upregulation of matriptase-2 reduces the aggressiveness of prostate cancer cells in vitro and in vivo and affects FAK and paxillin localisation. Journal of Cellular Physiology 216(3), pp. 780-789. (10.1002/jcp.21460)
Salhab, M., Jiang, W. G., Newbold, R. and Mokbel, K. 2008. The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinico-pathological parameters and clinical outcome. Breast Cancer Research and Treatment 109(1), pp. 35-46. (10.1007/s10549-007-9622-8)
Sun, J., Watkins, G., Blair, A. L., Moskaluk, C., Ghosh, S., Jiang, W. G. and Li, R. 2008. Deregulation of cofactor of BRCA1 expression in breast cancer cells. Journal of Cellular Biochemistry 103(6), pp. 1798-1807. (10.1002/jcb.21568)
Subramanian, A., Chong, Y. M., Das, R., Mokbel, K., Colston, K., Jiang, W. G. and Sharma, A. K. 2008. Insulin like binding protein 7 - evidence for a possible paracrine protective effect in human breast cancer. EJC Supplements 6(7), pp. 80-80.
Davies, S., Dent, C. M., Watkins, G., King, J. A., Mokbel, K. and Jiang, W. G. 2008. Expression of the cell to cell adhesion molecule, ALCAM, in breast cancer patients and the potential link with skeletal metastasis. Oncology Reports 19(2), pp. 555-561.
Lane, J., Martin, T. A., Watkins, G., Mansel, R. E. and Jiang, W. G. 2008. The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer. International Journal of Oncology 33(3), pp. 585-593. (10.3892/ijo_00000044)
Fernando, H., Sanders, A. J., Jenkins, S., Kynaston, H. and Jiang, W. G. 2008. Wave 3 (Wasp Verprolin-Homologous Protein) 3 is involved in the invasiveness of PC-3 cells [Abstract]. European Urology Supplements 7(3), pp. 173. (10.1016/S1569-9056(08)60406-6)
King, J. A., Shevde, L. A., Ofori-Acquah, S., Watkins, G. and Jiang, W. G. 2008. Is N-cadherin expression important in ductal carcinoma?. Southern Medical Journal 101(5), pp. 470-475. (10.1097/SMJ.0b013e31816c0112)
Worku, D., Jouhra, F., Jiang, W. G., Patani, N., Newbold, R. F. and Mokbel, K. 2008. Evidence of a tumour suppressive function of E2F1 gene in human breast cancer. Anticancer Research 28(4B), pp. 2135-2139.
Clark, D. W., Mitra, A., Fillmore, R. A., Jiang, W. G., Samant, R. S., Fodstad, O. and Shevde, L. A. 2008. NUPR1 interacts with p53, transcriptionally regulates p21 and rescues breast epithelial cells from doxorubicin-induced genotoxic stress. Current Cancer Drug Targets 8(5), pp. 421-430.
Davies, S., Mansel, R. E. and Jiang, W. G. 2008. Osteocalcin as a prognostic indicator for bone metastasis in ductal breast cancer [Abstract]. Calcified Tissue International 83(1), pp. 27. (10.1007/s00223-008-9151-4)
Davies, S., Mansel, R. E. and Jiang, W. G. 2008. Osteoprotegrin as a prognostic indicator for bone metastasis in ductal breast cancer [Abstract]. Calcified Tissue International 83(1), pp. 6. (10.1007/s00223-008-9151-4)
Patani, N., Jouhra, F., Jiang, W. G. and Mokbel, K. 2008. Osteopontin expression profiles predict pathological and clinical outcome in breast cancer. Anticancer Research 28(6B), pp. 4105-4110.
Patani, N., Jiang, W. G. and Mokbel, K. 2008. Osteopontin C mRNA expression is associated with a poor clinical outcome in human breast cancer [Letter to the Editor]. International Journal of Cancer 122(11), pp. 2646. (10.1002/ijc.23402)
Fernando, H. S., Sanders, A. J., Kynaston, H. and Jiang, W. G. 2008. WAVE1 is Associated with Invasiveness and Growth of Prostate Cancer Cells. The Journal of Urology 180(4), pp. 1515-1521. (10.1016/j.juro.2008.06.004)
Ye, L., Lewis-Russell, J. M., Sanders, A. J., Kynaston, H. G. and Jiang, W. G. 2008. HGF/SF up-regulates the expression of bone morphogenetic protein 7 in prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 26(2), pp. 190-197. (10.1016/j.urolonc.2007.03.027)
Davies, G., Martin, T. A., Ye, L., Lewis-Russell, J. M., Mason, M. D. and Jiang, W. G. 2008. Phospholipase-C gamma-1 (PLCγ-1) is critical in hepatocyte growth factor induced in vitro invasion and migration without affecting the growth of prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 26(4), pp. 386-391. (10.1016/j.urolonc.2007.06.003)
Davies, G., Jiang, W. G. and Mason, M. D. 2008. Hepatocyte growth factor/scatter factor and prostate cancer metastasis. In: Ablin, R. J. and Mason, M. D. eds. Metastasis of prostate cancer. Cancer Metastasis Vol. 10. Dordrecht: Springer, pp. 197-220.
Jiang, W. G. 2008. Polyunsaturated fatty acids and prostate cancer metastasis. In: Ablin, R. J. and Mason, M. D. eds. Metastasis of prostate cancer. Cancer metastasis - biology and treatment Vol. 10. Dordrecht: Springer, pp. 63-86.
Ye, L., Kynaston, H. and Jiang, W. G. 2008. Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4. Molecular Cancer Research 6(10), pp. 1594-1606. (10.1158/1541-7786.MCR-08-0171)
Goyal, A., Martin, T. A., Mansel, R. E. and Jiang, W. G. 2008. Real time PCR analyses of expression of E-cadherin, alpha-, beta- and gamma-catenin in human breast cancer for predicting clinical outcome. World Journal of Surgical Oncology 6, pp. 56-61. (10.1186/1477-7819-6-56)
Malik, F. A., Kayani, M. A., Iqbal, H., Jiang, W. G. and Sadiq, R. 2008. Screening of coding region of metastasis suppressor genes KISS1 and KAI-1 for germ line mutations in breast cancer patients. Gene Therapy and Molecular Biology 12B, pp. 239-246.

2007

Salhob, M., Jiang, W. G., Newhold, R. F. and Mokhel, K. 2007. The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinicopathological parameters and clinical outcome. Breast Cancer Research and Treatment 106, pp. S283-S283.
Davies, S. R., Mansel, R. E. and Jiang, W. G. 2007. The potential prognostic value of osteoprotegrin in ductal carcinoma of the breast. Breast Cancer Research and Treatment 106, pp. S172-S172.
Davies, S. R., Mansel, R. E. and Jiang, W. G. 2007. Osteocalcin as a prognostic indicator in ductal mammary carcinoma. Breast Cancer Research and Treatment 106, pp. S164-S164.
Sun, J., Watkins, G., Amleh, A., Jiang, W. G. and Li, R. 2007. Dysregulation of cofactor of BRCA1 expression in breast cancers. Breast Cancer Research and Treatment 106, pp. S282-S282.
Zia, M. K., Rmali, K. A., Watkins, G., Mansel, R. E. and Jiang, W. G. 2007. The expression of the von Hippel-Lindau gene product and its impact on invasiveness of human breast cancer cells. International Journal of Molecular Medicine 20(4), pp. 605-611. (10.3892/ijmm.20.4.605)
Chhabra, A., Fernando, H., Watkins, G., Mansel, R. E. and Jiang, W. G. 2007. Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis. Oncology Reports 18(4), pp. 953-958.
Sanders, A. J., Parr, C., Mason, M. D. and Jiang, W. G. 2007. Suppression of hepatocyte growth factor activator inhibitor-1 leads to a more aggressive phenotype of prostate cancer cells in vitro. International Journal of Molecular Medicine 20(4), pp. 613-619.
Subramanian, A., Sharma, A. K., Banerjee, D., Jiang, W. G. and Mokbel, K. 2007. Evidence for a tumour suppressive function of IGFI-binding proteins in human breast cancer. Anticancer Research 27(5B), pp. 3513-3518.
Parr, C. et al. 2007. Matriptase-2 inhibits breast tumor growth and invasion and correlates with favorable prognosis for breast cancer patients. Clinical Cancer Research 13(12), pp. 3568-3576. (10.1158/1078-0432.CCR-06-2357)
Conway, K. P., Price, P. E., Harding, K. G. and Jiang, W. G. 2007. The role of vascular endothelial growth inhibitor in wound healing. International Wound Journal 4(1), pp. 55-64. (10.1111/j.1742-481X.2006.00295.x)
Martin, T. A., Pereira, G., Watkins, G., Mansel, R. E. and Jiang, W. G. 2007. N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer. Clinical & Experimental Metastasis 25(2), pp. 97-108. (10.1007/s10585-007-9120-8)
Conway, K. P., Ruge, F., Price, P. E., Harding, K. G. and Jiang, W. G. 2007. Hepatocyte growth factor regulation: an integral part of why wounds become chronic. Wound Repair and Regeneration 15(5), pp. 683-692. (10.1111/j.1524-475X.2007.00296.x)
Al-Rawi, M. A. and Jiang, W. G. 2007. Lymphangiogenesis and metastatic spread of breast cancer. In: Mansel, R. E., Fodstad, O. and Jiang, W. G. eds. Metastasis of Breast Cancer. Cancer Metastasis, Biology and Treatment (CMBT) Vol. 11. Dordrecht: Springer, pp. 219-240., (10.1007/978-1-4020-5867-7)
Mansel, R. E., Fodstad, O. and Jiang, W. G. 2007. Metastasis of breast cancer: an introduction. In: Mansel, R. E., Fodstad, O. and Jiang, W. G. eds. Metastasis of Breast Cancer. Cancer Metastasis - Biology and Treatment (CMBT) Vol. 11. Dordrecht: Springer, pp. 1-5., (10.1007/978-1-4020-5867-7_1)
Parr, C. and Jiang, W. G. 2007. The role of the HGF regulatory factors in breast cancer. In: Mansel, R. E., Fodstad, O. and Jiang, W. G. eds. Metastasis of Breast Cancer. Cancer Metastasis, Biology and Treatment (CMBT) Vol. 11. Dordrecht: Springer, pp. 171-202.
Fernando, H. S. et al. 2007. Expression of the WASP verprolin-homologues (WAVE members) in human breast cancer. Oncology 73(5-6), pp. 376-383.

2006

Lane, J., Martin, T. A. and Jiang, W. G. 2006. Novel protein binding partners for Rho-associated serine-threonine protein kinases (ROCKS) in breast cancer cells [Abstract]. Breast Cancer Research and Treatment 100(1 Supp), pp. S298-S298., article number: 6127.
Hiscox, S. E., Jordan, N. J., Jiang, W. G., Harper, M. E., McClelland, R., Smith, C. and Nicholson, R. 2006. Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: implications for tumour-stroma interactions. Endocrine-Related Cancer 13(4), pp. 1085-1099. (10.1677/erc.1.01270)
Jiang, W. G., Davies, G., Martin, T. A., Kynaston, H., Mason, M. D. and Fodstad, O. 2006. Com-1/p8 acts as a putative tumour suppressor in prostate cancer. International Journal of Molecular Medicine 18(5), pp. 981-986.
Salhab, M., Reed, M. J., Al Sarakbi, W., Jiang, W. g. and Mokbel, K. 2006. The role of aromatase and 17-beta-hydroxysteroid dehydrogenase type 1 mRNA expression in predicting the clinical outcome of human breast cancer. Breast Cancer Research and Treatment 99(2), pp. 155-162.
Cai, J., Parr, C., Watkins, G., Jiang, W. G. and Boulton, M. E. 2006. Decreased pigment epithelium-derived factor expression in human breast cancer progression. Clinical Cancer Research 12(11), pp. 3510-3517. (10.1158/1078-0432.CCR-06-0094)
Hanavadi, S., Martin, T. A., Watkins, G., Mansel, R. E. and Jiang, W. G. 2006. Expression of interleukin 11 and its receptor and their prognostic value in human breast cancer. Annals of Surgical Oncology 13(6), pp. 802-808.
Zhang, L. J., Chen, J. F. ., Ke, Y., Mansel, R. E. and Jiang, W. G. 2006. Expression of pigment epithelial derived factor is reduced in non-small cell lung cancer and is linked to clinical outcome. International Journal of Molecular Medicine 17(5), pp. 937-944.
Jiang, W. G., Davies, G., Martin, T. A., Parr, C., Watkins, G., Mason, M. D. and Mansel, R. E. 2006. Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells. International Journal of Molecular Medicine 17(4), pp. 583-590.
Jiang, W. G., Douglas-Jones, A. G. and Mansel, R. E. 2006. Aberrant expression of 5-lipoxygenase-activating protein (5-LOXAP) has prognostic and survival significance in patients with breast cancer. Prostaglandins Leukotrienes & Essential Fatty Acids 74(2), pp. 125-134.
Hiscox, S. E. et al. 2006. Tamoxifen-resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of [beta]-catenin phosphorylation. International journal of cancer 118(2), pp. 290-301. (10.1002/ijc.21355)
Harrison, G., Davies, G., Martin, T. A., Mason, M. D. and Jiang, W. G. 2006. The influence of CD44v3-v10 on adhesion, invasion and MMP-14 expression in prostate cancer cells. Oncology Reports 15(1), pp. 199-206. (10.3892/or.15.1.199)
Congiatu, C., Brancale, A., Mason, M. D., Jiang, W. G. and McGuigan, C. 2006. Novel potential anticancer naphthyl phosphoramidates of BVdU: Separation of diastereoisomers and assignment of the absolute cConfiguration of the phosphorus center. Journal of Medicinal Chemistry 49(2), pp. 452-455. (10.1021/jm0509896)
Conway, K. P., Price, P. E., Harding, K. G. and Jiang, W. G. 2006. The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing. Wound Repair and Regeneration 14(1), pp. 2-10. (10.1111/j.1743-6109.2005.00081.x)
Jiang, W. G., Davies, G., Ye, L., Russell-Lewis, J., Mason, M. D. and Mansel, R. E. 2006. EPLIN (epithelial protein lost in neoplasm) affects matrix adhesion and cellular motility of breast cancer cells, the role of ezrin [Abstract]. Breast Cancer Research and Treatment 100, pp. S161-S161.
Sanders, A. J., Parr, C., Davies, G., Martin, T. A., Lane, J., Mason, M. D. and Jiang, W. G. 2006. Genetic reduction of matriptase-1 expressionj is associated with a reduction in the aggressive phenotype of prostate cancer cells in vitro and in vivo. Journal of Experimental Therapeautics and Oncology 6(1), pp. 39-48.
Sanders, A. J., Parr, C., Davies, G., Martin, T. A., Lane, J., Mason, M. D. and Jiang, W. G. 2006. Genetic reduction of matriptase-1 expression is associated with a reduction in the aggressive phenotype of prostate cancer cells in vitro and in vivo. Journal of Experimental Therapeutics and Oncology 6(1), pp. 39-48.

2005

Jiang, W. G., Watkins, G., Douglas-Jones, A. G., Mokbel, K., Mansel, R. E. and Fodstad, O. 2005. Expression of Com-1/P8 in human breast cancer and its relevance to clinical outcome and ER status. International Journal of Cancer 117(5), pp. 730-737. (10.1002/ijc.21221)
Cai, J., Jiang, W. G., Grant, M. B. and Boulton, M. E. 2005. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of Vascular Endothelial Growth Factor Receptor 1. The Journal of Biological Chemistry 281(6), pp. 3604-3613. (10.1074/jbc.M507401200)
Lane, J., Martin, T. and Jiang, W. G. 2005. Targeting Rho-C by way of ribozyme transgene in human breast cancer cells and its impact on cancer invasion. Breast Cancer Research and Treatment 94(1), pp. S188-S189., article number: 4068. (10.1007/s10549-005-1234-6)
Lane, J., Martin, T. A. and Jiang, W. G. 2005. ROCK inhibitor Y-27632 suppresses the effect of HGF in human breast cancer cells [Abstract]. Breast Cancer Research and Treatment 94(1 Supp), pp. S193-S194., article number: 4082.
Parr, C., Watkins, G., Boulton, M., Cai, J. and Jiang, W. G. 2005. Placenta growth factor is over-expressed and has prognostic value in human breast cancer. European Journal of Cancer 41(18), pp. 2819-2827.
Martin, T. A., Watkins, G. and Jiang, W. G. 2005. KiSS-1 expression in human breast cancer. Clinical & Experimental Metastasis 22(6), pp. 503-511.
Kang, H., Watkins, G., Douglas-Jones, A., Mansel, R. E. and Jiang, W. G. 2005. The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer. The Breast 14(5), pp. 360-367. (10.1016/j.breast.2004.12.007)
Martin, T. A., Watkins, G. and Jiang, W. G. 2005. The Coxsackie-adenovirus receptor has elevated expression in human breast cancer. Clinical and Experimental Medicine 5(3), pp. 122-128.
Leris, A. C. A., Roberts, T. R., Jiang, W. G., Newbold, R. F. and Mokbel, K. 2005. Evidence for a tumour suppressive function of APRG1 in breast cancer. Breast Cancer Research and Treatment 93(2), pp. 97-100.
Jiang, W. G. et al. 2005. Targeting matrilysin and its impact on tumor growth in vivo: the potential implications in breast cancer therapy. Clinical Cancer Research 11(16), pp. 6012-6019. (10.1158/1078-0432.CCR-05-0275)
Jiang, W. G. et al. 2005. Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: The role of promoter methylation of TSC genes. European Journal of Cancer 41(11), pp. 1628-1636. (10.1016/j.ejca.2005.03.023)
Hawizy, A., Davies, G., Harrison, G. M., Kynaston, H., Mason, M. D. and Jiang, W. G. 2005. Differential expression of Wnt-induced secreted proteins (WISPs) in prostate tissues and cancer cell lines and their role in the action of HGF/SF induced in vitro invasion. Bju International 95, pp. 81-82.
Conway, K., Price, P., Harding, K. G. and Jiang, W. G. 2005. Is the hepatocyte growth factor regulatory system the reason for wounds becoming chronic?. British Journal of Surgery 92, pp. 45-45.
Martin, T. A., Watkins, G., Lane, J. and Jiang, W. G. 2005. Assessing microvessels and angiogenesis in human breast cancer, using VE-cadherin. Histopathology 46(4), pp. 422-430. (10.1111/j.1365-2559.2005.02104.x)
Leris, A. C. A., Roberts, T. R., Jiang, W. G., Newbold, R. F. and Mokbel, K. 2005. WNT5A expression in human breast cancer. Anticancer Research 25(2A), pp. 731-734.
Hiscox, S. E., Harper, M. E., Jiang, W. G., McClelland, R. and Nicholson, R. 2005. Elevated c-met expression accompanies endocrine resistance in MCF7 breast cancer cells and promotes in vitro cell migration and invasion. Breast Cancer Research and Treatment 94(Supp 1), pp. S161-S161.
Martin, T. A., Goyal, A., Watkins, G. and Jiang, W. G. 2005. Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Annals of Surgical Oncology 12(6), pp. 488-496. (10.1245/ASO.2005.04.010)
Parr, C., Watkins, G. and Jiang, W. G. 2005. Hepsin expression is inversely correlated with patient prognosis in human breast cancer. Breast Cancer Research and Treatment 94, pp. S137-S137.
Lane, J., Martin, T. A. and Jiang, W. G. 2005. The ROCK Inhibitor Y-27632 supresses the effect of HGF in human breast cancer cells. Breast Cancer Research and Treatment 94, pp. S193-S194.
Parr, C., Gan, C., Harrison, G. and Jiang, W. G. 2005. Vascular endothelial growth inhibitor (VEGI), an antiangiogenic factor, in human breast cancer. Breast Cancer Research and Treatment 94, pp. S74-S74.
Jiang, W., Martin, T., Douglas-Jones, A. and Mansel, R. 2005. EPLIN, epithelial protein lost in neoplasm, is aberrantly expressed in human breast cancer and is related to clinical outcomes. Breast Cancer Research and Treatment 94(Supp 1), pp. S184.
Jiang, W., Davies, G., Martin, T. A., Parr, C., Mason, M. D. and Mansel, R. E. 2005. Manipulation of expression of MMP-14 and its impact on the invasivess and progression of breast cancer cells [Abstract]. Breast Cancer Research and Treatment 94, pp. S187-S187.
Jiang, W. G., Davies, G., Watkins, G., Mason, M. D. and Mansel, R. E. 2005. Autophophorylation of the hepatocyte growth factor receptor, cMET in human breast cancer. Breast Cancer Research and Treatment 94, pp. S192-S192.

2004

Jiang, W. G., Watkins, G., Fodstad, O., Douglas-Jones, A. G., Mokbel, K. and Mansel, R. E. 2004. Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer. Endocrine Related Cancer 11(4), pp. 781-791. (10.1677/erc.1.00825)

2003

Jiang, W. G., Watkins, G., Lane, J., Cunnick, G. H., Douglas-Jones, A. G., Mokbel, K. and Mansel, R. E. 2003. Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Clinical cancer research 9, pp. 6432-40.
Cai, J., Ahmad, S., Jiang, W. G., Huang, J., Kontos, C. D., Boulton, M. E. and Ahmed, A. 2003. Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells. Diabetes 52(12), pp. 2959-2968. (10.2337/diabetes.52.12.2959)
Jiang, W. G. et al. 2003. Reduction of stromal fibroblast-induced mammary tumor growth, by retroviral ribozyme transgenes to hepatocyte growth factor/scatter factor and its receptor, c-MET. Clinical Cancer Research 9(11), pp. 4274-4281.
Davies, G. et al. 2003. The HGF/SF antagonist NK4 reverses fibroblast- and HGF-induced prostate tumor growth and angiogenesisin vivo. International Journal of Cancer 106(3), pp. 348-354. (10.1002/ijc.11220)
Lane, J., Mansel, R. E. and Jiang, W. G. 2003. Expression of human delta-6-desaturase is associated with aggressiveness of human breast cancer. International Journal of Molecular Medicine 12(2), pp. 253-257. (10.3892/ijmm.12.2.253)
Al-Rawi, M. A. A., Mansel, R. E. and Jiang, W. G. 2003. Interleukin-7 (IL-7) and IL-7 receptor (IL-7R) signalling complex in human solid tumours. Histology and Histopathology 18(3), pp. 911-923.
Martin, T. A. et al. 2003. Growth and angiogenesis of human breast cancer in a nude mouse tumour model is reduced by NK4, a HGF/SF antagonist. Carcinogenesis 24(8), pp. 1317-1323. (10.1093/carcin/bgg072)
Cai, J., Boulton, M. E., Jiang, W. G. and Ahmed, A. 2003. Placenta growth factor upregulates VE-cadherin expression in microvascular endothelial cells. Investigative Ophthalmology & Visual Science 44(E-Abst)

2002

Gomez, K., Lane, J., Cunnick, G., Grimshaw, D., Jiang, W. G. and Mansel, R. E. 2002. From PCR to RCA: a surgical trainee's guide to the techniques of genetic amplification. European Journal of Surgical Oncology (EJSO) 28(5), pp. 554-556. (10.1053/ejso.2002.1288)
Kim, N. D. et al. 2002. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Research and Treatment 71(3), pp. 203-217.
Boulton, M. E., Cai, J., Jiang, W. G. and Ahmed, A. 2002. Role of placenta growth factor (PIGF) and PIGF/VEGF heterodimer in the regulation of in vitro angiogenesis. Investigative Ophthalmology & Visual Science 43(E-Abst)

2001

Cunnick, G., Jiang, W. G., Gomez, K. and Mansel, R. E. 2001. Lymphangiogenesis quantification using quantitative PCR and breast cancer as a model. Biochemical and Biophysical Research Communications 288(4), pp. 1043-1046. (10.1006/bbrc.2001.5869)
Parr, C. and Jiang, W. G. 2001. Expression of hepatocyte growth factor/scatter factor, its activator, inhibitors and the c-Met receptor in human cancer cells. International Journal of Oncology 19, pp. 857-863. (10.3892/ijo.19.4.857)
Davies, G., Jiang, W. G. and Davies, M. D. 2001. Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells: a key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion. Clinical Cancer Research 7, pp. 3289-3297.
Parr, C., Davies, G., Nakamura, T., Matsumoto, K., Mason, M. D. and Jiang, W. G. 2001. The HGF/SF-induced phosphorylation of paxillin, matrix adhesion, and invasion of prostate cancer cells were suppressed by NK4, an HGF/SF variant.. Biochemical and Biophysical Research Communications 285(5), pp. 1330-1337. (10.1006/bbrc.2001.5307)
Jiang, W. G., Grimshaw, A. D., Lane, J., Martin, T. A., Abounader, R., Laterra, J. and Mansel, R. E. 2001. A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-MET and reduces migration and invasiveness of breast cancer cells. Clinical Cancer Research 7, pp. 2555-2562.
Parr, C., Davies, G., Hiscox, S. E., Nakamura, T., Matsumoto, K., Jiang, W. G. and Mansel, R. E. 2001. Inhibition of HGF/SF-induced cell-matrix adhesion, invasion, migration & paxillin phosphorylation, in prostate cancer by the HGF/SF antagonist, NK4. British Journal of Cancer 85(Supp 1), pp. 86-86. (10.1054/bjoc.2001.1918)
Davies, G., Jiang, W. G. and Mason, M. D. 2001. HGF/SF modifies the interaction between its receptor c-Met, and the E-cadherin/catenin complex in prostate cancer cells.. International Journal of Molecular Medicine 7, pp. 385-388. (10.3892/ijmm.7.4.385)
Davies, G., Jiang, W. G. and Mason, M. D. 2001. The interaction between beta-catenin, GSK3beta and APC after motogen induced cell-cell dissociation, and their involvement in signal transduction pathways in prostate cancer.. International Journal of Oncology 18(4), pp. 843-847. (10.3892/ijo.18.4.843)
Martin, T. A., Mansel, R. E. and Jiang, W. G. 2001. Hepatocyte growth factor modulates vascular endothelial-cadherin expresssion in human endothelial cells. Clinical Cancer Research 7(3), pp. 734-737.
Stephens, P., Hiscox, S. E., Cook, H., Jiang, W. G., Zhiquiang, W. and Thomas, D. W. 2001. Phenotypic variation in the production of bioactive hepatocyte growth factor/scatter factor by oral mucosal and skin fibroblasts. Wound Repair and Regeneration 9(1), pp. 34-43. (10.1046/j.1524-475x.2001.00034.x)
Parr, C. and Jiang, W. G. 2001. Hepatocyte growth factor activators, inhibitors and antagonists and their implication in cancer intervention.. Histology and Histopathology 16(1), pp. 251-268.
Martin, T. A. and Jiang, W. G. 2001. Tight junctions and their role in cancer metastasis.. Histology and Histopathology 16, pp. 1183-1195.
Martin, T. A., Harding, K. G. and Jiang, W. G. 2001. Matrix-bound fibroblasts regulate angiogenesis by modulation of VE-cadherin. European Journal of Clinical Investigation 31(11), pp. 931-938. (10.1046/j.1365-2362.2001.00914.x)

2000

Jiang, W. G., Eynard, A. R. and Mansel, R. E. 2000. The pathology of essential fatty acid deficiency: is it cell adhesion mediated?. Medical Hypothesis 55, pp. 257-262. (10.1054/mehy.1998.1191)
Davies, G., Jiang, W. G. and Mason, M. D. 2000. Cell-cell adhesion molecules and signaling intermediates and their role in the invasive potential of prostate cancer cells.. Journal of Urology 163(3), pp. 985-992.
Parr, C., Hiscox, S. E., Nakamura, T., Matumoto, K. and Jiang, W. G. 2000. NK4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells. International Journal of Cancer 85(4), pp. 563-570. (10.1002/(SICI)1097-0215(20000215)85:4<563::AID-IJC19>3.0.CO;2-D)
Hiscox, S. E., Parr, C., Nakamura, T., Matsumoto, K., Jiang, W. G. and Mansel, R. E. 2000. Inhibition of HGF/SF-induced breast cancer cell motility and invasion by the HGF/SF variant, NK4. British Journal of Cancer 59(3), pp. 245-254. (10.1023/A:1006348317841)
Jiang, W. G., Redfern, A. J., Bryce, R. P. and Mansel, R. E. 2000. Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells.. Prostaglandins Leukotrienes & Essential Fatty Acids 62(2), pp. 119-127. (10.1054/plef.1999.0131)
Jiang, W. G. and Mansel, R. E. 2000. Metastatic cascade, molecular/cellular events. In: Jiang, W. G. and Mansel, R. E. eds. Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention. Cancer Metastasis - Biology and Treatment Vol. 1. Dordrecht, Netherlands: Kluwer Academic Publishers, pp. 1-18.
Jiang, W. G., Redfern, A., Eynard, A. and Mansel, R. E. 2000. Polyunsaturated fatty acids and their role in cancer invasion and metastasis. In: Jiang, W. G. and Mansel, R. E. eds. Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention. Cancer Metastasis - Biology and Treatment Vol. 1. Dordrecht, Netherlands: Kluwer Academic Publishers, pp. 225-253.
Jiang, W. G., Martin, T. and Mansel, R. E. 2000. Tight junction, a critical structure in the control of cancer invasion and metastasis. In: Jiang, W. G. and Mansel, R. E. eds. Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention. Cancer Metastasis - Biology and Treatment Vol. 1. Dordrecht, Netherlands: Kluwer Academic Publishers, pp. 195-214.
Hoppe, A., Wertheim, D., Jiang, W. G., Williams, R. and Harding, K. 2000. Interactive image processing system for assessment of cell movement.. Medical and Biological Engineering and Computing 37(4), pp. 419-423.
Jiang, W. G. and Mansel, R. E. 2000. E-cadherin complex and its abnormalities in human breast cancer. Surgical Oncology 9, pp. 151-171.

1999

Jiang, W. G., Hiscox, S. E., Parr, C., Martin, T. A., Matsumoto, K., Nakamura, T. and Mansel, R. E. 1999. Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells. Clinical Cancer Research 5(11), pp. 3695-3703.
Jiang, W. G., Martin, T. A., Matsumoto, K., Nakamur, T. and Mansel, R. E. 1999. Hepatocyte growth factor/scatter factor decreases the expression of occludin and transendothelial resistance (TER) and increases paracellular permeability in human vascular endothelial cells.. Journal of Cellular Physiology 181(2), pp. 219-329. (10.1002/(SICI)1097-4652(199911)181:2<319::AID-JCP14>3.0.CO;2-S)
Hiscox, S. E., Mansel, R. E. and Jiang, W. G. 1999. Ezrin regulates cell-cell adhesion and motility and associates with intercellular junctional proteins in cancer cells. British Journal of Cancer 81(4), pp. 579-579. (10.1038/sj.bjc.6690733)
Hiscox, S. E. and Jiang, W. G. 1999. Ezrin regulates cell-cell and cell-matrix adhesion, a possible role with E-cadherin/beta-catenin. Journal of Cell Science 112(18), pp. 3081-3090.
Hiscox, S. E. and Jiang, W. G. 1999. Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cells. Biochemical and Biophysical Research Communications 261(2), pp. 406-411. (10.1006/bbrc.1999.1002)
Cai, J., Jiang, W. and Mansel, R. 1999. Phosphorylation and disorganization of vascular-endothelial cadherin in interaction between breast cancer and vascular endothelial cells. International Journal of Molecular Medicine 4(2), pp. 191-195. (10.3892/ijmm.4.2.191)
Davies, E. L., Gee, J. M. W., Cochrane, R. A., Jiang, W. G., Sharma, A. K., Nicholson, R. I. and Mansel, R. E. 1999. The immunohistochemical expression of desmoplakin and its role in vivo in the progression and metastasis of breast cancer. European Journal of Cancer 35(6), pp. 902-907. (10.1016/S0959-8049(99)00031-3)
Cai, J., Jiang, W. and Mansel, R. 1999. Inhibition of the expression of VE-cadherin/catenin complex by gamma linolenic acid in human vascular endothelial cells, and its impact on angiogenesis. Biochemical and Biophysical Research Communications 258(1), pp. 113-118. (10.1006/bbrc.1999.0596)
Jiang, W. G., Hiscox, S., Matsumoto, K. and Nakamura, T. 1999. Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer. Critical Reviews in Oncology/Hematology 29(3), pp. 209-248.
Hiscox, S. E. and Jiang, W. G. 1999. Hepatocyte growth factor scatter factor disrupts epithelial tumour cell-cell adhesion: involvement of beta-catenin. Anticancer Research 19(1A), pp. 509-517.
Cai, J., Jiang, W. and Mansel, R. 1999. Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. Prostaglandins Leukotrienes & Essential Fatty Acids 60(1), pp. 21-29. (10.1054/plef.1998.0004)
Davies, G., Jiang, W. G. and Mason, M. D. 1999. Cell-cell adhesion molecules and their associated proteins in bladder cancer cells and their role in mitogen induced cell-cell dissociation and invasion.. Anticancer Research 19(1A), pp. 547-552.
Davies, G., Hiscox, S. E., Llaffafian, I., Jiang, W. G. and Mason, M. D. 1999. HGF/SF influences the interaction between APC, GSK3 beta and beta-catenin, its impact on cell adhesion and in vitro invasion in prostate cancer. British Journal of Cancer 80(Supp 2), pp. 36-36.

1998

Eynard, A. R., Jiang, W. G. and Mansel, R. E. 1998. Eicosatrienoic acid (20:3 n-9) inhibits the expression of E-cadherin and desmoglein in human squamous cell carcinoma in vitro.. Prostagladins Leukotrienes and Essential Fatty Acids 59(6), pp. 371-377. (10.1016/S0952-3278(98)90098-9)
Davies, G., Jiang, W. G. and Mason, M. D. 1998. E-cadherin and associated molecules in the invasion and progression of prostate cancer. Oncology Reports 5(6), pp. 1567-1576. (10.3892/or.5.6.1567)
Jiang, W. G., Bryce, R. P., Horrobin, D. F. and Mansel, R. E. 1998. gamma-Linolenic acid blocks cell cycle progression by regulating phosphorylation of p27kip1 and p57kip2 and their interactions with other cycle regulators in cancer cells.. International Journal of Oncology 13(3), pp. 611-617.
Davies, E. L., Gee, J. M. W., Cochrane, R. A., Nicholson, R. I., Sharma, A. K., Jiang, W. G. and Mansel, R. E. 1998. The expression of desmoglein-2 in primary breast cancer and its relation to a series of prognostic markers [Abstract]. British Journal of Cancer 78(2), pp. 149. (10.1038/bjc.1998.457)
Hiscox, S. E., Davies, E. and Jiang, W. G. 1998. Up-regulation of the expression of hepatocyte growth factor activator (HGFA) in breast cancer. British Journal of Cancer 78(2), pp. 150-150. (10.1038/bjc.1998.457)
Jiang, W. G., Hiscox, S. E., Bryce, R. P., Horrobin, D. F. and Mansel, R. E. 1998. The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells. British Journal of Cancer 77(5), pp. 731-738. (10.1038/bjc.1998.120)
Cai, J., Jiang, W. and Mansel, R. 1998. Gap junctional communication and the tyrosine phosphorylation of connexin 43 in interaction between breast cancer and endothelial cells. International Journal of Molecular Medicine 1(1), pp. 273-278. (10.3892/ijmm.1.1.273)
Jiang, W. G., Hiscox, S. E., Horrobin, D. F., Bryce, R. P. and Mansel, R. E. 1998. Essential fatty acids regulate the expression of tumour suppressor genes in cancer cells. Presented at: Fourth International Congress on Essential Fatty Acids and Eicosanoids, Edinburgh, UK, 20-24 July 1997 Presented at Riemersma, R. A. et al. eds.Essential fatty acids and eicosanoids: invited papers from the Fourth International Congress. Champaign, Illinois: AOCS Press pp. 303-311.
Eynard, A. R., Jiang, W. G. and Mansel, R. E. 1998. Eicosatrienoic acid (20:3, n-9) regulate the expression of E-cadherin and desmoglein in squamous cell carcinoma. Presented at: 17th International Cancer Congress, Rio de Janeiro, Brazil, 24-28 August 1998 Presented at Moraes, M., Brentani, R. and Bevilacqua, R. eds.Proceedings of the 17th International Cancer Congress. Bologna: Medimond pp. 233-238.
Jiang, W. G. and Bryce, R. P. 1998. Essential fatty acids: molecular and cellular basis of their anti-cancer action and clinical implications. Critical Reviews in Oncology/Hematology 27, pp. 179-209.
Hoppe, A. and Jiang, W. G. 1998. A system for computer analysis of cancer cell movement. Anticancer Research 18, pp. 2691-2694.
Jiang, W. G. and Hiscox, S. 1998. Association of PTPmu with catenins in cancer cells: a possible role for E-cadherin. International Journal of Oncology 13, pp. 1077-1080.
Jiang, W. G. 1998. Regulation of cell adhesion, a central mechanism in the anticancer action of essential fatty acids. International Journal of Molecular Medicine 1(3), pp. 621-625.
Jiang, W. G. and Harding, K. G. 1998. Enhancement of wound tissue expansion and angiogenesis by matrix-embedded fibroblast (dermagraft), a role of hepatocyte growth factor/scatter factor. International Journal of Molecular Medicine 2, pp. 203-210.
Jiang, W. G. 1998. Cell adhesion molecules in the formation of liver metastasis. Journal of Hepato-Biliary-Pancreatic Surgery 5(4), pp. 371-377. (10.1007/s005340050061)

1997

Jiang, W. G. et al. 1997. Regulation of desmosomal cell adhesion in human tumour cells by polyunsaturated fatty acids. Clinical and Experimental Metastasis 15(6), pp. 593-602. (10.1023/A:1018435229087)
Jiang, W. G. and Hiscox, S. E. 1997. beta-catenin-cell adhesion and beyond (review). International Journal of Oncology 11(3), pp. 635-641.
Jiang, W. G., Hiscox, S. E., Horrobin, D. F., Bryce, R. P. and Mansel, R. E. 1997. Gamma linolenic acid regulates expression of maspin and the motility of cancer cells. Biochemical and Biophysical Research Communications 237(3), pp. 639-644. (10.1006/bbrc.1997.7154)
Davies, E., Cochrane, R. A., Hiscox, S. E., Jiang, W. G., Sweetland, H. M. and Mansel, R. E. 1997. The role of desmoglein 2 and E-cadherin in the invasion and motility of human breast cancer cells. International Journal of Oncology 11(2), pp. 415-419.
Hiscox, S. E. and Jiang, W. G. 1997. Regulation of endothelial CD44 expression and endothelium-tumour cell interactions by hepatocyte growth factor/scatter factor. Biochemical and Biophysical Research Communications 233(1), pp. 1-5. (10.1006/bbrc.1997.6388)
Jiang, W. G. and Hiscox, S. E. 1997. Hepatocyte growth factor/scatter factor, a cytokine playing multiple and converse roles. Histology and Histopathology 12(2), pp. 537-555.
Jiang, W. G. and Hiscox, S. 1997. Quantification of tumour cell-endothelial cell attachment by 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine (DiI). Cancer Letters 112(2), pp. 209-217. (10.1016/S0304-3835(96)04573-9)
Hiscox, S. E., Hallett, M. B., Jiang, W. G., Puntis, M. C. A. and Nakamura, T. 1997. Expression of the HGF/SF Receptor, c-met, and its ligand in human colorectal cancers. Cancer Investigation 15(6), pp. 513-521. (10.3109/07357909709047592)
Jiang, W. G. and Puntis, M. C. 1997. Immune dysfunction in patients with obstructive jaundice, mediators and implications for treatments. HPB Surgery 10, pp. 129-142.
Jiang, W. G. and Hiscox, S. 1997. Expression of E-cadherin, alpha, beta and gamma-catenin in human colorectal cancer. Anticancer Research 17, pp. 1349-1354.
Hiscox, S. and Jiang, W. G. 1997. Interleukin-12, an emerging anti-tumour cytokine. In Vivo -Athens- 11, pp. 125-132.
Jiang, W. G. and Bryce, R. P. 1997. Gamma linolenic acid regulates gap junction communication in endothelial cells and their interaction with tumour cells. Prostaglandins Leukotrienes & Essential Fatty Acids 56, pp. 307-316.
Jiang, W. G. and Bryce, R. P. 1997. Regulation of tight junction permeability and occludin expression by polyunsaturated fatty acids. Biochemical and Biophysical Research Communications 244, pp. 414-420.

1996

Jiang, W. G., Hiscox, S., Puntis, M., Bryce, R., Horrobin, D., Mansel, R. E. and Hallett, M. B. 1996. Inhibition of membrane ruffling and ezrin translocation by gamma linolenic acid. International Journal of Oncology 9(2), pp. 279-284. (10.3892/ijo.9.2.279)
Jiang, W. G., Puntis, M. C. A., Horrobin, D. F., Scott, C. and Hallett, M. B. 1996. Inhibition of neutrophil respiratory burst and cytokine priming by γ-linolenic acid. British Journal of Surgery 83(5), pp. 659-664. (10.1002/bjs.1800830523)
Jiang, W. G., Hiscox, S., Puntis, M., Hallett, M. B., Bryce, R., Horrobin, D. and Mansel, R. E. 1996. Gamma linolenic acid inhibits tyrosine phosphorylation of focal adhesion kinase and paxillin and tumour cell matrix interaction. International Journal of Oncology 8(3), pp. 583-587. (10.3892/ijo.8.3.583)
Jiang, W. G. and Hiscox, S. E. 1996. Cytokine regulation of ezrin expression in the human colon cancer cell line HT29.. Anticancer Research 16(2), pp. 861-865.
Jiang, W. G., Hiscox, S., Nakamura, T., Hallett, M. B., Puntis, M. and Mansel, R. E. 1996. Hepatocyte growth factor induces tyrosine phosphorylation of focal adhesion kinase (FAK) and paxillin and enhances cell-matrix interactions. Oncology Reports 3(5), pp. 819-823. (10.3892/or.3.5.819)
Han, Z., Jiang, W. G., Hiscox, S., Hallett, M. B., Isoai, A. and Mansel, R. E. 1996. Inhibition of motility and invasion of human lung cancer cells by invasion inhibiting factor 2. Surgical Oncology 5(2), pp. 77-84. (10.1016/S0960-7404(96)80004-1)
Puntis, M. C. A. and Jiang, W. G. 1996. Plasma cytokine levels and monocyte activation in patients with obstructive jaundice. Journal of Gastroenterology and Hepatology 11, pp. 7-13. (10.1111/j.1440-1746.1996.tb00003.x)
Jiang, W. G. and Puntis, M. C. 1996. Monocyte and blood interleukin-12 levels in patients with obstructive jaundice. Hpb Surgery 9(4), pp. 209-221.
Jiang, W. G. 1996. E-cadherin and its associated protein catenins, cancer invasion and metastasis. British Journal of Surgery 83, pp. 437-446.

1995

Jiang, W. G., Hiscox, S., Hallett, M. B., Horrobin, D., Mansel, R. E. and Puntis, M. 1995. Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). Cancer Research 55, pp. 5043-5048.
Jiang, W. G., Hiscox, S., Hallett, M. B., Horrobin, D. F., Puntis, M. and Mansel, R. E. 1995. Gamma linolenic acid up-regulates e-cadherin expression in human cancer cells. British Journal of Surgery 82(11), pp. 1565-1565.
Jiang, W. G., Hiscox, S., Horrobin, D. F., Hallett, M. B., Mansel, R. E. and Puntis, M. C. 1995. Expression of catenins in human cancer cells and its regulation by n-6 polyunsaturated fatty acids. Anticancer Research 15(6B), pp. 2569-2573.
Jiang, W. G., Hiscox, S., Singhrao, S. K., Nakamura, T., Puntis, M. C. A. and Hallett, M. B. 1995. Inhibition of HGF/SF-induced membrane ruffling and cell motility by transient elevation of cytosolic free Ca2+. Experimental Cell Research 220(2), pp. 424-433. (10.1006/excr.1995.1334)
Jiang, W. G., Hiscox, S., Hallett, M. B., Mansel, R. E. and Puntis, M. C. 1995. Regulation of motility and invasion of cancer cells by human monocytic cells. Anticancer Research 15(4), pp. 1303-1310.
Jiang, W. G., Hiscox, S., Puntis, M. and Hallett, M. B. 1995. Inhibition of HGF/SF-induced tumor-cell membrane ruffling by calcium signalling. British Journal of Surgery 82(5), pp. 682-683.
Jiang, W. G., Hiscox, S., Hallett, M. B., Scott, C., Horrobin, D. and Puntis, M. 1995. Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. British Journal of Cancer 71(4), pp. 744-752. (10.1038/bjc.1995.145)
Hiscox, S., Hallett, M. B., Puntis, M. C. and Jiang, W. G. 1995. Inhibition of cancer cell motility and invasion by interleukin-12. Clinical & Experimental Metastasis 13(5), pp. 396-404. (10.1007/BF00121916)
Jiang, W. G., Hiscox, S., Singhrao, S. K., Puntis, M. C. A., Nakamura, T., Mansel, R. E. and Hallett, M. B. 1995. Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor (HGF/SF). Biochemical and Biophysical Research Communications 217(3), pp. 1062-1069. (10.1006/bbrc.1995.2877)
Jiang, W. G. 1995. Membrane ruffling of cancer cells: a parameter of tumour cell motility and invasion. European Journal of Surgical Oncology (EJSO) 21, pp. 307-309. (10.1016/S0748-7983(95)91690-3)

1994

Jiang, W., Hiscox, S., Hallett, M. B. and Puntis, M. 1994. Induction of motility and invasion by interleukin-3 on human colonic-cancer cells. British Journal of Surgery 81(5), pp. 761-761.
Jiang, W. G. and Puntis, M. D. A. 1994. Effects of gamma linolenic acid and lithium linolinate on human monocytes and hepatoma. In: Horrobin, D. F. ed. New approaches to cancer treatment: Unsaturated lipids and photodynamic therapy. Edinburgh: Churchill-Livingstone, pp. 40-67.
Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Molecular and cellular basis of cancer invasion and metastasis: Implications for treatment. British Journal of Surgery 81(11), pp. 1576-1590. (10.1002/bjs.1800811107)
Jiang, W. G., Puntis, M. C. A. and Hallett, M. B. 1994. Neutrophil priming by cytokines in patients with obstructive jaundice.. HPB Surgery 7(4), pp. 281-289. (10.1155/1994/74202)
Jiang, W. G. 1994. In-vitro models of cancer invasion and metastasis: recent developments. European Journal of Surgical Oncology (EJSO) 20, pp. 493-499.

1993

Jiang, W. G., Lloyds, D., Puntis, M. C. A., Nakamura, T. and Hallett, M. B. 1993. Regulation of spreading and growth of colon cancer cells by hepatocyte growth factor. Clinical & Experimental Metastasis 11(3), pp. 235-242. (10.1007/BF00121166)
Jiang, W. G., Hallett, M. B. and Puntis, M. C. A. 1993. Hepatocyte growth factor/scatter factor, liver regeneration and cancer metastasis. British Journal of Surgery 80(11), pp. 1368-1373. (10.1002/bjs.1800801104)
Jiang, W. G. and Puntis, M. C. 1993. Monocyte secretion of beta-hexosaminidase in patients with obstructive jaundice. HPB Surgery 7, pp. 15-23.

1992

Jiang, W. G., Puntis, M. C., Nakamura, T. and Hallett, M. B. 1992. Neutrophil priming by hepatocyte growth factor, a novel cytokine. Immunology 77(1), pp. 147-149.
Jiang, W. G., Puntis, M. and Hallett, M. B. 1992. U937 cells stimulated with opsonised zymozan particles provide a convenient laboratory source of tumour necrosis factor α. Journal of Immunological Methods 152(2), pp. 201-207. (10.1016/0022-1759(92)90141-F)

Molecular Pathology Module

HGF/cMET in the osteoblastic metastasis of prostate cancer, molecular, cellular and therapeutic implications, in collaboration with Professor Malcolm D Mason
Molecular finger printing of genes linked to cancer progression
Novel molecular wound healing signature, in collaboration with Professor Keith Harding
The molecular, cellular and clinical impacts of SOCS, suppressor of cytokine signalling, in human wound healing, in collaboration with Professor Keith Harding
Anti-metastasis (including peritoneal metastasis) medicines, in collaboration with Peking University and Yiling Research Institute (Professor Jiafu Ji and Professor Yiling Wu)
Brain Metastasis Research Platform, in collaboration with Capital Medical University (Professors Junqi He and Wei Ding)
Evaluation of transglutaminase-4 as a therapeutic target and diagnostic tool in human prostate cancer, in collaboration with Professor Malcolm D Mason and Professor Richard J Ablin (University of Arizona)
Biomarkers in human colorectal cancer research programme, in collaboration with Capital Medical University (Professors Junqi He and Wei Ding)
Cancer Metastasis Platform, in collaboration with Wales Life Science Network

Professor Wen Jiang

Overview

Biography

Honours and awards

Professional memberships

Speaking engagements

Committees and reviewing

Publications

2022

2021

2020

2019

2018

2017

2016

2015

2014

2013

2012