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• subjects: biophysics

1-21 of 21 search results

Name	Qualification	Mode	Type
Medicine The School of Medicine offers research degrees in the medical disciplines such as cancer, immunology, infection, immunity, neurosciences, mental health and population medicine.	PhD, MPhil, MD	Full-time, Part-time	Programme
Structural Biophysics Structural Biophysics is a research area in which you can focus your studies within our PhD programme in Vision Sciences.	PhD	Full-time, Part-time	Area
Vision Sciences Our PhD in Vision Sciences comprises student-led research across a wide range of disciplines, from molecular and cell biology to neuroscience and clinical studies of human vision.	PhD	Full-time, Part-time	Programme
Condensed Matter and Photonics Condensed Matter and Photonics is a research area within which you can focus your studies as part of our suite of Physics and Astronomy research programmes (MPhil, PhD).	PhD, MPhil	Full-time, Part-time	Area
Studying human neuropsychiatric disease in DLG2 deficient human neurons This PhD project in Medicine tries to understand DLG2’s role during neural development and in mature neurons using variety of techniques.			Project
Integration of genetic and functional data to identify drug targets and enhance risk prediction Integrating brain expression and protein-protein interaction data with genomic data identified a network of immune-related genes implicated in Alzheimer’s disease (AD) susceptibility.			Project
Characterising DNA damage repair in Huntington’s disease This is an exciting opportunity to help define the molecular mechanism of Huntington’s disease (HD).			Project
Detecting dysfunction in the single-cell gene networks underlying Parkinson’s disease Parkinson’s disease (PD) is the second most common neurodegenerative disorder and results from the selective loss of dopaminergic neurons within the Substantia nigra pars compacta.			Project
Microglial NFAT signalling and Alzheimer’s disease genetic risk networks In this project, you will develop skills in molecular biological, cell culture, genome biology and bioinformatics.			Project
The molecular basis of cognitive flexibility This project examines transcriptomes in key brain regions at critical periods to determine the molecular bases of flexible behaviour.			Project
Investigating peroxisome dysregulation in Alzheimer’s disease In this project you will first determine how peroxisomes respond to the specific pathogenic proteins associated with AD in vivo.			Project
Targeting LAG3+ T cells for Cancer Immunotherapy This study will look at the control of adaptive immunity in health and inflammation by human blood and mucosal gamma/delta T cells.			Project
Machine Learning for Prediction in Alzheimer's Disease: Identifying Novel Biologically Valid Diagnostic Categories to Inform Precision Medicine The project will involve investigating the ability of machine learning.			Project
Alzheimer’s disease: Understanding the interaction of microglia risk genes The aim of this project is to understand the interdependence of specific risk alleles and highlight the possibility of adjunctive therapies targeting different ‘arms’ of the immune cells to treat the disease.			Project
Investigating the childhood neurodevelopmental origins of adult mental illness This PhD utilises new data generated by a Wellcome Trust Collaborative Award between Cardiff and Bristol Universities to test hypotheses on why child NDDs show links with later adult mental illness.			Project
Flexible vectors for immunotherapy against cancer and pathogens This project aims to determine pathways that can drive the growth of particular types of NK and T cells that are optimised to provide better protection from disease. We will use cytomegalovirus and leukaemic cells as systems of analysis.			Project
Enhancing immune stimulation for novel anti-cancer viral vaccine vectors We will combine cutting-edge proteomics with molecular virology and immunology to determine how HCMV induces such strong responses, enabling us to generate optimised vaccine vectors.			Project
Role of a mouse ortholog of CR1 (crry) in the 3xTG model of Alzheimer’s Disease (AD) In order to explore further roles of Crry, we have generated and established a 3xTG/Crry-/- colony, but have not yet had resources to explore further the impact of Crry deficiency in this model.			Project
Optimizing adult mental health outcomes in children with neurodevelopmental problems: interplay of social and genetic factors This PhD project provides a unique opportunity to develop advanced methodological and analytic skills in the field of developmental psychopathology.			Project
School experiences in children at high genetic risk of mental health problems This project will provide important insights into why children with a genomic disorder struggle in school.			Project
Molecular mechanisms of CRISPR Cas9 nickase-induced CAG/CTG repeat contraction: Implications for gene editing in expanded repeat disorders The aim of this project is to understand how contractions occur at the molecular level such that we can make a potential gene editing-based treatment safer and more efficient.			Project