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Name Qualification Mode Type

Molecular Biosciences

Molecular Biosciences focuses on the molecular mechanisms underpinning biological function.

PhD, MPhil, MD Full-time, Part-time Area

Biosciences

Our research ranges across the biological sciences, from the understanding of precisely how neurons grow, to the mechanisms of cancer and other diseases, the molecular basis of animal and plant development and exploring the genetics of orang-utans, elephants, pandas and other endangered species.

PhD, MPhil, MD Full-time, Part-time Programme

Structural analysis of receptors for insecticidal toxins

Insecticidal toxins produced by bacteria such as Bacillus thuringiensis and Lysinibacillus sphaericus are the active agents in these important biological pesticides and can also be exploited in the production of insect-resistant transgenic plants.

Project

Cytoplasmic RNA regulation in cell motility

This project will investigate how cytoplasmic RNA regulation impacts on cell motility and immune function, by studying conserved RNA-binding proteins and their interactions with candidate mRNAs.

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Protein interactions in the regulation of a model cell differentiation program

Cell differentiation programs drive the production of specialised tissues from progenitor cells during animal development.

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Role of the lysosome, and the lysosomal protein NPC1 in the pathogenesis and treatment of Mycobacteriumtuberculosis

Tuberculosis (TB) is a chronic disease that in it’s latent form affects approximately one third of the worlds population with an estimated 10 million new cases and 1.5 million deaths per year.

Project

Firing dynamics of thalamic and cortical neural networks during absence epilepsy

Epilepsy is one of the most serious and widespread neurological diseases, which affect about 1% of the population.

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A Synthetic Reaction-Diffusion System for Engineering Patterning and Self-Organisation in Plant Stem Cells

Reaction-diffusion systems are employed in biology to establish patterns associated with the formation of distinct tissues and organs at the multicellular scale.

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Molecular pathways regulating stem cell divisions

This project aims to identify the molecular pathways that regulate proliferative vs. neurogenic divisions in the developing cerebral cortex by combining candidate and unbiased approaches.

Project

Characterisation of microRNAs regulated by dihomo-gamma-linolenic acid in macrophages in relation to atherosclerosis

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for more deaths in the western world than any other disease with mortality increasing at a marked rate in developing countries.

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Examining the programming of offspring behaviour by maternal diet and abnormal maternal care

There is a well-defined association between early life adversity (either prenatally or in early childhood) and significantly poorer outcomes for children.

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Towards the clinical development of calcium-sensing receptor antagonists as novel therapeutics for inflammatory lung diseases

G protein-coupled receptors (GPCRs) have crucial roles in almost every physiological process from cardiac function, immune responses and neurotransmission to sensory functions comprising sight, taste and smell.

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The smell of infection – detecting infectious disease and determining mechanisms underlying the spread of disease on social networks

Social organization facilitates contacts between individuals altering the probability of parasite transmission (Perkins et al., 2009).

Project

Can early intervention with astrocytes delay the progression of Huntington's disease?

We will test the hypothesis that astrocyte transplants can improve function in an adult HD mouse model, thereby taking the first steps towards exploring astrocyte transplants as a potential therapy for HD.

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Invertebrate communities in hollowing trees

This project aims to define how heart-rot decay characteristics, succession and landscape context govern the composition and structure of fungal-invertebrate assemblages.

Project

Competitive ability of a highly invasive plant: The interplay between resource availability, herbivory and allelopathy

This project aims to investigate the role of resource competition and allelopathy, under different environmental conditions, particularly in the context of varying resource availability and herbivory, in facilitating the invasion of Himalayan balsam (Impatiens glandulifera).

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