Skip to main content
Dr Emma Tallantyre

Dr Emma Tallantyre

Clinical Senior Lecturer, Division of Psychological Medicine and Clinical Neurosciences

School of Medicine

Email
tallantyreec@cardiff.ac.uk
Telephone
+44 (0)29 2074 5403
Campuses
Room 91E, 4th Floor B-C Link Corridor, University Hospital Wales
Users
Available for postgraduate supervision

Overview

I graduated from medical school at the University of Nottingham in 2002. I undertook my postgraduate medical and neurological training in Nottingham, Derby, Australia and South Wales. As an MRC research fellow, I completed a PhD investigating imaging (Sir Peter Mansfield MR centre) and neuropathology (Nottingham University) of multiple sclerosis (MS).

I have been involved in the clinical care of people with MS since 2006. I completed my clinical training in 2015 and became a Clinical Senior Lecturer in Neurology in 2018. I hold an honorary contract to work within the Helen Durham Neuroinflammatory Unit of the University Hospital of Wales. As part of this role I run weekly MS and general neurology clinics and contribute to service development.

My current research interests centre on the outcomes of neuroinflammatory disease. I am involved in clinical trials that investigate the optimum treatment approaches in multiple sclerosis. I have an interest in combining real world clinical data with associated biological and imaging data to strengthen predictions of outcome and improve trial design. I am also interested in the involvement of patients and the public in the development of clinical research studies.

Biography

Academic and clinical positions

Clinical Senior Lecturer

Cardiff University

March 2018 - present

Consultant Neurologist

University Hospital of Wales

March 2017 – Feb 2018

Clinical Senior Lecturer

Cardiff University

March 2016 – Feb 2017

Post-CCT Research Fellow

Neurology SpR

University Hospital of Wales

Wales Deanery

July 2015 –Feb 2016

Aug 2012 – July 2015

Neurology SpR

East Midlands Deanery

August 2009 – August 2012

Professional memberships

  • Member of Royal College of Physicians
  • Association of British Neurology
  • General Medical Council licence to practice

Speaking engagements

  • Facebook Live public engagement on Progressive MS, (Virtual Meeting), Nov 2020
  • Virtual Management of MS. Raising the Bar (Virtual Meeting), Nov 2020.
  • Biogen webinar on Real World Data, (Virtual Meeting). October 2020
  • Multiple Sclerosis: current landscape, ongoing challenges and unmet needs. CITER, Cardiff University, (Virtual Meeting). September 2020.
  • Symposium at Association of British Neurology on Secondary Progressive MS, (Virtual Meeting). September 2020.
  • Secondary Immune Deficiency in Neurology. Takeda Global Immunology Forum, Berlin. January 2020.
  • An Update on DMTs in MS. Royal College of Physicians A-Z of MS. London, November 2019.
  • Personalised Medicine in MS. MS Frontiers, Bath, July 2019.
  • What is the next drug for MS? Invited talk at Association of British Neurologists Annual Meeting, Birmingham, May 2018.
  • Multiple Sclerosis Academy, MS Masterclass, Sheffield, 2017
  • MS Society Cymru 60th anniversary event, Cardiff, 2017.
  • How common is truly benign MS? EC Tallantyre, P Major, WA Davies, M Atherton, K Harding, T Pickersgill, M Winter, N Robertson. Association of British Neurologists Annual Meeting, Liverpool, May 2017.
  • Secondary Antibody Deficiency and infection following B-cell depletion for CNS neuroinflammation. EC Tallantyre, D Whittam, S Jolles, N Robertson, A Jacob. Association of British Neurologists Annual Meeting, Liverpool, May 2017.
  • Biogen MRI in MS meeting, co-organiser and speaker, Cardiff, 2017
  • National MS Debating society, Edinburgh, 2017.
  • Grand Challenge workshop: designing a next generation clinical trial in MS, London, 2016.
  • Becoming a neurology trainee: Mentoring, top tips for research & audit work-life balance. Foundation Doctors Session, Association of British Neurologists Annual Meeting, Harrogate, May 2015.
  • MS Trust annual conference, Windsor, 2015.
  • The Shape of Training. Association of British Neurologists Annual Meeting, Cardiff, May 2014.
  • Differential diagnosis in a Relapse Clinic. South Wales MS Day, May 2013.

    Committees and reviewing

    I regularly review manuscripts for peer-reviewed publication.

    I am a reviewer and have interviewed for grant awards via the Association of British Neurology.

    I have also reviewed grant awards to MRC and MS Society.

    Publications

    2021

    2020

    2019

    2018

    2017

    2016

    2015

    2013

    Teaching

    I contribute to the C21 Medical Undergraduate neurology teaching. I am clinical tutor to 4th year students rotating through Neurology placements and have also been undergraduate tutor to a group of 1st – 2nd year students since they entered the medical course.

    I run a regular programme of 3rd and 4th year SSC projects as well as BSc intercalated projects for the undergraduate medical course. We receive consistently good feedback from our students and enjoy the interaction they bring to the department.

    I organise teaching and training days for Neurology Specialty trainees across the region on subjects including Neuropathology, Neuroimaging and Neuro-oncology, with guest speakers and a range of formats.

    I am examiner in undergraduate formative and summative pratical examinations (OSCE/ ISCE).

    I have experience in using high field structural imaging to visualise white matter and grey matter pathology in the brains of people with MS. During my PhD I correlated in vivo MR imaging findings with the neurodegenerative pathology seen in the post mortem brains and spinal cords of those with longstanding MS.

    My current research interests centre on the outcomes of neuroinflammatory disease. I am involved in clinical trials that investigate the optimum treatment approaches in multiple sclerosis. I contribute to a long running epidemiological project, prospectively collecting clinical data from a population-based cohort of people with neuroinflammatory diseases including MS. I have an interest in combining this real world clinical data with associated biological and imaging data to strengthen predictions of outcome and improve trial design. I am also interested in the involvement of patients and the public in the development of clinical research studies.

    Grants and Awards

    • MRC Confidence in Concept award. (Lead applicant). Diagnostic and predictive biomarkers in Multiple Sclerosis plasma: a comprehensive screening approach. £48,671 (100% to Cardiff). Dec 2019 – June 2021. 1h per week.
    • Wellcome Institutional Strategic Support Funding Population award. (Lead applicant). Contemporary modelling of Multiple Sclerosis outcomes in a South Wales population. (Principal Applicant). £47,760 (100% received). Sept 2019 – Dec 2021. 0.5h per week.
    • National Multiple Sclerosis Society (US) and Uk MS Society; Joint Application for additional funds. Biobanking in Treatment Approach Studies in Relapsing Remitting Multiple Sclerosis. (Lead Applicant at sub-contracted site). £29,134 (100% to Cardiff). April 2019 – Dec 2022. 0.5h per week.
    • National Institute for Health Research. DECISIve - DiagnosE using the Central veIn SIgn. A prospective diagnostic superiority study comparing T2* MRI and lumbar puncture in patients presenting with possible Multiple Sclerosis. (Co-applicant). £349,461 [£27,250 to Cardiff]. July 2019 – June 2022. 0.5h per week.
    • Dowager Eleanor Peel Trust (Principal applicant) Serum Neurofilaments in multiple sclerosis. £9,936 (100% received). September 2018 – September 2019.
    • Patient-Centred Outcome Research Institute (PCORI; co-applicant) 2017 - Determining the Effectiveness of Early Intensive versus Escalation Approaches for the Treatment of Relapsing-Remitting Multiple Sclerosis (DELIVER-MS) -£7.5m.
    • MS Society 2017 (co-applicant) - Life-style, Exercise and Activity Package for People living with Progressive Multiple Sclerosis (LEAP-MS) - £293,000.
    • Health and Care Research Wales - Clinical Research Award 2016 - £67,927
    • Wellcome Trust Institutional Strategic Support Fund Award (co-applicant) 2015 - £34,000
    • Trainees Transforming Training 2015 - £5,000
    • Biogen Idec MS Global Registry Fellowship 2014 - £62,000
    • MRC Clinical Training Fellowship, 2007 - £100,000
    • Peele Medical Trust, Research grant, 2006 - £5,000

    Supervision

    I am interested in supervising PhD students in

    Neuroinflammatory disease

    Neuroimaging in MS

    Past projects

    Co-supervisor (50%) to Ray Wynford-Thomas (2018- )

    Educational supervisor to postgraduate trainees in Medicine and Neurology.

    Engagement

    I am involved in public engagament via various channels. We engage with our cohort of people with neuroinflamamtory disease via regular newsletters and patient information days. We have run numerous patient and stakeholder focus groups to guide and influence our research. I was involved in patient consultation during the development of the DELIVER-MS trial, including developing video media to aid consent. We published on metholodolgy, which was considered an exemplar for contemporary clinical trial engagement. I have provided public-facing information (Q&A) sessions on Facebook and Zoom Webinar. I am part of the Inspiring the Future scheme that seeks to promote STEM subjects for children.