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Dr Sophie Legge

Dr Sophie Legge

Research Associate, Division of Psychological Medicine and Clinical Neurosciences

Email
leggese8@cardiff.ac.uk
Telephone
+44 (0)29 2068 8837
Campuses
2.30, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ

Overview

My research is primarily focused on the contribution of genetic and environmental factors to the development of psychosis and schizophrenia.

I am interested in dissecting the heterogeneity and dimensionality of schizophrenia by identifying biologically valid phenotypic constructs.

I am also interested in pharmacogenetics, specifically in relation to clozapine use and the Duffy-null genetic variant. My PhD (completed in 2016) was focused on identifying predictors of treatment-resistant schizophrenia, and the genetic causes of clozapine-induced neutropenia, a rare adverse effect of the antipsychotic clozapine.

Biography

Publications

2022

2021

2020

2019

2018

2017

2016

2015

2014

2013

2012