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Dr Ashish Radadiya

Dr Ashish Radadiya

Postdoctoral Research Associate (with Prof Nigel Richards)

School of Chemistry


As a multi-disciplinary researcher, I combine in-silico calculations with experiments to solve problems in medicinal chemistry and chemical biology. My unique training gives me the ability to identify and prepare novel small molecules that can be used to treat advanced complex diseases and to overcome drug resistance.

In-silico expertise includes QM calculations, protein modelling, homology modelling, molecular docking, virtual screening, pharmacophore modelling, structure activity relationship, QSAR, molecular dynamics (MD) simulations and free energy estimates.

Experimental expertise includes organic synthesis and purification of biologically active small molecules, and their characterisation using various spectroscopic and chromatographic tools-techniques.


  • 2017 - present: Postdoctoral Research Associate, Cardiff University, School of Chemistry
  • 2010 - 2017: In-charge, molecular modelling facility, National Facility for Drug Discovery Centre (CoE-NFDD), Rajkot, India
  • 2010 - 2016: PhD (Chemistry), Saurashtra University, Rajkot, India (Prof. Anamik Shah)
  • 2009: Industrial dissertation project training, R & D Centre - Torrent Pharmaceutical Limited, India (Dr. Appaji Mandhare)
  • 2007 - 2009: M.Sc. Bioinformatics, Sardar Patel University, India
  • 2004 - 2007: B.Sc. Chemistry, Sardar Patel University, India

Honours and awards

  • 2015-2016: Meritorious Senior Research Fellow (SRF), Fellow University Grants Commission, New Delhi, India (UGC-BSR-SRF)
  • 2012: International travel grant for attending "Quantum Monte Carlo and the CASINO program VI", Cambridge International Summer School, Tuscany, Italy – funded by Council of Scientific and Industrial Research (CSIR), Govt of India.

  • 2011-2014: Meritorious Junior Research Fellow, Fellow University Grants Commission, New Delhi, India (UGC-BSR-JRF)
  • 2011: Best poster prize awarded at 15th ISCB International Conference organized by India Society of Chemists and Biologists.











Current projects include:

  • Computational modelling of asparagine synthetase bound to inhibitors using classical all atom MD simulations, and the synthesis of novel asparagine synthetase inhibitors with use in treating sarcoma.
  • Homology modelling of human NAD+ synthetase.
  • QM and free energy perturbation calculations in studies of non-natural nucleobases.
  • Synthesis and characterisation of CK2-alpha inhibitors.