Skip to content
Professor William Gray

Professor William Gray

Professor of Functional Neurosurgery, Neuroscience & Mental Health Research Institute

School of Medicine

Email:
graywp@cardiff.ac.uk
Telephone:
+44 (0)29 2068 8491
Location:
3.33, Main Hospital Building, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN

I am the director of Health and Care Research Wales funded BRAIN Unit and Professor of Neurosurgery. I undertake clinical research in epilepsy, the hippocampus, learning and memory.

My research involves imaging of epilepsy patients to understand seizure origins and cognitive dysfunction, intracranial EEG recordings, imaging white matter fibre streams, imaging grey matter structure, microstructure and fMRI.

2019

2018

2017

2016

2015

2014

2013

2012

2011

2010

2009

2008

2007

2006

2005

2003

2002

1999

1998

1997

1996

1990

Human Brain Tissue & CSF for Translational Research

Tissue obtained from Brain Surgery- Excess tissue removed is used for research

  • Epilepsy Surgery
  • Tumour Surgery
  • Head injury surgery

Culturing Human Brain tissue in 3D

  • Ex vivo human tissue
  • 3D culture
  • Heterogeneity
  • High Density
  • Air-liquid interface
  • Semi-permeable membrane insert

We use cultures of human brain to study how the brain works and what goes wrong in disease

Collaboration with Dr F Siebzehnrubl, Dr M Zaben & Prof W Gray

We are using brain tissue to assess the effectiveness of cell transplantation for brain repair

Collaboration with Dr Y Zhu, Dr A Errington, Prof Meng Li &  Prof W Gray.

Early Diagnoses of Brain Infection

Using Cerebrospinal Fluid (CSF) samples from patients with suspected infection we are examining the use of immune markers to accurately diagnose infection much earlier than with standard micriobiology cultures and so treat patients earlier.

Collab with Prof M Ebryl, Dr S Cuff, Dr J Merola & Prof W Gray.

(Refer to Images 1, 2 and 3 in right hand menu)*