Publications
2024
2023
- Naha, S. et al. 2023. Carriage and within-host diversity of mcr-1.1-harboring Escherichia coli from pregnant mothers: inter- and intra-mother transmission dynamics of mcr-1.1. Emerging Microbes & Infections 12, article number: 2278899. (10.1080/22221751.2023.2278899)
- Bhattacharjee, A. et al. 2023. A decade-long evaluation of neonatal septicaemic escherichia coli: Clonal lineages, genomes, and New Delhi metallo-beta-lactamase variants. Microbiology Spectrum 11(4) (10.1128/spectrum.05215-22)
- David, S. et al. 2023. Genomic surveillance of multidrug-resistant Klebsiella in Wales reveals persistent spread of Klebsiella pneumoniae ST307 and adaptive evolution of pOXA-48-like plasmids. Microbial Genomics 9(5) (10.1099/mgen.0.001016)
- Umair, M. et al. 2023. International manufacturing and trade in colistin, its implications in colistin resistance and One Health global policies: a microbiological, economic, and anthropological study. The Lancet Microbe 4(4), pp. E264-E276. (10.1016/S2666-5247(22)00387-1)
- Khan, U. B., Portal, E. A. R., Sands, K., Lo, S., Chalker, V. J., Jauneikaite, E. and Spiller, O. B. 2023. Genomic analysis reveals new integrative conjugal elements and transposons in GBS conferring antimicrobial resistance. Antibiotics 12(3), article number: 544. (10.3390/antibiotics12030544)
- Farzana, R. et al. 2023. Genomic insights into the mechanism of carbapenem resistance dissemination in Enterobacterales from a tertiary public heath setting in South Asia. Clinical Infectious Diseases 76(1), pp. 119-133. (10.1093/cid/ciac287)
2022
- Carvalho, M. J. et al. 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7, pp. 1337-1347. (10.1038/s41564-022-01184-y)
- Martins, W. M. et al. 2022. Diversity of lytic bacteriophages against XDR Klebsiella pneumoniae sequence type 16 recovered from sewage samples in different parts of the world. Science of the Total Environment 839, article number: 156074. (10.1016/j.scitotenv.2022.156074)
- Sands, K. et al. 2022. Characterisation of Staphylococci species from neonatal blood cultures in low- and middle-income countries. BMC Infectious Diseases 22(1), article number: 593. (10.1186/s12879-022-07541-w)
- Martins, W. M. et al. 2022. Silent circulation of BKC-1-producing Klebsiella pneumoniae ST442: molecular and clinical characterization of an early and unreported outbreak. International Journal of Antimicrobial Agents 59(5), article number: 106568. (10.1016/j.ijantimicag.2022.106568)
- Milton, R. et al. 2022. Neonatal sepsis and mortality in low-income and middle-income countries from a facility-based birth cohort: an international multisite prospective observational study. The Lancet Global Health 10(5), pp. e661-e672. (10.1016/S2214-109X(22)00043-2)
- Acolatse, J. E. E. et al. 2022. Environmental surveillance of ESBL and carbapenemase-producing gram-negative bacteria in a Ghanaian Tertiary Hospital. Antimicrobial Resistance and Infection Control 11(1), article number: 49. (10.1186/s13756-022-01090-2)
- Sands, K., Spiller, O. B., Thomson, K., Portal, E. A. R., Iregbu, K. C. and Walsh, T. R. 2022. Early-onset neonatal sepsis in low- and middle-income countries: current challenges and future opportunities. Infection and Drug Resistance 2022, pp. 933—946. (10.2147/IDR.S294156)
- Boostrom, I., Portal, E. A. R., Spiller, O. B., Walsh, T. R. and Sands, K. 2022. Comparing long-read assemblers to explore the potential of a sustainable low-cost, low-infrastructure approach to sequence antimicrobial resistant bacteria with Oxford nanopore sequencing. Frontiers in Microbiology 13, article number: 796465. (10.3389/fmicb.2022.796465)
- Martins, W. M. B. S. et al. 2022. Effective phage cocktail to combat the rising incidence of extensively drug-resistant Klebsiella pneumoniae sequence type 16. Emerging Microbes and Infections 11(1), pp. 1015 -1023. (10.1080/22221751.2022.2051752)
2021
- Boostrom, I. et al. 2021. Evaluation of the MYCOPLASMA IST3 urogenital mycoplasma assay in an international multicentre trial. Journal of Antimicrobial Chemotherapy 76(12), pp. 3175-3182. (10.1093/jac/dkab320)
- Thomson, K. M. et al. 2021. Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS). The Lancet Infectious Diseases 21(12), pp. 1677-1688. (10.1016/S1473-3099(21)00050-5)
- Sharratt, M. et al. 2021. Defining fluoroquinolone resistance-mediating mutations from non-resistance polymorphisms in Mycoplasma hominis Topoisomerases. Antibiotics 10(11), article number: 1379. (10.3390/antibiotics10111379)
- Spiller-Boulter, O., Paukner, S., Boostrom, I., Sands, K., Portal, E. A. R. and Spiller, O. B. 2021. Determination of in vitro antimicrobial susceptibility for Lefamulin (Pleuromutilin) for Ureaplasma Spp. and Mycoplasma hominis. Antibiotics 10(11), article number: 1370. (10.3390/antibiotics10111370)
- Hassan, B. et al. 2021. A role for arthropods as vectors of multidrug-resistant Enterobacterales in surgical site infections from South Asia. Nature Microbiology 6(10), pp. 1270. (10.1038/s41564-021-00965-1)
- Portal, E., Sands, K., Portnojs, A., Chalker, V. . J. and Spiller, O. B. 2021. Legionella antimicrobial sensitivity testing: comparison of microbroth dilution with BCYE and LASARUS solid media. Journal of Antimicrobial Chemotherapy 76(5), pp. 1197-1204. (10.1093/jac/dkaa535)
- Sands, K. et al. 2021. Characterization of antimicrobial resistant Gram-negative bacteria that cause neonatal sepsis in seven low and middle-income countries. Nature Microbiology 6, pp. 512–523. (10.1038/s41564-021-00870-7)
- Mentasti, M., David, S., Sands, K., Khan, S., Davies, L., Turner, L. and Wootton, M. 2021. Rapid detection and differentiation of mobile colistin resistance (mcr-1 to mcr-10) genes by real-time PCR and melt-curve analysis. Journal of Hospital Infection 110, pp. 148-155. (10.1016/j.jhin.2021.01.010)
- Roch, M. et al. 2021. Vertical and horizontal dissemination of an IncC plasmid harbouring rmtB 16S rRNA methylase gene, conferring resistance to plazomicin, among invasive ST258 and ST16 KPC-producing Klebsiella pneumoniae. Journal of Global Antimicrobial Resistance 24, pp. 183-189. (10.1016/j.jgar.2020.12.006)
- Tansawai, U. et al. 2021. Emergence of mcr-3-mediated IncP and IncFII plasmids in Thailand. Journal of Global Antimicrobial Resistance 24, pp. 446-447. (10.1016/j.jgar.2021.02.006)
- Chalker, V. J. et al. 2021. Tetracycline resistance mediated by tet(M) has variable integrative conjugative element composition in Mycoplasma hominis isolated in the United Kingdom from 2005-2015.. Antimicrobial Agents and Chemotherapy 65, article number: e02513-20. (10.1128/AAC.02513-20)
- Naha, S., Sands, K., Mukherjee, S., Saha, B., Dutta, S., Basu, S. and Bradford, P. A. 2021. OXA-181-like carbapenemases in Klebsiella pneumoniae ST14, ST15, ST23, ST48, and ST231 from septicemic neonates: coexistence with NDM-5, resistome, transmissibility, and genome diversity. mSphere 6(1), article number: e01156-20. (10.1128/mSphere.01156-20)
2020
- Morris, D. J., Jones, L. C., Davies, R. L., Sands, K., Portal, E. and Spiller, O. B. 2020. MYCO WELL D-ONE detection of Ureaplasma spp. and Mycoplasma hominis in sexual health patients in Wales. European Journal of Clinical Microbiology and Infectious Diseases 39, pp. 2427-2440. (10.1007/s10096-020-03993-7)
- Martins, W. M. B. S. et al. 2020. Clinical and molecular description of a high-copy IncQ1 KPC-2 plasmid harbored by the international ST15 Klebsiella pneumoniae clone. mSphere 5, article number: e00756-20. (10.1128/mSphere.00756-20)
- Andrey, D. O. et al. 2020. An emerging clone, KPC-2-producing Klebsiella pneumoniae ST16, associated with high mortality rates in a CC258 endemic setting. Clinical Infectious Diseases 71(7), pp. e141-e150. (10.1093/cid/ciz1095)
- Farzana, R. et al. 2020. Molecular and epidemiological analysis of a Burkholderia cepacia sepsis outbreak from a tertiary care hospital in Bangladesh. PLoS Neglected Tropical Diseases 14(4), article number: e0008200. (10.1371/journal.pntd.0008200)
- Naha, S. et al. 2020. KPC-2-producing Klebsiella pneumoniae ST147 in a neonatal unit: Clonal isolates with differences in colistin susceptibility attributed to AcrAB-TolC pump. International Journal of Antimicrobial Agents 55(3), article number: 105903. (10.1016/j.ijantimicag.2020.105903)
- Yee Lim, S. et al. 2020. Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International Journal of Pharmaceutics 573, article number: 118860. (10.1016/j.ijpharm.2019.118860)
2019
- Mentasti, M., Prime, K., Sands, K., Khan, S. and Wootton, M. 2019. Rapid detection of IMP, NDM, VIM, KPC and OXA-48-like carbapenemases from enterobacteriales and gram-negative non-fermenter bacteria by real-time PCR and melt-curve analysis. European Journal of Clinical Microbiology and Infectious Diseases 38(11), pp. 2029-2036. (10.1007/s10096-019-03637-5)
- Farzana, R. et al. 2019. Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh. Journal of Infection in Developing Countries 13(8), pp. 773-776. (10.3855/jidc.11541)
- Farzana, R. et al. 2019. Outbreak of hypervirulent multi-drug resistant Klebsiella variicola causing high mortality in neonates in Bangladesh. Clinical Infectious Diseases 7, pp. 1225-1227. (10.1093/cid/ciy778)
- Yang, Q. E. et al. 2019. Environmental dissemination of mcr-1 positive Enterobacteriaceae by Chrysomya spp. (common blowfly): An increasing public health risk. Environment International 122, pp. 281-290. (10.1016/j.envint.2018.11.021)
2017
2016
2014
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O., Marsh, L. L. and Wise, M. P. 2014. Mechanisms of augmented growth of Pseudomonas aeruginosa mediated by Candida albicans [Letter]. Critical Care Medicine 42(3), pp. e256. (10.1097/CCM.0000000000000113)
2013
Articles
- Nieto-Rosado, M. et al. 2024. Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria. Nature Communications 15, article number: 2758. (10.1038/s41467-024-46684-z)
- Portal, E. A. R. et al. 2024. Characterisation of colistin resistance in Gram-negative microbiota of pregnant women and neonates in Nigeria. Nature Communications 15(1), article number: 2302. (10.1038/s41467-024-45673-6)
- Naha, S. et al. 2023. Carriage and within-host diversity of mcr-1.1-harboring Escherichia coli from pregnant mothers: inter- and intra-mother transmission dynamics of mcr-1.1. Emerging Microbes & Infections 12, article number: 2278899. (10.1080/22221751.2023.2278899)
- Bhattacharjee, A. et al. 2023. A decade-long evaluation of neonatal septicaemic escherichia coli: Clonal lineages, genomes, and New Delhi metallo-beta-lactamase variants. Microbiology Spectrum 11(4) (10.1128/spectrum.05215-22)
- David, S. et al. 2023. Genomic surveillance of multidrug-resistant Klebsiella in Wales reveals persistent spread of Klebsiella pneumoniae ST307 and adaptive evolution of pOXA-48-like plasmids. Microbial Genomics 9(5) (10.1099/mgen.0.001016)
- Umair, M. et al. 2023. International manufacturing and trade in colistin, its implications in colistin resistance and One Health global policies: a microbiological, economic, and anthropological study. The Lancet Microbe 4(4), pp. E264-E276. (10.1016/S2666-5247(22)00387-1)
- Khan, U. B., Portal, E. A. R., Sands, K., Lo, S., Chalker, V. J., Jauneikaite, E. and Spiller, O. B. 2023. Genomic analysis reveals new integrative conjugal elements and transposons in GBS conferring antimicrobial resistance. Antibiotics 12(3), article number: 544. (10.3390/antibiotics12030544)
- Farzana, R. et al. 2023. Genomic insights into the mechanism of carbapenem resistance dissemination in Enterobacterales from a tertiary public heath setting in South Asia. Clinical Infectious Diseases 76(1), pp. 119-133. (10.1093/cid/ciac287)
- Carvalho, M. J. et al. 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7, pp. 1337-1347. (10.1038/s41564-022-01184-y)
- Martins, W. M. et al. 2022. Diversity of lytic bacteriophages against XDR Klebsiella pneumoniae sequence type 16 recovered from sewage samples in different parts of the world. Science of the Total Environment 839, article number: 156074. (10.1016/j.scitotenv.2022.156074)
- Sands, K. et al. 2022. Characterisation of Staphylococci species from neonatal blood cultures in low- and middle-income countries. BMC Infectious Diseases 22(1), article number: 593. (10.1186/s12879-022-07541-w)
- Martins, W. M. et al. 2022. Silent circulation of BKC-1-producing Klebsiella pneumoniae ST442: molecular and clinical characterization of an early and unreported outbreak. International Journal of Antimicrobial Agents 59(5), article number: 106568. (10.1016/j.ijantimicag.2022.106568)
- Milton, R. et al. 2022. Neonatal sepsis and mortality in low-income and middle-income countries from a facility-based birth cohort: an international multisite prospective observational study. The Lancet Global Health 10(5), pp. e661-e672. (10.1016/S2214-109X(22)00043-2)
- Acolatse, J. E. E. et al. 2022. Environmental surveillance of ESBL and carbapenemase-producing gram-negative bacteria in a Ghanaian Tertiary Hospital. Antimicrobial Resistance and Infection Control 11(1), article number: 49. (10.1186/s13756-022-01090-2)
- Sands, K., Spiller, O. B., Thomson, K., Portal, E. A. R., Iregbu, K. C. and Walsh, T. R. 2022. Early-onset neonatal sepsis in low- and middle-income countries: current challenges and future opportunities. Infection and Drug Resistance 2022, pp. 933—946. (10.2147/IDR.S294156)
- Boostrom, I., Portal, E. A. R., Spiller, O. B., Walsh, T. R. and Sands, K. 2022. Comparing long-read assemblers to explore the potential of a sustainable low-cost, low-infrastructure approach to sequence antimicrobial resistant bacteria with Oxford nanopore sequencing. Frontiers in Microbiology 13, article number: 796465. (10.3389/fmicb.2022.796465)
- Martins, W. M. B. S. et al. 2022. Effective phage cocktail to combat the rising incidence of extensively drug-resistant Klebsiella pneumoniae sequence type 16. Emerging Microbes and Infections 11(1), pp. 1015 -1023. (10.1080/22221751.2022.2051752)
- Boostrom, I. et al. 2021. Evaluation of the MYCOPLASMA IST3 urogenital mycoplasma assay in an international multicentre trial. Journal of Antimicrobial Chemotherapy 76(12), pp. 3175-3182. (10.1093/jac/dkab320)
- Thomson, K. M. et al. 2021. Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS). The Lancet Infectious Diseases 21(12), pp. 1677-1688. (10.1016/S1473-3099(21)00050-5)
- Sharratt, M. et al. 2021. Defining fluoroquinolone resistance-mediating mutations from non-resistance polymorphisms in Mycoplasma hominis Topoisomerases. Antibiotics 10(11), article number: 1379. (10.3390/antibiotics10111379)
- Spiller-Boulter, O., Paukner, S., Boostrom, I., Sands, K., Portal, E. A. R. and Spiller, O. B. 2021. Determination of in vitro antimicrobial susceptibility for Lefamulin (Pleuromutilin) for Ureaplasma Spp. and Mycoplasma hominis. Antibiotics 10(11), article number: 1370. (10.3390/antibiotics10111370)
- Hassan, B. et al. 2021. A role for arthropods as vectors of multidrug-resistant Enterobacterales in surgical site infections from South Asia. Nature Microbiology 6(10), pp. 1270. (10.1038/s41564-021-00965-1)
- Portal, E., Sands, K., Portnojs, A., Chalker, V. . J. and Spiller, O. B. 2021. Legionella antimicrobial sensitivity testing: comparison of microbroth dilution with BCYE and LASARUS solid media. Journal of Antimicrobial Chemotherapy 76(5), pp. 1197-1204. (10.1093/jac/dkaa535)
- Sands, K. et al. 2021. Characterization of antimicrobial resistant Gram-negative bacteria that cause neonatal sepsis in seven low and middle-income countries. Nature Microbiology 6, pp. 512–523. (10.1038/s41564-021-00870-7)
- Mentasti, M., David, S., Sands, K., Khan, S., Davies, L., Turner, L. and Wootton, M. 2021. Rapid detection and differentiation of mobile colistin resistance (mcr-1 to mcr-10) genes by real-time PCR and melt-curve analysis. Journal of Hospital Infection 110, pp. 148-155. (10.1016/j.jhin.2021.01.010)
- Roch, M. et al. 2021. Vertical and horizontal dissemination of an IncC plasmid harbouring rmtB 16S rRNA methylase gene, conferring resistance to plazomicin, among invasive ST258 and ST16 KPC-producing Klebsiella pneumoniae. Journal of Global Antimicrobial Resistance 24, pp. 183-189. (10.1016/j.jgar.2020.12.006)
- Tansawai, U. et al. 2021. Emergence of mcr-3-mediated IncP and IncFII plasmids in Thailand. Journal of Global Antimicrobial Resistance 24, pp. 446-447. (10.1016/j.jgar.2021.02.006)
- Chalker, V. J. et al. 2021. Tetracycline resistance mediated by tet(M) has variable integrative conjugative element composition in Mycoplasma hominis isolated in the United Kingdom from 2005-2015.. Antimicrobial Agents and Chemotherapy 65, article number: e02513-20. (10.1128/AAC.02513-20)
- Naha, S., Sands, K., Mukherjee, S., Saha, B., Dutta, S., Basu, S. and Bradford, P. A. 2021. OXA-181-like carbapenemases in Klebsiella pneumoniae ST14, ST15, ST23, ST48, and ST231 from septicemic neonates: coexistence with NDM-5, resistome, transmissibility, and genome diversity. mSphere 6(1), article number: e01156-20. (10.1128/mSphere.01156-20)
- Morris, D. J., Jones, L. C., Davies, R. L., Sands, K., Portal, E. and Spiller, O. B. 2020. MYCO WELL D-ONE detection of Ureaplasma spp. and Mycoplasma hominis in sexual health patients in Wales. European Journal of Clinical Microbiology and Infectious Diseases 39, pp. 2427-2440. (10.1007/s10096-020-03993-7)
- Martins, W. M. B. S. et al. 2020. Clinical and molecular description of a high-copy IncQ1 KPC-2 plasmid harbored by the international ST15 Klebsiella pneumoniae clone. mSphere 5, article number: e00756-20. (10.1128/mSphere.00756-20)
- Andrey, D. O. et al. 2020. An emerging clone, KPC-2-producing Klebsiella pneumoniae ST16, associated with high mortality rates in a CC258 endemic setting. Clinical Infectious Diseases 71(7), pp. e141-e150. (10.1093/cid/ciz1095)
- Farzana, R. et al. 2020. Molecular and epidemiological analysis of a Burkholderia cepacia sepsis outbreak from a tertiary care hospital in Bangladesh. PLoS Neglected Tropical Diseases 14(4), article number: e0008200. (10.1371/journal.pntd.0008200)
- Naha, S. et al. 2020. KPC-2-producing Klebsiella pneumoniae ST147 in a neonatal unit: Clonal isolates with differences in colistin susceptibility attributed to AcrAB-TolC pump. International Journal of Antimicrobial Agents 55(3), article number: 105903. (10.1016/j.ijantimicag.2020.105903)
- Yee Lim, S. et al. 2020. Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International Journal of Pharmaceutics 573, article number: 118860. (10.1016/j.ijpharm.2019.118860)
- Mentasti, M., Prime, K., Sands, K., Khan, S. and Wootton, M. 2019. Rapid detection of IMP, NDM, VIM, KPC and OXA-48-like carbapenemases from enterobacteriales and gram-negative non-fermenter bacteria by real-time PCR and melt-curve analysis. European Journal of Clinical Microbiology and Infectious Diseases 38(11), pp. 2029-2036. (10.1007/s10096-019-03637-5)
- Farzana, R. et al. 2019. Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh. Journal of Infection in Developing Countries 13(8), pp. 773-776. (10.3855/jidc.11541)
- Farzana, R. et al. 2019. Outbreak of hypervirulent multi-drug resistant Klebsiella variicola causing high mortality in neonates in Bangladesh. Clinical Infectious Diseases 7, pp. 1225-1227. (10.1093/cid/ciy778)
- Yang, Q. E. et al. 2019. Environmental dissemination of mcr-1 positive Enterobacteriaceae by Chrysomya spp. (common blowfly): An increasing public health risk. Environment International 122, pp. 281-290. (10.1016/j.envint.2018.11.021)
- Sands, K. M. et al. 2017. Respiratory pathogen colonisation of dental plaque, the lower airways and endotracheal tube biofilms during mechanical ventilation. Journal of Critical Care 37, pp. 30-37. (10.1016/j.jcrc.2016.07.019)
- Sands, K. M. et al. 2016. Microbial profiling of dental plaque from mechanically ventilated patients. Journal of Medical Microbiology 65(2), pp. 147-159. (10.1099/jmm.0.000212)
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O., Marsh, L. L. and Wise, M. P. 2014. Mechanisms of augmented growth of Pseudomonas aeruginosa mediated by Candida albicans [Letter]. Critical Care Medicine 42(3), pp. e256. (10.1097/CCM.0000000000000113)
- Sands, K. M., Williams, D. W., Wilson, M. J., Lewis, M. A. O. and Wise, M. P. 2013. The dynamics of polymicrobial biofilms [Letter]. American Journal of Respiratory and Critical Care Medicine 188(10), pp. 1266. (10.1164/rccm.201305-0916LE)
Thesis
Supervision
Past projects