Dr Cleo Bonnet

2024

• Gilbert, S. J., Jones, R., Egan, B. J., Bonnet, C. S., Evans, S. L. and Mason, D. J. 2024. Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D. Frontiers in Endocrinology 15, article number: 1359052. (10.3389/fendo.2024.1359052)

2021

• Gilbert, S. J., Bonnet, C. S. and Blain, E. J. 2021. Mechanical cues: bidirectional reciprocity in the extracellular matrix drives mechano-signalling in articular cartilage. International Journal of Molecular Sciences 22(24), article number: 13595. (10.3390/ijms222413595)

2020

• Bonnet, C. S., Gilbert, S. J., Blain, E. J., Williams, A. S. and Mason, D. J. 2020. AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. JCI Insight 5(13), article number: e134055. (10.1172/jci.insight.134055)

2018

• Gilbert, S. J., Bonnet, C. S., Stadnik, P., Duance, V. C., Mason, D. J. and Blain, E. J. 2018. Inflammatory and degenerative phases resulting from anterior cruciate rupture in a non-invasive murine model of post-traumatic osteoarthritis. Journal of Orthopaedic Research 36(8), pp. 2118-2127. (10.1002/jor.23872)

2017

• Holt, C. A. et al. 2017. Biomechanical and biological indicators of altered knee loading in pre- High Tibial Osteotomy patients. Presented at: ORS 2017 Annual Meeting, San Diego, CA, USA, 19-11 March 2017.

2016

• Holt, C. A. et al. 2016. Biological changes in tibial subchondral bone following high tibial osteotomy. Osteoarthritis and Cartilage 24(S1), pp. S511-S511. (10.1016/j.joca.2016.01.935)

2014

• Bonnet, C. S., Williams, A. S., Gilbert, S. J., Harvey, A. K., Evans, B. A. and Mason, D. J. 2014. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis. Annals of the Rheumatic Diseases 74, pp. 242-251. (10.1136/annrheumdis-2013-203670)
• Gilbert, S. J. et al. 2014. Deletion of P58IPK, the cellular inhibitor of the protein kinases PKR and PERK, causes bone changes and joint degeneration in mice. Frontiers in Endocrinology 5, article number: 174. (10.3389/fendo.2014.00174)
• Bonnet, C., Williams, A. S., Gilbert, S. J., Harvey, A., Evans, B. A. J. and Mason, D. J. 2014. NBQX, a glutamate receptor antagonist, alleviates inflammation, pathology and gait abnormalities in a rat model of inflammatory arthritis. International Journal of Experimental Pathology 95(3), pp. A5-A6. (10.1111/iep.12078)
• Holt, C. A., Whatling, G. M., Bonnet, C., Brakspear, K., Wilson, C., Williams, R. and Mason, D. J. 2014. Correlating biomechanics and biological signals in subjects undergoing high tibial osteotomy. Presented at: Othopaedic Research Society, New Orleans, LA, USA, 15-18th March 2014.

2012

• Bonnet, C., Williams, A. S., Harvey, A., Gilbert, S. J., Moideen, A. N., Nowell, M. A. and Mason, D. J. 2012. Intra-articular AMPA/kainate glutamate receptor antagonists alleviate inflammation, pain and pathology in rat antigen induced arthritis [Abstract]. Osteoporosis International 23, pp. S527-S527.

2009

• Bonnet, C., Aldred, M., Von Ruhland, C. J., Harris, R., Sandford, R. and Cheadle, J. P. 2009. Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis. Human Molecular Genetics 18(12), pp. 2166-2176. (10.1093/hmg/ddp149)
• Bonnet, C. 2009. Investigating the mechanism of renal cystogenesis in tuberous sclerosis and polycystic kidney disease. PhD Thesis, Cardiff University.

2006

• Wilson, C. H. et al. 2006. Tsc1 Haploinsufficiency without Mammalian Target of Rapamycin Activation Is Sufficient for Renal Cyst Formation in Tsc1+/- Mice. Cancer Research 66(16), pp. 7934-8. (10.1158/0008-5472.CAN-06-1740)