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Dr Helen Brown

Dr Helen Brown

Lecturer - Microbiology (T&R)

Email
brownh19@cardiff.ac.uk
Telephone
+44 (0)29 2087 4595
Campuses
W2/12, Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Users
Available for postgraduate supervision

Overview

I am a Lecturer in Microbiology. My research interest is in multispecies biofilm formation, opportunistic bacterial infections, interactions within bacterial communities and host-microbial interactions. My current research focuses on interactions between fibroblasts and opportunistic pathogens within chronic wound infections. Prior to starting my PhD, I worked for six years in the pharmaceutical industry, using mammalian cell-based assays to assess drug biological safety and potency.

Biography

Publications

2022

2021

2020

2015

2014

2013

Teaching

I teach on the following modules:

BI1001 Skills for Science
BI1003 Organisms and the Environment
BI2332 Concepts of Disease
BI3155 Infection biology and Epidemiology 

I am also available to supervise BSc, MSc and MRes students

Bacterial-host interactions:

  • Interactions between fibroblasts (and their secreted components) and their influence on Staphylococcus aureus pathogenicity
  • Understanding how mixed species bacterial communities respond to the host secretome

Bacterial-bacterial interactions:

  • Understanding how the interplay between commensals and opportunistic pathogens can drive pathogenicity and persistence
  • Using the commensal microbiome community to control opportunistic pathogens

Novel therapeutic interventions for chronic wounds:

  • Using microwaves to stimulate dermal wound healing and resolve chronic wound infections
  • Novel antimicrobial/antibiofilm therapeutic strategies utilising the host secretome

Supervision